Why is "2,3-Methylenedioxyamphetamine" trending?
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Trend Analysis
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- Date: 2026-03-09 03:22:13
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
2,3-Methylenedioxyamphetamine, also known as 2,3-MDA or as ortho-MDA, is an amphetamine derivative which is mentioned in PiHKAL as a fairly potent and long-lasting stimulant drug, but with little or none of the entactogenic effects associated with its better-known structural isomer MDA.
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Search Interest Perspective
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Subjective and neurocognitive profiling of clinical doses of 3,4-methylenedioxymethamphetamine (MDMA) in healthy volunteers: implications for therapeutic use - Nature
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MDA 2026: Biogen, Sarepta, Edgewise Address Muscle Disorders - BioSpace
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History, pharmacology and therapeutic mechanisms of 3,4-methylenedioxymethamphetamine (MDMA) - British Pharmacological Society | Journals
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Acute effects of MDMA, MDA, lysine-MDMA, and lysine-MDA in a randomized, double-blind, placebo-controlled, crossover trial in healthy participants | Neuropsychopharmacology - Nature
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Structure and bystander killing effect of anti-HER2-SHR169265 ADCs. - PLOS
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Characterization of 3,4-Methylenedioxymethamphetamine (MDMA) Enantiomers In Vitro and in the MPTP-Lesioned Primate: R-MDMA Reduces Severity of Dyskinesia, Whereas S-MDMA Extends Duration of ON-Time - Journal of Neuroscience
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The Efficacy of MDMA (3,4-Methylenedioxymethamphetamine) for Post-traumatic Stress Disorder in Humans: A Systematic Review and Meta-Analysis - Cureus
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Hepatic injury and hepatic failure adverse events in 3,4-methylenedioxymethamphetamine users reported to the FDA Adverse Event Reporting System - Frontiers
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Norway vs. Moldova - Final Score - September 09, 2025 - FOX Sports
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The predictive value of microfilariae-based stop-MDA thresholds after triple drug therapy with IDA in treatment-naive Indian settings - medRxiv
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New chlorinated amphetamine-type-stimulants disinfection-by-products formed during drinking water treatment - ScienceDirect.com
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Effect of mass drug administration on malaria incidence in southeast Senegal during 2020–22: a two-arm, open-label, cluster-randomised controlled trial - The Lancet
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3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy: what the pharmacist needs to know - Wiley Online Library
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3,4-Methylenedioxymethamphetamine Increases Affiliative Behaviors in Squirrel Monkeys in a Serotonin 2A Receptor-Dependent Manner - Nature
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MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial - Nature
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Acute effects of R -MDMA, S -MDMA, and racemic MDMA in a randomized double-blind cross-over trial in healthy participants - Nature
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The influence of the host microbiome on 3,4-methylenedioxymethamphetamine (MDMA)-induced hyperthermia and vice versa - Nature
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Distinct acute effects of LSD, MDMA, and d-amphetamine in healthy subjects | Neuropsychopharmacology - Nature
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Ethanol, 3,4-Methylenedioxymethamphetamine (Ecstasy) and Their Combination: Long-Term Behavioral, Neurochemical and Neuropharmacological Effects in the Rat - Nature
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Acute Effects of 3,4-Methylenedioxymethamphetamine (MDMA) on Behavioral Measures of Impulsivity: Alone and in Combination with Alcohol - Nature
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US Navy and MDA Successfully Intercept Multiple Targets In Integrated Air and Missile Defense Test - DVIDS
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Malaria resurgence after significant reduction by mass drug administration on Ngodhe Island, Kenya - Nature
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L-Tyrosine Contributes to (+)-3,4-Methylenedioxymethamphetamine-Induced Serotonin Depletions - Journal of Neuroscience
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Pharmacokinetic Profile of Single and Repeated Oral Doses of MDMA in Squirrel Monkeys: Relationship to Lasting Effects on Brain Serotonin Neurons - Nature
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Small Changes in Ambient Temperature Cause Large Changes in 3,4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonin Neurotoxicity and Core Body Temperature in the Rat - Journal of Neuroscience
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Parthenolide prevents resistance of MDA-MB231 cells to doxorubicin and mitoxantrone: the role of Nrf2 - Nature
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Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties - Nature
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MDA Tests Two SM-3 Variants in Three Days - SpaceNews
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C3 AI Secures 3 MDA Orders Under $500M Production OTA; Ed Abbo Quoted - GovCon Wire
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Hydrogen phosphate selectively induces MDA MB 231 triple negative breast cancer cell death in vitro - Nature
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L-Tyrosine Contributes to (+)-3,4-Methylenedioxymethamphetamine-Induced Serotonin Depletions - Journal of Neuroscience
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MDA Extends Deadline for Golden Dome Proposals - Air & Space Forces Magazine
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Synthesis of potent MDA-MB 231 breast cancer drug molecules from single step - Nature
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MDA: Test of DDG, Standard Missile-3 IIA a Good Start, But More Work Needed on Homeland Defense Mission - USNI News
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Diagnostic target product profiles for monitoring, evaluation and surveillance of schistosomiasis control programmes - World Health Organization (WHO)
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Three-megadalton complex of methanogenic electron-bifurcating and CO2-fixing enzymes - Science | AAAS
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Altered Serotonin Innervation Patterns in the Forebrain of Monkeys Treated with (±)3,4-Methylenedioxymethamphetamine Seven Years Previously: Factors Influencing Abnormal Recovery - Journal of Neuroscience
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Development of tetraculture spheroids as a versatile 3D model for personalized breast cancer research - Nature
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Cytotoxicity of eupatorin in MCF-7 and MDA-MB-231 human breast cancer cells via cell cycle arrest, anti-angiogenesis and induction of apoptosis - Nature
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Acute Psychological Effects of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) are Attenuated by the Serotonin Uptake Inhibitor Citalopram - Nature
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MDA: Reimagining space missions with mixed reality - Microsoft Source
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Metabolic adaptability in metastatic breast cancer by AKR1B10-dependent balancing of glycolysis and fatty acid oxidation - Nature
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Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice - Science | AAAS
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hnRNPK S379 phosphorylation participates in migration regulation of triple negative MDA-MB-231 cells - Nature
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MDA extends satellite operations capability through contract - MDA Space
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Moldova 0-2 Lithuania (Mar 26, 2026) Final Score - ESPN
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mda -9/Syntenin promotes metastasis in human melanoma cells by activating c-Src - PNAS
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Overexpression of HER-2 in MDA-MB-435/LCC6 Tumours is Associated with Higher Metabolic Activity and Lower Energy Stress - Nature
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The UPR inducer DPP23 inhibits the metastatic potential of MDA-MB-231 human breast cancer cells by targeting the Akt–IKK–NF-κB–MMP-9 axis - Nature
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MEDIA ADVISORY - MDA SPACE TO HOLD ITS THIRD QUARTER 2025 EARNINGS CONFERENCE CALL ON NOVEMBER 14, 2025 - Yahoo! Finance Canada
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Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids - Nature
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RTX Lands $1B MDA Contract for Standard Missile-3 Block IB All-Up Rounds - GovCon Wire
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In situ characterizing membrane lipid phenotype of breast cancer cells using mass spectrometry profiling - Nature
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Assessment of plasma malondialdehyde levels among free-diver fishermen in southeast Maluku district: exploring influencing factors on oxidative stress | Sulfiana | International Maritime Health - Via Medica Journals
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Moldova 0-2 Italy (Nov 13, 2025) Final Score - ESPN
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The pharmacology and toxicology of “ecstasy” (MDMA) and related drugs - CMAJ
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Estonia vs. Moldova - Final Score - October 14, 2025 - FOX Sports
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N -Substituted Piperazines Abused by Humans Mimic the Molecular Mechanism of 3,4-Methylenedioxymethamphetamine (MDMA, or ‘Ecstasy’) - Nature
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MDA | Award Winners 2025 - Midwest Design
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Northrop Grumman Vs Raytheon: A Closer Look At The MDA's Glide Phase Interceptor Program - Simple Flying
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MDA is Now MDA Space - SpaceQ
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