Why is "ATP7A" trending?

Search Interest Perspective

• Retropseudogene insertion generated through retrotransposition in the ATP7A gene results in premature stop codons and a case of Menkes disease - Frontiers
• First Treatment for Menkes Disease: FDA Approves Copper Histidinate - MPR - Medical Professionals Reference
• Metallothioneins regulate ATP7A trafficking and control cell viability during copper deficiency and excess - Nature
• ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis - PNAS
• Alpha-synuclein null mutation exacerbates the phenotype of a model of Menkes disease in female mice - Frontiers
• Copper Transporter ATP7A (Copper-Transporting P-Type ATPase/Menkes ATPase) Limits Vascular Inflammation and Aortic Aneurysm Development: - American Heart Association Journals
• Cuproptosis-related molecular patterns and gene (ATP7A) in hepatocellular carcinoma and their relationships with tumor immune microenvironment and clinical features - Wiley Online Library
• Organ-specific regulation of ATP7A abundance is coordinated with systemic copper homeostasis | Scientific Reports - Nature
• Copper transporter potential new treatment target for cardiovascular disease - Augusta University News
• Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease - PNAS
• Identification of a Novel ATP7A Variant in a Chinese Boy With Developmental Delay and Epilepsy - Wiley Online Library
• The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2 - Nature
• Role of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis - Frontiers
• In vivo correction of a Menkes disease model using antisense oligonucleotides - PNAS
• CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual - Nature
• The interplay between copper metabolism and microbes: in perspective of host copper-dependent ATPases ATP7A/B - Frontiers
• ATP7A-related copper transport diseases—emerging concepts and future trends - Nature
• Metal-Dependent Regulation of ATP7A and ATP7B in Fibroblast Cultures - Frontiers
• Unfavorable switching of skewed X chromosome inactivation leads to Menkes disease in a female infant - Nature
• Quantitative Ubiquitinomics Revealed Abnormal Ubiquitinated ATP7A Involved in Down-Regulation of ACTH in Silent Corticotroph Adenomas - Frontiers
• Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer - Nature
• Leishmania major -induced alteration of host cellular and systemic copper homeostasis drives the fate of infection - Nature
• Oral Elesclomol Treatment Alleviates Copper Deficiency in Animal Models - Frontiers
• Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes - Nature
• CMT May Be Linked to Low Copper Levels, Iowa Study Suggests - charcot-marie-toothnews.com
• Functional copper transport explains neurologic sparing in Occipital Horn syndrome - Nature
• Occipital horn syndrome and classical Menkes Syndrome caused by deep intronic mutations, leading to the activation of ATP7A pseudo-exon - Nature
• Structure of the Wilson disease copper transporter ATP7B - Science | AAAS
• Identification of a Novel Deep Intronic Variant by Whole Genome Sequencing Combined With RNA Sequencing in a Chinese Patient With Menkes Disease - Frontiers
• Genome-wide RNAi ionomics screen reveals new genes and regulation of human trace element metabolism - Nature
• Regulating copper homeostasis of tumor cells to promote cuproptosis for enhancing breast cancer immunotherapy - Nature
• Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway - Nature
• Menkes disease complicated by concurrent ACY1 deficiency: A case report - Frontiers
• A matricellular protein fibulin-4 is essential for the activation of lysyl oxidase - Science | AAAS
• Menkes Disease, Causes, Symptoms, Treatment, Latest News - Vajiram & Ravi
• Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity - PNAS
• New evidence of how exercise can counter diabetes damage - Augusta University News
• Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set - Frontiers
• Copper excess in diabetes hinders our ability to make healthy blood vessels - Augusta University News
• Neonatal Diagnosis and Treatment of Menkes Disease - NEJM
• Cuproptosis: Mechanisms, biological significance, and advances in disease treatment—A systematic review - Wiley Online Library
• Copper homeostasis and cuproptosis in atherosclerosis: metabolism, mechanisms and potential therapeutic strategies - Nature
• Gene Replacement Treats Copper Deficiency Disorder in Mice - National Institute of Child Health and Human Development (.gov)
• Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content - Journal of Neuroscience
• Lyonization Effects of the t(X;16) Translocation on the Phenotypic Expression in a Rare Female With Menkes Disease - Nature
• Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein - Nature
• Clinical features and molecular landscape of cuproptosis signature-related molecular subtype in gastric cancer - Wiley Online Library
• -methylthiosemicarbazone) on the macular mouse, an animal model of Menkes disease - Nature
• A new Caenorhabditis elegans model to study copper toxicity in Wilson disease - Catalano - 2024 - Traffic - Wiley Online Library
• Menkes Syndrome Market Projected to Grow at 8.5% CAGR by 2033 - Market.us Media
• Gene therapy hope for Menkes Disease - Understanding Animal Research
• Local 4-year-old living with Menkes Disease - WCTV