Why is "Δ-opioid receptor" trending?

Search Interest Perspective

• BPS Publications - British Pharmacological Society | Journals
• Single-molecule characterization of opioid receptor heterodimers reveals soluble µ-δ dimer blocker peptide alleviates morphine tolerance - Nature
• Extracellular processing of proopiomelanocortin generates short beta endorphin that regulates rat keratinocytes via the delta opioid receptor - Nature
• Insights into the interaction between hemorphins and δ-opioid receptor from molecular modeling - Frontiers
• Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity - PNAS
• Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists - Science | AAAS
• Opioid-Induced Pronociceptive Signaling in the Gastrointestinal Tract Is Mediated by Delta-Opioid Receptor Signaling - Journal of Neuroscience
• Delta Opioid Receptor Identified as Promising Therapeutic Target for Inflammatory Pain Relief - New York University
• Delta Opioid Receptor Agonists Show Promise for Faster, Safer Depression Treatments - Inside Precision Medicine
• The Delta-Opioid Receptor; a Target for the Treatment of Pain - Frontiers
• Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists - Science | AAAS
• Molecular control of δ-opioid receptor signalling - Nature
• Delta opioid receptor agonists activate PI3K–mTORC1 signaling in parvalbumin-positive interneurons in mouse infralimbic prefrontal cortex to exert acute antidepressant-like effects - Nature
• Structure-guided design of partial agonists at an opioid receptor - Nature
• Structural basis for bifunctional peptide recognition at human δ-opioid receptor - Nature
• Structure of the δ-opioid receptor bound to naltrindole - Nature
• Cryo-EM structure of small-molecule agonist bound delta opioid receptor-G - Nature
• Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function - Nature
• Functional significance of opioid receptor homomers and heteromers - Nature
• Cell surface targeting of μ-δ opioid receptor heterodimers by RTP4 - PNAS
• Single-molecule methods for characterizing receptor dimers reveal metastable opioid receptor homodimers that induce functional modulation - Nature
• Forebrain delta opioid receptors regulate the response of delta agonist in models of migraine and opioid-induced hyperalgesia - Nature
• HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor Signaling - Journal of Neuroscience
• Kappa opioid receptor control of motivated behavior revisited - Nature
• Agonists of the opioid δ-receptor improve irritable bowel syndrome-like symptoms via the central nervous system - British Pharmacological Society | Journals
• Genetic Dissociation of Opiate Tolerance and Physical Dependence in δ-Opioid Receptor-1 and Preproenkephalin Knock-Out Mice - Journal of Neuroscience
• Structural basis of μ-opioid receptor targeting by a nanobody antagonist - Nature
• Inflammatory Pain Relief That Targets Delta Opioid Receptor May Have Fewer Side Effects - Genetic Engineering and Biotechnology News
• Morphine-induced mechanical hypersensitivity in mice requires δ receptors, β-arrestin2, and c-Src activity - Wiley
• Molecular Medicine Reports - Spandidos Publications
• β -Endorphin via the Delta Opioid Receptor is a Major Factor in the Incubation of Cocaine Craving - Nature
• Agonist-induced phosphorylation bar code and differential post-activation signaling of the delta opioid receptor revealed by phosphosite-specific antibodies - Nature
• The δ -Opioid Receptor Agonist (+)BW373U86 Regulates BDNF mRNA Expression in Rats - Nature
• In vivo mapping of a GPCR interactome using knockin mice - PNAS
• Coexpression of δ- and μ-opioid receptors in nociceptive sensory neurons - PNAS
• Study examines the differences between opioid receptor subtypes - Medical Xpress
• Differences in δ - and μ -Opioid Receptor Blockade Measured by Positron Emission Tomography in Naltrexone-Treated Recently Abstinent Alcohol-Dependent Subjects - Nature
• Morphine and Pain-Related Stimuli Enhance Cell Surface Availability of Somatic δ-Opioid Receptors in Rat Dorsal Root Ganglia - Journal of Neuroscience
• The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist - Nature
• UF researchers identify safer pathway for pain relief - UF Health
• Prolonged Morphine Treatment Targets δ Opioid Receptors to Neuronal Plasma Membranes and Enhances δ-Mediated Antinociception - Journal of Neuroscience
• Disruption of the Na+ ion binding site as a mechanism for positive allosteric modulation of the mu-opioid receptor - PNAS
• Impaired Hippocampus-Dependent and Facilitated Striatum-Dependent Behaviors in Mice Lacking the Delta Opioid Receptor - Nature
• Design, synthesis and biological evaluation of N-phenylalkyl-substituted tramadol derivatives as novel μ opioid receptor ligands - Nature
• Distinct Mu, Delta, and Kappa Opioid Receptor Mechanisms Underlie Low Sociability and Depressive-Like Behaviors During Heroin Abstinence - Nature
• Delta Opioid Receptor May Be a Target for Inflammatory Pain Relief - Dentistry Today
• Antidepressant-like and anxiolytic-like effects following activation of the μ-δ opioid receptor heteromer in the nucleus accumbens - Nature
• Chronic Heroin Self-Administration Desensitizes μ Opioid Receptor-Activated G-Proteins in Specific Regions of Rat Brain - Journal of Neuroscience
• One-step generation of mice carrying a conditional allele together with an HA-tag insertion for the delta opioid receptor - Nature
• μ-Opioid and δ-Opioid Receptors Are Expressed in Brainstem Antinociceptive Circuits: Studies Using Immunocytochemistry and Retrograde Tract-Tracing - Journal of Neuroscience
• Heteromerization Modulates mu Opioid Receptor Functional Properties in vivo - Frontiers
• Augmentation of Morphine-Induced Sensitization but Reduction in Morphine Tolerance and Reward in Delta-Opioid Receptor Knockout Mice - Nature
• Candidate genes for anorexia nervosa in the 1p33–36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa - Nature
• A Safer Opioid Alternative: New Drug Offers Pain Relief Without Dangerous Side Effects - SciTechDaily