Why is "1,3-BPG" trending?

Search Interest Perspective

• Inosine promotes erythrocyte metabolic reprogramming and restores oxygen release for rejuvenation via 2,3-BPG-PNP axis - Nature
• Anoxia-adapted Cyanobacteria In A Marine Blue Hole - astrobiology.com
• 2,3-Diphosphoglycerate: the forgotten metabolic regulator of oxygen affinity - Cambridge University Press & Assessment
• The CILLO-E Hypothesis: Erythrocyte-Driven Acidosis and Early Eryptosis as Drivers of Cancer-Associated Anemia - Frontiers
• Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport–Luebering glycolytic shunt - PNAS
• Targeted LC-MS profiling reveals dysregulated glycolytic flux and TCA cycle stalling in POAG plasma - Nature
• Targeting the red cell enzyme pyruvate kinase with a small allosteric molecule AG-348 may correct underlying pathology of a glycolytic enzymopathy - Haematologica
• Concentration of 2,3 bisphosphoglycerate in cattle affected with acute ruminal acidosis - onlinelibrary.wiley.com
• Interaction of Human 3-Phosphoglycerate Kinase with Its Two Substrates: Is Substrate Antagonism a Kinetic Advantage? - ScienceDirect.com
• The glycolytic and fermentative pathway as they were modeled in this study. - PLOS
• A Reactive Metabolite Makes a New PTM - Genetic Engineering and Biotechnology News
• Erythropoiesis–inosine metabolic axis failure underlying retinal neurodegeneration in glaucoma: novel diagnoses and therapies | Experimental & Molecular Medicine - Nature
• Erythrocyte metabolism - Chatzinikolaou - 2024 - Acta Physiologica - onlinelibrary.wiley.com
• Glyceraldehyde-3-phosphate dehydrogenase homologs as bifunctional gatekeepers of metabolic segregation in Pseudomonas putida - PNAS
• Identification of a novel non-ATP-competitive protein kinase inhibitor of PGK1 from marine nature products - ScienceDirect.com
• Thermal proteome profiling reveals fructose-1,6-bisphosphate as a phosphate donor to activate phosphoglycerate mutase 1 - Nature
• DJ-1 protects proteins from acylation by catalyzing the hydrolysis of highly reactive cyclic 3-phosphoglyceric anhydride - Nature
• Impaired glycolysis-derived serine metabolism as a key driver of podocyte injury with senescence - Nature
• Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate - Nature
• Targeting glycolytic enzymes to combat cancer metastasis: Strategies toward clinical translation - ScienceDirect.com
• Phthalide Derivatives from Angelica Sinensis Decrease Hemoglobin Oxygen Affinity: A New Allosteric-Modulating Mechanism and Potential Use as 2,3-BPG Functional Substitutes - Nature
• Progress of research on glucose transporter proteins in hepatocellular carcinoma - Baishideng Publishing Group
• Pareto Optimality Explanation of the Glycolytic Alternatives in Nature - Nature
• An intronic polymorphism associated with 2,3-bisphosphoglycerate levels in human red cells is linked to expression of RhCE blood groups - PNAS
• Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core - Nature
• Lower glycolysis carries a higher flux than any biochemically possible alternative - Nature
• A GTP-driven central carbon metabolism in the cellulolytic bacterium Ruminiclostridium cellulolyticum - Nature
• Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia - Nature
• Alteration in the number, morphology, function, and metabolism of erythrocytes in high-altitude polycythemia - Frontiers
• Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease - Nature
• Increasing lipid production in Chlamydomonas reinhardtii through genetic introduction for the overexpression of glyceraldehyde-3-phosphate dehydrogenase - Frontiers
• Longevity Humans Have Youthful Erythrocyte Function and Metabolic Signatures - Yu - 2025 - Aging Cell - onlinelibrary.wiley.com
• Targeting phosphoglycerate kinases by tatridin A, a natural sesquiterpenoid endowed with anti-cancer activity, using a proteomic platform - Frontiers
• A novel gluconeogenic route enables efficient use of erythritol in zoonotic Brucella - Frontiers
• The Discovery of Novel PGK1 Activators as Apoptotic Inhibiting and Neuroprotective Agents - Frontiers
• Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite - PNAS
• Into Thin Air: Genetic Factors Drive Metabolic Adaptations Linked to Acclimatization - University of Colorado Anschutz
• Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect - Frontiers
• Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway - Nature
• Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation - Nature
• The oxygen dissociation curve of blood in COVID-19–An update - Frontiers
• Metabolite profiling of Arabidopsis mutants of lower glycolysis - Nature
• Repurposing Lamivudine: A novel therapeutic strategy for ischemic stroke targeting the glycolytic enzyme Pgk1 - ScienceDirect.com
• JAK2 unmutated erythrocytosis: current diagnostic approach and therapeutic views - Nature
• Metabolic disorder of nutrients—an emerging field in the pathogenesis of preeclampsia - Frontiers
• Erythrocytosis in congenital heart defects: hints for diagnosis and therapy from a clinical case - Frontiers
• Erythrocytosis associated with a novel missense mutation in the BPGM gene - Haematologica
• JAK2 Unmutated Erythrocytosis: 2026 Update on Diagnosis and Management - onlinelibrary.wiley.com
• channel. The permeability of human and mouse red cell membranes for oxygen - American Physiological Society Journal
• Dimeric assembly of F1-like ATPase for the gliding motility of Mycoplasma - Science | AAAS
• Reduction of Glycolysis Intermediate Concentrations in the Cerebrospinal Fluid of Alzheimer’s Disease Patients - Frontiers
• Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate - Nature
• Effects of 2,3‐DPG knockout on SCD phenotype in Townes SCD model mice - onlinelibrary.wiley.com
• Dynamics of camel and human hemoglobin revealed by molecular simulations - Nature
• Preview: Chargers host Lake Erie to kick off G-MAC play - hillsdalechargers.com
• New Insight into the Role of the Calvin Cycle: Reutilization of CO - Nature
• Physiology and central carbon metabolism of the gut bacterium Prevotella copri - onlinelibrary.wiley.com
• Victor Wembanyama | Forward-Center | San Antonio Spurs - NBA
• Scientists Discover a New Type of Protein Modification that May Play a Role in Cancer and Diabetes - technologynetworks.com
• Metabolomic alterations in human cancer cells by vitamin C-induced oxidative stress - Nature
• Antibiotic Regimens | Group A Strep - cdc.gov
• Victor Wembanyama - ESPN
• Victor Wembanyama 2025-26 Stats per Game - NBA - ESPN
• Nosema ceranae , Fipronil and their combination compromise honey bee reproduction via changes in male physiology - Nature
• Chet Holmgren - ESPN
• Trial data support 1-dose antibiotic treatment for early syphilis - CIDRAP
• Clinical utility gene card for: familial erythrocytosis - Nature
• Evan Mobley - ESPN
• Happy Valley leads BPG Award nominations - Televisual
• Myles Turner - ESPN
• Nikola Jokic - ESPN
• Shai Gilgeous-Alexander - ESPN
• Draymond Green - ESPN
• Post-translational modification of PGK1 found as a key signal in tumor growth - Mirage News
• Nominations announced for 2025 BPG Awards - Televisual
• Anthony Davis - ESPN
• Podcast nominees among those confirmed for 2026 BPG Awards - PodcastingToday
• BBC Radio 2 and Radio 4 feature in BPG nominations - radiotoday.uk