Why is "Aconitase" trending?

Search Interest Perspective

• Critical role of mitochondrial aconitase in skeletal muscle maturation - Nature
• From bacteria to mitochondria: Aconitase yields surprises - PNAS
• Aconitase Couples Metabolic Regulation to Mitochondrial DNA Maintenance - Science | AAAS
• Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response - Nature
• Studying Acetylation of Aconitase Isozymes by Genetic Code Expansion - Frontiers
• The molecular evolution of the aconitase superfamily - Phys.org
• Biochemical characterization on muscle tissue of a novel biallelic ACO2 mutation in an infant with progressive encephalopathy - Wiley Online Library
• ACO2 mutations: A novel phenotype associating severe optic atrophy and spastic paraplegia - Neurology® Journals
• Bacillus subtilis aconitase is an RNA-binding protein - PNAS
• Crystal structures of aconitase X enzymes from bacteria and archaea provide insights into the molecular evolution of the aconitase superfamily - Nature
• Itaconate regulates macrophage function through stressful iron-sulfur cluster disrupting and iron metabolism rebalancing - Wiley
• Biochemical elucidation of citrate accumulation in Synechocystis sp. PCC 6803 via kinetic analysis of aconitase - Nature
• Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase - Nature
• Functional characterization of aconitase X as a cis -3-hydroxy-L-proline dehydratase - Nature
• Yeast aconitase mitochondrial import is modulated by interactions of its C and N terminal domains and Ssa1/2 (Hsp70) - Nature
• Aconitase 2 inhibits the proliferation of MCF-7 cells promoting mitochondrial oxidative metabolism and ROS/FoxO1-mediated autophagic response | British Journal of Cancer - Nature
• ACO2 deficiency increases vulnerability to Parkinson’s disease via dysregulating mitochondrial function and histone acetylation-mediated transcription of autophagy genes | Communications Biology - Nature
• E. coli aconitase B structure reveals a HEAT-like domain with implications for protein–protein recognition - Nature
• Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism - Nature
• ACO2 clinicobiological dataset with extensive phenotype ontology annotation - Nature
• Sustainable citric acid production from CO2 in an engineered cyanobacterium - Frontiers
• A [4Fe-4S] cluster resides at the active center of phosphomevalonate dehydratase, a key enzyme in the archaeal modified mevalonate pathway - Frontiers
• Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes - Nature
• Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: Evidence that Yfh1p affects Fe-S cluster synthesis - PNAS
• Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy - Nature
• A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteins - PNAS
• Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts - Nature
• Impact of singular versus combinatorial environmental stress on RONS generation in Drosophila melanogaster larvae - Frontiers
• Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis - Nature
• Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblasts - Nature
• If the RNA Fits, Use It - Science | AAAS
• More ancestral enzyme - Science Codex
• Sodium fluorocitrate having protective effect on palmitate-induced beta cell death improves hyperglycemia in diabetic db/db mice - Nature
• Study Reveals Salmonella’s Hideout Strategy - Global Biodefense
• Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice - PNAS
• Thermodynamic and Kinetic Analyses of Iron Response Element (IRE)-mRNA Binding to Iron Regulatory Protein, IRP1 - Nature
• Oxidative Stress Markers Induced by Hyperosmolarity in Primary Human Corneal Epithelial Cells - PLOS
• Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles - Nature
• “Lethal Synthesis” of Fluorocitrate by Citrate Synthase Explained through QM/MM Modeling - Wiley Online Library
• Study sheds new light on role iron biology plays in disease - University of Alberta
• Inhibition of Krebs Cycle Enzymes by Hydrogen Peroxide: A Key Role of α-Ketoglutarate Dehydrogenase in Limiting NADH Production under Oxidative Stress - Journal of Neuroscience
• aconitase - doccheck.com