Why is "ASK1" trending?

Search Interest Perspective

• NOD1 deficiency promotes inflammation via autophagic degradation of ASK1 - Nature
• Neratinib Targets Vascular Inflammation in Atherosclerosis Models - European Medical Journal
• ASK1 signaling regulates phase-specific glial interactions during neuroinflammation - PNAS
• TurboID-based proteomic profiling reveals proxitome of ASK1 and CUL1 of the SCF ubiquitin ligase in plants - Wiley
• -induced impairment of evoked dopamine release in the mouse hippocampus - Frontiers
• ASK1 inhibits browning of white adipose tissue in obesity - Nature
• DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis - PNAS
• Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer - Nature
• Apoptosis signal-regulating kinase 1 promotes inflammation in senescence and aging - Nature
• in the balance of cell-cycle arrest, cell death and tumorigenesis of stressed keratinocytes - Nature
• ASK1 signalling regulates brown and beige adipocyte function - Nature
• ASK1-ER stress pathway-mediated fibrotic-EV release contributes to the interaction of alveolar epithelial cells and lung fibroblasts to promote mechanical ventilation-induced pulmonary fibrosis - Nature
• ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes - Nature
• ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice - Nature
• Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut - Nature
• Role of GALNT4 in protecting against cardiac hypertrophy through ASK1 signaling pathway - Nature
• Glutathione peroxidase-1 regulates ASK1-dependent apoptosis via interaction with TRAF2 in RIPK3-negative cancer cells - Nature
• ASK1 promotes the contact hypersensitivity response through IL-17 production - Nature
• ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction - Nature
• Glutathione S-transferase Mu 2 inhibits hepatic steatosis via ASK1 suppression - Nature
• The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis - Nature
• Novel therapeutic strategies targeting ASK1 in NASH - Nature
• ASK1 signaling regulates phase-specific glial interactions during neuroinflammation - PNAS
• Redox Regulation of Cardiac ASK1 (Apoptosis Signal-Regulating Kinase 1) Controls p38-MAPK (Mitogen-Activated Protein Kinase) and Orchestrates Cardiac Remodeling to Hypertension - American Heart Association Journals
• Inhibition of apoptosis signal-regulating kinase 1 enhances endochondral bone formation by increasing chondrocyte survival - Nature
• Zinc finger protein ZPR9 functions as an activator of AMPK-related serine/threonine kinase MPK38/MELK involved in ASK1/TGF-β/p53 signaling pathways - Nature
• Apoptosis signal-regulating kinase 1 (ASK1) is linked to neural stem cell differentiation after ischemic brain injury - Nature
• trans -Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway - Nature
• -induced apoptosis via suppression of ASK1-P38-NF-κB pathway in SH-SY5Y cells - Nature
• Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia - Nature
• PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis - Nature
• Binding activity of H-Ras is necessary for in vivo inhibition of ASK1 activity - Nature
• ASK1 deficiency attenuates neural cell death in GLAST-deficient mice, a model of normal tension glaucoma - Nature
• Short AIP1 (ASK1-Interacting Protein-1) Isoform Localizes to the Mitochondria and Promotes Vascular Dysfunction - American Heart Association Journals
• ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity - Nature
• Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK–ERK independent mechanism - PNAS
• ASK1 resistant neuroblastoma is deficient in activation of p38 kinase - Nature
• Apoptosis Signal-regulating Kinase 1 promotes Ochratoxin A-induced renal cytotoxicity - Nature
• Genetic variation in the TNF/TRAF2/ASK1/p38 kinase signaling pathway as markers for postoperative pulmonary complications in lung cancer patients - Nature
• Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation - Nature
• ASK-1 activation exacerbates kidney dysfunction via increment of glomerular permeability and accelerates cellular aging in diabetic kidney disease model mice - Nature
• Erratum: ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice - Nature
• Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer - PNAS
• Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation - Nature
• Multiomic insight into the involvement of cell aging related genes in the pathogenesis of endometriosis - Nature
• Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins - PNAS
• Hsp90–Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis - Nature
• Thioredoxin-interacting protein deficiency protects against severe acute pancreatitis by suppressing apoptosis signal-regulating kinase 1 - Nature
• HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell - Nature
• MTA2 silencing attenuates the metastatic potential of cervical cancer cells by inhibiting AP1-mediated MMP12 expression via the ASK1/MEK3/p38/YB1 axis - Nature
• Hepatocellular SETDB1 Regulates Hepatic Ischemia-Reperfusion Injury through Targeting Lysine Methylation of ASK1 Signal - Science Partner Journals
• Apoptosis signal-regulating kinase 1 mediates striatal degeneration via the regulation of C1q - Nature
• Iron mitigates DMT1-mediated manganese cytotoxicity via the ASK1-JNK signaling axis: Implications of iron supplementation for manganese toxicity - Nature
• ASK family kinases mediate cellular stress and redox signaling to circadian clock - PNAS
• ASK the enzyme: new potential targets for cancer - Asia Research News |
• SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis - Nature
• Human glutathione S -transferase P1-1 interacts with TRAF2 and regulates TRAF2–ASK1 signals - Nature
• Seal Rock Therapeutics Announces Upcoming Presentations at AASLD's The Liver Meeting® 2020 - BioSpace
• to S phase transition protein 1 induces apoptosis signal-regulating kinase 1 activation by dissociating 14-3-3 from ASK1 - Nature
• ASK1 MAP3K5 ) as a potential therapeutic target in malignant fibrous histiocytomas with 12q14–q15 and 6q23 amplifications - Wiley Online Library
• Eucalyptol antagonized the apoptosis and immune dysfunction of grass carp hepatocytes induced by tetrabromobisphenol A by regulating ROS/ASK1/JNK pathway - Wiley Online Library
• Rational Design, Synthesis and Evaluation of Novel C6‐Bicycloalkaneimidazole Containing Imidazo[1,2‐b]pyridazines for ASK1 Inhibition - Wiley Online Library
• TRAF1 is a critical regulator of cerebral ischaemia–reperfusion injury and neuronal death - Nature
• The thioredoxin system in retroviral infection and apoptosis - Nature
• TNF- α response of vascular endothelial and vascular smooth muscle cells involve differential utilization of ASK1 kinase and p73 - Nature
• The miR-17 ∼ 92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis - Frontiers
• Cell cycle-dependent Cdc25C phosphatase determines cell survival by regulating apoptosis signal-regulating kinase 1 - Nature
• Stress pathway outputs are encoded by pH-dependent clustering of kinase components - Nature
• Thioredoxin-interacting protein in diabetic retinal neurodegeneration: A novel potential therapeutic target for diabetic retinopathy - Frontiers
• BBR induces apoptosis in HepG2 cell through an Akt-ASK1-ROS-p38MAPKs-linked cascade - Wiley Online Library
• Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death - Nature
• Kerala’s first exclusive Aadhaar service centre opened in Kochi - The New Indian Express