Why is "AKR1B1" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-17 20:07:45
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
Aldo-keto reductase family 1, member B1 (AKR1B1) is an gene in humans that encodes the enzyme aldose reductase. It is a reduced nicotinamide-adenine dinucleotide phosphate (NADPH)-dependent enzyme catalyzing the reduction of various aldehydes and ketones to the corresponding alcohol. The involvement of AKR1B1 in oxidative stress diseases, cell signal transduction, and cell proliferation process endows AKR1B1 with potential as a therapeutic target.
Read more on Wikipedia →Related Topics
Trending Topic Today
Search Interest Perspective
-
Clinical impact of the methylation status of SMAD4 and AKR1B1 genes in a liquid biopsy sample as a prognostic marker for breast cancer - Nature
-
AKR1B1 Expression in the Colorectal Tumor Microenvironment Contributes Towards Its Prognostic Significance - Wiley Online Library
-
AKR1B1 is potential marker of therapy resistance in liver cancer - BioWorld MedTech
-
Naringenin restores osteogenic differentiation in TNF-α-Treated bone marrow mesenchymal stem cells by targeting AKR1B1 - Nature
-
In silico characterization of the interaction of AKR1B1 with the deacetylase activation domain (DAD) - Frontiers
-
Targeting AKR1B1 inhibits glutathione de novo synthesis to overcome acquired resistance to EGFR-targeted therapy in lung cancer - Science | AAAS
-
Already reported aldo-keto reductase inhibitors [14, 15]. - PLOS
-
Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10 - PNAS
-
AKR1B1-dependent fructose metabolism enhances malignancy of cancer cells | Cell Death & Differentiation - Nature
-
The prostaglandin F synthase activity of the human aldose reductase AKR1B1 brings new lenses to look at pathologic conditions - Frontiers
-
ZNF521/EBF1 axis regulates AKR1B1 to promote the proliferation, migration, and invasion of gastric cancer cells - Wiley Online Library
-
Targeting AKR1B1 inhibits glutathione de novo synthesis to overcome acquired resistance to EGFR-targeted therapy in lung cancer - Science | AAAS
-
Expression of the Aldo-Ketoreductases AKR1B1 and AKR1B10 in Human Cancers - Frontiers
-
Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer - Nature
-
Regulation of Aldo–Keto Reductases in Human Diseases - Frontiers
-
Fructose: the sweet(er) side of the Warburg effect - Nature
-
Enzymes of the AKR1B and AKR1C Subfamilies and Uterine Diseases - Frontiers
-
Aldo–Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers - Frontiers
-
Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation - Nature
-
Aldose Reductase B1 in Pig Sperm Is Related to Their Function and Fertilizing Ability - Frontiers
-
Evidence of fructose metabolism in colorectal cancer - Nature
-
Machine learning based intratumor heterogeneity signature for predicting prognosis and immunotherapy benefit in stomach adenocarcinoma - Nature
-
Olfactory cleft biopsy analysis of Alzheimer’s disease pathobiology across disease stages - Nature
-
Identifying Common Genetic Risk Factors of Diabetic Neuropathies - Frontiers
-
Targeted Detection of Phospholipid Aldehydes in Living Cells by Oxime Ligation - Wiley Online Library
-
The polyol pathway and nuclear ketohexokinase A signaling drive hyperglycemia-induced metastasis of gastric cancer - Nature
-
Simiao Decoction Alleviates Gouty Arthritis by Modulating Proinflammatory Cytokines and the Gut Ecosystem - Frontiers
-
Aldo-Keto Reductases 1B in Endocrinology and Metabolism - Frontiers
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.