Why is "2-Deoxy-D-glucose" trending?

Search Interest Perspective

• The effect of 2-Deoxy-D-glucose on glycolytic metabolism in acute myeloblastic leukemic ML-1 cells - Nature
• 2-Deoxy-D-Glucose and its Derivatives for the COVID-19 Treatment: An Update - Frontiers
• A catabolic block does not sufficiently explain how 2-deoxy- d -glucose inhibits cell growth - PNAS
• Glucose-functionalized gold nanoparticles for effective photothermal therapy in lung cancer - Nature
• 2-Deoxy-2-fluoro-d-glucose metabolism in Arabidopsis thaliana - Frontiers
• 2 deoxy-D-glucose augments the mitochondrial respiratory chain in heart - Nature
• 2-Deoxyglucose and Beta-Hydroxybutyrate: Metabolic Agents for Seizure Control - Frontiers
• 2-Deoxy-D-Glucose inhibits aggressive triple-negative breast cancer cells by targeting glycolysis and the cancer stem cell phenotype - Nature
• Differential Effects of 2-Deoxyglucose and Glucose Deprivation on 4-Hydroxynonenal Dependent Mitochondrial Dysfunction in Primary Neurons - Frontiers
• Metabolic profiling of attached and detached metformin and 2-deoxy-D-glucose treated breast cancer cells reveals adaptive changes in metabolome of detached cells - Nature
• 2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA - Nature
• Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death | British Journal of Cancer - Nature
• Low-dose 2-deoxyglucose and metformin synergically inhibit proliferation of human polycystic kidney cells by modulating glucose metabolism - Nature
• Non-thermal plasma with 2-deoxy-D-glucose synergistically induces cell death by targeting glycolysis in blood cancer cells - Nature
• Matrix metalloproteinase-2 as a novel regulator of glucose utilization by adipocytes - Nature
• Induction of glioblastoma cell ferroptosis using combined treatment with chloramphenicol and 2-deoxy- - Nature
• A composite patch loaded with 2-Deoxy Glucose facilitates cardiac recovery after myocardial infarction via attenuating local inflammatory response - Nature
• [13C6,D8]2-deoxyglucose phosphorylation by hexokinase shows selectivity for the β-anomer | Scientific Reports - Nature
• -glucose regulates dedifferentiation through β-catenin pathway in rabbit articular chondrocytes - Nature
• Chemical exchange saturation transfer MRI shows low cerebral 2-deoxy-D-glucose uptake in a model of Alzheimer’s Disease - Nature
• Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis - Nature
• BPS Publications - British Pharmacological Society | Journals
• Controlling Herpes Simplex Virus-Induced Immunoinflammatory Lesions Using Metabolic Therapy: a Comparison of 2-Deoxy- d -Glucose with Metformin - ASM Journals
• 2-Deoxyglucose and Newcastle Disease Virus Synergize to Kill Breast Cancer Cells by Inhibition of Glycolysis Pathway Through Glyceraldehyde3-Phosphate Downregulation - Frontiers
• Nebulized 2-deoxylated glucose analogues inhibit respiratory viral infection in advanced in vitro airway models - Nature
• The combination of hydroxychloroquine and 2-deoxyglucose enhances apoptosis in breast cancer cells by blocking protective autophagy and sustaining endoplasmic reticulum stress - Nature
• WP1122 is a 2-deoxy-D-glucose prodrug in pre-clinical development for glioblastoma - TLTC Blogs |
• Dynamic 2-deoxy-2[18F] fluoro-D-glucose PET/MRI in human renal allotransplant patients undergoing acute kidney injury - Nature
• Application of the 2-deoxyglucose scaffold as a new chiral probe for elucidation of the absolute configuration of secondary alcohols - Nature
• -glucose in combination: a potential treatment for breast and prostate cancer - Nature
• Combination of glycolysis inhibition with chemotherapy results in an antitumor immune response - PNAS
• Early interim 2-(1)fluoro-2-deoxy-D-glucose positron emission tomography is prognostically superior to peripheral blood lymphocyte/monocyte ratio at diagnosis in classical Hodgkin’s lymphoma - Haematologica
• Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy - ScienceDirect.com
• Post-click labeling enables highly accurate single cell analyses of glucose uptake ex vivo and in vivo - Nature
• Oncology Reports - Spandidos Publications
• Dual metabolic reprogramming by ONC201/TIC10 and 2-Deoxyglucose induces energy depletion and synergistic anti-cancer activity in glioblastoma - Nature
• Case report: Evaluation of cutaneous squamous cell carcinoma metastasized to lymph nodes using - Frontiers
• F]-sodium fluoride in genetically modified Apolipoprotein E knock-out and wild type mice - Nature
• -glucose epimerization in Pseudomonas putida KT2440 - Nature
• In-vivo topical mucosal delivery of a fluorescent deoxy-glucose delineates neoplasia from normal in a preclinical model of oral epithelial neoplasia | Scientific Reports - Nature
• Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism - Nature
• Embryonic Stem Cell Proliferation Stimulated By Altered Anabolic Metabolism From Glucose Transporter 2-Transported Glucosamine | Scientific Reports - Nature
• In Vitro and In Vivo Characterization of 2-Deoxy-2-18F-Fluoro-d-Mannose as a Tumor-Imaging Agent for PET - Journal of Nuclear Medicine
• Characterization of Macrophage Polarization States Using Combined Measurement of 2-Deoxyglucose and Glutamine Accumulation: - American Heart Association Journals
• cancer stem cells, EMT-MET, and glucose metabolism in breast cancer - Nature
• Bacterial processing of glucose modulates C. elegans lifespan and healthspan - Nature
• Primary and Recurrent Early Stage Laryngeal Cancer: Preliminary Results of 2-[Fluorine 18]fluoro-2-deoxy- d -glucose PET Imaging1 - RSNA Journals
• Targeting the ROS/PI3K/AKT/HIF-1α/HK2 axis of breast cancer cells: Combined administration of Polydatin and 2-Deoxy-d-glucose - Wiley Online Library
• Near-simultaneous intravital microscopy of glucose uptake and mitochondrial membrane potential, key endpoints that reflect major metabolic axes in cancer - Nature
• SLC50A1 inhibits the doxorubicin sensitivity in hepatocellular carcinoma cells through regulating the tumor glycolysis - Nature
• Does 2-FDG PET Accurately Reflect Quantitative In Vivo Glucose Utilization? - Journal of Nuclear Medicine
• Dr Reddy's shares important information on DRDO's 2-DG Covid drug. Details here - Mint
• Revisiting Glycogen in Cancer: A Conspicuous and Targetable Enabler of Malignant Transformation - Frontiers
• Low glucose availability potentiates the effects of metformin on model T cell activation and exhaustion markers in vitro - Frontiers
• Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells - Wiley
• Molecular imaging of tumors and metastases using chemical exchange saturation transfer (CEST) MRI - Nature
• 2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP–dependent metabolic regulation of chromatin structure - Nature
• G6Pase location in the endoplasmic reticulum: Implications on compartmental analysis of FDG uptake in cancer cells - Nature
• Controlling glycolysis to generate characteristic volatile organic compounds of lung cancer cells - Nature
• Autocrine FGF1 signaling promotes glucose uptake in adipocytes - PNAS
• Glucose metabolism regulates expression of hair-inductive genes of dermal papilla spheres via histone acetylation - Nature
• Changes in Glycolytic Pathway in SARS-COV 2 Infection and Their Importance in Understanding the Severity of COVID-19 - Frontiers
• Chronic inhibition of brain glycolysis initiates epileptogenesis - Wiley Online Library
• Additive effect of radiosensitization by 2-deoxy-D-glucose delays DNA repair kinetics and suppresses cell proliferation in oral squamous cell carcinoma - Wiley Online Library
• Preoperative prediction of the pathological stage of advanced gastric cancer by - Nature
• Propranolol sensitizes prostate cancer cells to glucose metabolism inhibition and prevents cancer progression - Nature
• Glucosamine and N-acetyl glucosamine as new CEST MRI agents for molecular imaging of tumors - Nature
• A Mathematical Model for Enzyme Clustering in Glucose Metabolism - Nature
• An approach to develop personalized radiopharmaceuticals by modifying - Via Medica Journals
• F-18 Fluoro-2-Deoxyglucose Positron Emission Tomography (PET)/Computed Tomography (CT) Imaging in Melanoma: Normal Variants, Pitfalls, and Artifacts - Frontiers
• "All That Glitters Is Not Gold" - A Case of an Occult Foreign Body in the Lung with Elevated 2-[18F]-Fluoro-2-deoxy-D-glucose (FDG) Uptake Mimicking Bronchogenic Carcinoma - Cureus
• DCGI approves anti-COVID drug developed by DRDO for emergency use - The Hindu
• Use of 18F‐2‐deoxy‐2‐fluoro‐D‐glucose positron emission tomography/computed tomography for staging thyroid carcinoma in a cat - Wiley Online Library
• Noninvasive diagnosis of solitary pulmonary lesions in cancer patients based on 2-fluoro-2-deoxy-D-glucose avidity on positron emission tomography/computed tomography - Wiley
• What is 2-Deoxy-D-Glucose drug, the new anti-Covid drug? How does it work? - Healthcare Radius
• Indian DCGI grants emergency approval to DRDO’s anti-Covid-19 2-DG - Pharmaceutical Technology
• Evaluation of 18F-2-deoxy-2-fluoro-glucose positron emission tomography for gastric cancer screening in asymptomatic individuals undergoing endoscopy | British Journal of Cancer - Nature
• Utilizing Synergistic Potential of Mitochondria-Targeting Drugs for Leukemia Therapy - Frontiers
• Metabolites of 18F-FDG and 3-O-11C-Methylglucose in Pig Liver - Journal of Nuclear Medicine
• Quantitative techniques in 18FDG PET scanning in oncology - British Journal of Cancer - Nature
• Access to DRDO drug 2-DG will improve in weeks: Dr. Reddy’s - The Hindu
• 4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8 - Nature
• Cerebral Glucose Metabolism Measured by Positron Emission Tomography in Term Newborn Infants with Hypoxic Ischemic Encephalopathy - Nature
• Coronavirus treatment: Everything we know about DRDO's COVID medicine, 2-deoxy-D-glucose - The Times of India
• Synthesis of Thienamycin methyl ester from 2-deoxy-d-ribose via Kinugasa reaction | The Journal of Antibiotics - Nature
• Non-Toxic Method for Treating Cancer Developed - Genetic Engineering and Biotechnology News
• Dr. Reddy’s announces commercial launch of 2-DG - The Hindu
• High Uric Acid Induces Insulin Resistance in Cardiomyocytes In Vitro and In Vivo - PLOS
• Bajaj Healthcare gets a go-ahead for 2-Deoxy-D-Glucose to treat Covid-19 - Indian Pharma Post
• Fact Check: False information about immediate procurement of anti-Covid drug 2-DG goes viral, Dr Reddy's clarifies - India Today
• Preoperative lymph node staging of early-stage cervical carcinoma by [ - Wiley
• The Hypothermia of Hypoglycemia — Studies with 2-Deoxy-D-Glucose in Normal Human Subjects and Mice - NEJM
• All you need to know about DRDO's 2-Deoxy-D-Glucose drug - Medical Dialogues
• Rs 990 Per Sachet For Defence Research Body's Covid Drug '2-DG': Report - NDTV
• 2-DG UPDATE: Dr Reddy's Lab commercially launches 2-deoxy-D-glucose TODAY; Priced it at Rs 990/sachet - Zee Business
• Drug Overcomes Chemotherapy Resistance in Ovarian Cancer, Study Shows - Docwire News
• Explained: How does 2-DG, DRDO’s new oral drug for Covid-19, work? - The Indian Express
• Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver - PNAS
• Granules India gets licence from DRDO to manufacture and market COVID-19 drug 2-DG - The Economic Times
• -mannose positron emission tomography imaging in atherosclerosis - Nature