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The 2010 United States Senate election in Arizona took place on November 2, 2010, along with other elections to the United States Senate in other states as well as elections to the United States House of Representatives and various state and local elections. The primaries were held on August 24, 2010. Incumbent Republican U.S. Senator John McCain, who had lost the 2008 presidential election to then-United States Senator from Illinois Barack Obama, ran for reelection to a fifth term and won, defeating Democratic challenger Rodney Glassman. As of 2026, this was the last time the counties of Coconino and Pima voted for the Republican candidate. Glassman later switched to the Republican Party and ran as a Republican for Arizona Attorney General in 2026.
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