Why is "ARF6" trending?

Search Interest Perspective

• Autism spectrum disorder-associated Sema5A p.Arg676Cys drives Arf6/FE65 signaling and aberrant cell morphogenesis - Nature
• Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice - American Heart Association Journals
• Arf6 GTPase deficiency leads to porcine oocyte quality decline during aging - Zhang - 2024 - Wiley
• Requirement for Arf6 in breast cancer invasive activities - PNAS
• Roles of Arf6 in cancer cell invasion, metastasis and proliferation - ScienceDirect.com
• Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy - Nature
• Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice - American Heart Association Journals
• EFA6 controls Arf1 and Arf6 activation through a negative feedback loop - PNAS
• O -Fucosyltransferase SPINDLY attenuates auxin-induced fruit growth by inhibiting ARF6/8-coactivator mediator complex interaction in Arabidopsis - Nature
• Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion - Nature
• Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system - Nature
• CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling - Nature
• NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle - Nature
• Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen - Nature
• Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism - Nature
• Activation of the GTPase ARF6 regulates invasion of human vascular smooth muscle cells by stimulating MMP14 activity - Nature
• The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing - Nature
• EGFR/ARF6 regulation of Hh signalling stimulates oncogenic Ras tumour overgrowth - Nature
• An ARF6–Exportin-5 axis delivers pre-miRNA cargo to tumour microvesicles - Nature
• Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling - Nature
• Trans -regulation of oligodendrocyte myelination by neurons through small GTPase Arf6-regulated secretion of fibroblast growth factor-2 - Nature
• Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2 - Nature
• Rab14 specifies the apical membrane through Arf6-mediated regulation of lipid domains and Cdc42 - Nature
• DDR1 promotes hepatocellular carcinoma metastasis through recruiting PSD4 to ARF6 - Nature
• Activation of the Small G Protein Arf6 by Dynamin2 through Guanine Nucleotide Exchange Factors in Endocytosis - Nature
• Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis - Nature
• Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe - Nature
• Arf6 exchange factor EFA6 and endophilin directly interact at the plasma membrane to control clathrin-mediated endocytosis - PNAS
• Interleukin receptor activates a MYD88–ARNO–ARF6 cascade to disrupt vascular stability - Nature
• A role for the Auxin Response Factors ARF6 and ARF8 homologs in petal spur elongation and nectary maturation in Aquilegia - Wiley
• Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer - Nature
• ZEB1 induces EPB41L5 in the cancer mesenchymal program that drives ARF6-based invasion, metastasis and drug resistance - Nature
• Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP - Nature
• Structural elucidation of how ARF small GTPases induce membrane tubulation for vesicle fission - PNAS
• V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway - Nature
• Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity - Nature
• The C-terminal domain of EFA6A interacts directly with F-actin and assembles F-actin bundles - Nature
• Structure of Arf6–GDP suggests a basis for guanine nucleotide exchange factors specificity - Nature
• Structural basis for the ARF GAP activity and specificity of the C9orf72 complex - Nature
• Extracellular microvesicles and invadopodia mediate non-overlapping modes of tumor cell invasion - Nature
• BRAG2a Mediates mGluR-Dependent AMPA Receptor Internalization at Excitatory Postsynapses through the Interaction with PSD-95 and Endophilin 3 - Journal of Neuroscience
• Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis - PNAS
• Snf1/AMP-activated protein kinase activates Arf3p to promote invasive yeast growth via a non-canonical GEF domain - Nature
• ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly - Nature
• Oliver Sacks’ Rare Eye Disease Gives Rise to New Strategy for Treating Difficult Cancers - University of Utah Health
• Virus Control of Trafficking from Sorting Endosomes - ASM Journals
• Broad distribution of ARF6 in somatic and germ cells of the sea urchin ovary - Wiley Online Library
• Researchers Identify Protein That Plays Key Role in Diabetic Blindness - University of Utah Health
• Crystal structure of Sec10, a subunit of the exocyst complex - Nature
• Even Nicotine-Free Vapes Can Damage Lung Tissue: One Protein Plays a Key Role - ScienceAlert
• Arl13b regulates endocytic recycling traffic - PNAS