Why is "Acetyl-CoA carboxylase" trending?

Search Interest Perspective

• Acetyl-CoA carboxylase maintains energetic balance for functional oogenesis - Nature
• YhcB mediates growth-phase control of fatty acid biosynthesis through regulation of acetyl-CoA carboxylase - ASM Journals
• Acetyl-CoA carboxylase 1 knockdown promotes esophageal squamous cell carcinoma metastasis via the CXCL8–NET axis - Nature
• Acetyl-CoA Carboxylases and Diseases - Frontiers
• Filament structures unveil the dynamic organization of human acetyl-CoA carboxylase - Science | AAAS
• The subcellular localization of acetyl-CoA carboxylase 2 - PNAS
• Advanced glycation end products exacerbate lipopolysaccharide-induced acute lung injury with diabetes by promoting ferroptosis via AMP-activated protein kinase/acetyl-CoA carboxylase signaling - Nature
• Feedback regulation of plastidic acetyl-CoA carboxylase by 18:1-acyl carrier protein in Brassica napus - PNAS
• Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism - Science | AAAS
• Targeting acetyl-CoA carboxylase 1 for cancer therapy - Frontiers
• Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation - PNAS
• Structural basis for regulation of human acetyl-CoA carboxylase - Nature
• Recombinant yeast screen for new inhibitors of human acetyl-CoA carboxylase 2 identifies potential drugs to treat obesity - PNAS
• Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities - Nature
• Acetyl-CoA-carboxylase 1 (ACC1) plays a critical role in glucagon secretion - Nature
• Docking of acetyl-CoA carboxylase to the plastid envelope membrane attenuates fatty acid production in plants - Nature
• A novel multidomain acyl-CoA carboxylase in Saccharopolyspora erythraea provides malonyl-CoA for de novo fatty acid biosynthesis | Scientific Reports - Nature
• The dynamic organization of fungal acetyl-CoA carboxylase - Nature
• Acetyl-CoA-Carboxylase 1-mediated de novo fatty acid synthesis sustains Lgr5 - Nature
• Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer - Nature
• Inhibition of acetyl-CoA carboxylase by spirotetramat causes growth arrest and lipid depletion in nematodes - Nature
• Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake - PNAS
• Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models - Nature
• Biochemical and structural characterization of quizalofop-resistant wheat acetyl-CoA carboxylase - Nature
• Screening Phosphorylation Site Mutations in Yeast Acetyl-CoA Carboxylase Using Malonyl-CoA Sensor to Improve Malonyl-CoA-Derived Product - Frontiers
• Chloroflexus aurantiacus acetyl-CoA carboxylase evolves fused biotin carboxylase and biotin carboxyl carrier protein to complete carboxylation activity - ASM Journals
• Acetyl-CoA carboxylase 1 controls a lipid droplet–peroxisome axis and is a vulnerability of endocrine-resistant ER - Science | AAAS
• Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice - PNAS
• Depletion of Acetyl-CoA Carboxylase 1 Facilitates Epithelial-Mesenchymal Transition in Prostate Cancer Cells by Activating the MAPK/ERK Pathway - Wiley Online Library
• Silencing acetyl-CoA carboxylase A and sterol regulatory element-binding protein 1 genes through RNAi reduce serum and egg cholesterol in chicken - Nature
• RNAi knockdown of acetyl-CoA carboxylase gene eliminates jinggangmycin-enhanced reproduction and population growth in the brown planthopper, Nilaparvata lugens - Nature
• WZ66, a novel acetyl-CoA carboxylase inhibitor, alleviates nonalcoholic steatohepatitis (NASH) in mice - Nature
• Regulation of human Th9 cell differentiation by lipid modulators targeting PPAR-γ and acetyl-CoA-carboxylase 1 - Frontiers
• A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation - Nature
• Genes encoding plastid acetyl-CoA carboxylase and 3-phosphoglycerate kinase of the Triticum Aegilops complex and the evolutionary history of polyploid wheat - PNAS
• The influence of AccD5 on AccD6 carboxyltransferase essentiality in pathogenic and non-pathogenic Mycobacterium - Nature
• SomaLogic proteomics reveals new biomarkers and provides mechanistic, clinical insights into Acetyl coA Carboxylase (ACC) inhibition in Non-alcoholic Steatohepatitis (NASH) - Nature
• Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition - Science | AAAS
• Single-site mutations in the carboxyltransferase domain of plastid acetyl-CoA carboxylase confer resistance to grass-specific herbicides - PNAS
• Genomic characterisation and dissection of the onset of resistance to acetyl CoA carboxylase-inhibiting herbicides in a large collection of Digitaria insularis from Brazil - Frontiers
• Complex nested promoters control tissue-specific expression of acetyl-CoA carboxylase genes in wheat - PNAS
• Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets - PNAS
• Acetyl‐coenzyme A carboxylases: Versatile targets for drug discovery - Wiley Online Library
• Fatty acid synthesis is inhibited by inefficient utilization of unusual fatty acids for glycerolipid assembly - PNAS
• The enzymes of biotin dependent CO2 metabolism: What structures reveal about their reaction mechanisms - Wiley Online Library
• Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase - Nature
• A Chemogenomic Screen Reveals Novel Snf1p/AMPK Independent Regulators of Acetyl-CoA Carboxylase - PLOS
• BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains - Nature
• Sequence and structural similarities of ACCase protein of Phalaris minor and wheat: An insight to explain herbicide selectivity - Frontiers
• Mechanism of metamifop inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in Echinochloa crus-galli - Nature
• Andrimid producers encode an acetyl-CoA carboxyltransferase subunit resistant to the action of the antibiotic - PNAS
• Arabidopsis trigalactosyldiacylglycerol1 mutants reveal a critical role for phosphtidylcholine remodeling in lipid homeostasis - Wiley Online Library
• Herbicidal Activity and Molecular Docking Study of Novel ACCase Inhibitors - Frontiers