Why is "12-lipoxygenase" trending?

Search Interest Perspective

• Status epilepticus-induced 12/15-lipoxygenase drives neuroinflammation and contributes to neuronal injuries and behavioral comorbidities | Acta Pharmacologica Sinica - Nature
• Oroxylin A attenuates sepsis-associated coagulopathy by targeting the ALOX12-lipid peroxidation - ScienceDirect.com
• Experimental obesity-diabetes drug flips ‘off switch’ on inflammation - Stock Titan
• Cadrenal Therapeutics Highlights Research Supporting 12-LOX Inhibition in Reducing Inflammation in Obesity and Type 2 Diabetes - Sahm
• Correction to: Loss of 12-Lipoxygenase Improves the Post-Transfusion Function of Stored Platelets - American Heart Association Journals
• Cadrenal Therapeutics Highlights Research Supporting 12-LOX Inhibition in Reducing Inflammation in Obesity and Type 2 Diabetes - ChartMill
• Cadrenal Therapeutics highlights research on 12-LOX inhibition - TipRanks
• CVKD: Acquires 12-LOX Inhibitor for the Treatment of Heparin-Induced Thrombocytopenia (HIT) - Yahoo Finance
• Deficiency in platelet 12-lipoxygenase exacerbates inflammation and disease severity during SARS-CoV-2 infection - PNAS
• Cadrenal Therapeutics (CVKD) spotlights CAD-1005 12-LOX data in obesity, diabetes and HIT - Stock Titan
• Pla2g7 regulates bone homeostasis via Alox12/12-HETE/Gpr31 signaling axis - Nature
• Metabolomics reveals pro-inflammatory effects of 12R-HETE and ALOX12B in maternal allergic asthma - Nature
• Loss of 12-Lipoxygenase Improves the Post-Transfusion Function of Stored Platelets - American Heart Association Journals
• Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development - PNAS
• Modulation of Neuroinflammation in Poststroke Rehabilitation: The Role of 12/15-Lipoxygenase Inhibition and Baicalein - American Heart Association Journals
• Inhibition of PGK1 ameliorates acute kidney injury through inactivating the PKM2/ALOX12/ferroptosis pathway in a study with male mice - Nature
• Fatty acid desaturation and lipoxygenase pathways support trained immunity - Nature
• Activation of ALOX12 by a multi-organelle-orienting photosensitizer drives ACSL4-independent cell ferroptosis - Nature
• Central Interaction of 2-Methoxyestradiol and Lipoxygenase in AngII-Hypertension - American Heart Association Journals
• Chronic social defeat stress increases the amounts of 12-lipoxygenase lipid metabolites in the nucleus accumbens of stress-resilient mice - Nature
• Ovariectomy Via 12/15-lipoxygenase Augments Angiotensin II-Induced Hypertension and Its Pathogenesis in Female Mice - American Heart Association Journals
• Hematopoietic 12/15-lipoxygenase activity negatively contributes to fungal-associated allergic asthma - American Physiological Society Journal
• A small molecule targeting ALOX12-ACC1 ameliorates nonalcoholic steatohepatitis in mice and macaques - Science | AAAS
• Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition - American Heart Association Journals
• Inhibition of 12/15-lipoxygenase by baicalein induces microglia PPARβ/δ: a potential therapeutic role for CNS autoimmune disease | Cell Death & Disease - Nature
• Increased 15-lipoxygenase-1 expression in chondrocytes contributes to the pathogenesis of osteoarthritis - Nature
• 12/15-lipoxygenase activity promotes efficient inflammation resolution in a murine model of Lyme arthritis - Frontiers
• 15-Lipoxygenase promotes resolution of inflammation in lymphedema by controlling T - Nature
• 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma - Nature
• Pharmacologic blockade of 12/15-lipoxygenase ameliorates memory deficits, Aβ and tau neuropathology in the triple-transgenic mice - Nature
• Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway - Nature
• Macrophage 12(S)-HETE Enhances Angiotensin II–Induced Contraction by a BLT2 (Leukotriene B - American Heart Association Journals
• Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2 - ScienceDirect.com
• Regulation and Functions of 15-Lipoxygenases in Human Macrophages - Frontiers
• Controlling the Clot: ANXA7 Regulates Collagen Activation of Platelet Through 12-LOX - American Heart Association Journals
• Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase - Nature
• -induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway - Nature
• Dr. Honn receives prestigious Chancellor's Award from LSU - Today@Wayne
• Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA - PNAS
• Lipid Receptor GPR31 (G-Protein–Coupled Receptor 31) Regulates Platelet Reactivity and Thrombosis Without Affecting Hemostasis - American Heart Association Journals
• WFDC12-overexpressing contributes to the development of atopic dermatitis via accelerating ALOX12/15 metabolism and PAF accumulation - Nature
• First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis - American Heart Association Journals
• Novel 12-LOX Inhibitor Fast Tracked for Heparin-Induced Thrombocytopenia - Medical Professionals Reference
• Inhibition of ALOX12–12-HETE Alleviates Lung Ischemia–Reperfusion Injury by Reducing Endothelial Ferroptosis-Mediated Neutrophil Extracellular Trap Formation - Science Partner Journals
• Association of ALOX15 gene polymorphisms with obesity-related phenotypes in Chinese nuclear families with male offspring - Nature
• The emerging role of oxylipins in thrombosis and diabetes - Frontiers
• Controlling the Clot: ANXA7 Regulates Collagen Activation of Platelet Through 12-LOX - American Heart Association Journals
• Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice - Nature
• Lipoxygenases and their involvement in programmed cell death - Nature
• -Induced Mitochondrial Lipid Peroxidation through Increasing ALOX12 Expression - Science Partner Journals
• Efferocyte-Derived MCTRs Metabolically Prime Macrophages for Continual Efferocytosis via Rac1-Mediated Activation of Glycolysis - Wiley
• Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase - Nature
• Plant sterol fortified soy milk shows inflammation benefits: Singapore study - NutraIngredients.com
• Expression, subcellular localization and putative function of platelet-type 12-lipoxygenase in human prostate cancer cell lines of different metastatic potential - Wiley Online Library