Why is "11-Deoxycorticosterone" trending?
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- Date: 2026-03-13 13:44:10
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Wikipedia Overview
11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. It is an active (Na+-retaining) mineralocorticoid. As its names indicate, 11-deoxycorticosterone can be understood as the 21-hydroxy-variant of progesterone or as the 11-deoxy-variant of corticosterone.
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Trending Topic Today
Search Interest Perspective
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A Case of Deoxycorticosterone-Producing Adrenocortical Carcinoma: A Review of Etiologies of Hypertension With Hypokalemia - ACP Journals
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Phase 2a Study of Baxdrostat in Primary Aldosteronism - NEJM
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Urinary steroid metabolome shows adrenal, gonadal, and neuroactive steroid dysregulation in adolescents with depression - medRxiv
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Once-Daily Treatment for Cushing Syndrome May Safely Restore Cortisol Rhythms - Physician's Weekly
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From Severe Virilization to Precocious Puberty in a 46,XX Patient: Therapeutic Challenges in a Case of 11β-Hydroxylase Deficiency - Cureus
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Results from a phase 1, randomized, double-blind, multiple ascending dose study characterizing the pharmacokinetics and demonstrating the safety and selectivity of the aldosterone synthase inhibitor baxdrostat in healthy volunteers - Nature
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Multiplexed steroid profiling of gluco- and mineralocorticoids pathways using a liquid chromatography tandem mass spectrometry method - ScienceDirect.com
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Etomidate-induced hypokalemia in electronic cigarette users: two case reports and literature review - Frontiers
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Mineralocorticoids show utility as type 2 diabetes, prediabetes biomarkers - Healio
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Use of Steroidogenic Precursors for Evaluation of Adrenocortical Carcinoma in Adrenal Masses: A Case Series - Consultant360
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Profiling of adrenal corticosteroids in blood and local tissues of mice during chronic stress - Nature
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The Complex Spectrum of 11β-Hydroxylase Deficiency: A Case of Precocious Puberty, Hypertension, and Testicular Adrenal Rest Tumors (TARTs) - Cureus
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Challenges in treatment of patients with non-classic congenital adrenal hyperplasia - Frontiers
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The adrenal steroid profile in adolescent depression: a valuable bio-readout? - Nature
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Baseline and Corticotropin-Stimulated Blood Steroid Profiles in Women of Reproductive Age in India: A Cross-Sectional Study and Global Literature Review - Cureus
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Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein Assemblies - Frontiers
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11-Deoxycortisol controls hydromineral balance in the most basal osmoregulating vertebrate, sea lamprey ( Petromyzon marinus - Nature
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Glucocorticoids and mineralocorticoids in hair: facilitating accurate diagnosis of adrenal-related endocrine disorders - Frontiers
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Steroid Profiling as an Additional Tool to Confirm One-Sided Hormone Overproduction in Primary Aldosteronism: A Case Report - Frontiers
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Corticosteroid Biosynthesis Revisited: No Direct Hydroxylation of Pregnenolone by Steroid 21-Hydroxylase - Frontiers
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Steroids: Aging and Stroke Effects - Endocrine Society
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Hormonal profile changes induced by pesticide mixture exposure in female rats revealed by hair analysis - ScienceDirect.com
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Egg-mediated maternal effects in a cooperatively breeding cichlid fish - Nature
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Integrative analysis of the gut microbiota and metabolome in rats treated with rice straw biochar by 16S rRNA gene sequencing and LC/MS-based metabolomics - Nature
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Genetic, Cellular, and Molecular Heterogeneity in Adrenals With Aldosterone-Producing Adenoma - American Heart Association Journals
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Using skin mucus for the identification of ovulation biomarkers in North American Atlantic salmon ( Salmo salar - ScienceDirect.com
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The 3D in vitro Adrenoid cell model recapitulates the complexity of the adrenal gland - Nature
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Phase 2a Baxdrostat Data Show Promise for Primary Aldosteronism - HCPLive
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Cellular contribution to left and right atrial dysfunction in chronic arterial hypertension in pigs - Wiley Online Library
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The mineralocorticoid receptor knockout in medaka is further validated by glucocorticoid receptor compensation - Nature
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Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes - Nature
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Novel Antihypertensive Reduced Blood Pressure in Primary Aldosteronism - MedPage Today
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Snout dated: Slow-evolving elephant shark offers new insights into human physiology - EurekAlert!
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A more accurate diagnosis of Cushing’s syndrome - News-Medical
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A Novel Mutation in the CYP11B1 Gene Causes Steroid 11β‐Hydroxylase Deficient Congenital Adrenal Hyperplasia with Reversible Cardiomyopathy - Wiley Online Library
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Aldosterone synthase deficiency due to homozygous CYP11B2 pathogenic variant with coexisting celiac disease: A case study and literature review - Termedia
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L/N-type calcium channel blocker cilnidipine ameliorates proteinuria and inhibits the renal renin–angiotensin–aldosterone system in deoxycorticosterone acetate-salt hypertensive rats - Nature
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Secondary Biosynthetic Defects in Women with Late-Onset Congenital Adrenal Hyperplasia - NEJM
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