Why is "Adenosine" trending?

Search Interest Perspective

• Adenosine surges: A step forward in understanding antidepressant actions of ketamine - Nature
• Adenosine in the Brain: Recent Progress on Detection, Function, and Translation - Journal of Neuroscience
• Long-Term Safety and Efficacy of Gene Therapy for Adenosine Deaminase Deficiency - NEJM
• Adenosine-to-Inosine (A-to-I) RNA Editing by ADAR1 to Control RNA Sensing in Cardiovascular Disease - American Heart Association Journals
• Adenosine receptors on the immuno-oncology expressway: TIME, perspectives, and translation - Frontiers
• Structure-based discovery of positive allosteric modulators of the A1 adenosine receptor - PNAS
• 17 cell pathogenicity through epigenetic and metabolic reprogramming - Science | AAAS
• Squalene-adenosine nanoparticles enhance cardioprotection in myocardial infarction: Efficacy and mechanistic insights - ScienceDirect.com
• Adenosine signalling drives antidepressant actions of ketamine and ECT - Nature
• Differential Effects of Intravenous Versus Intracoronary Adenosine on Non‐Culprit Lesion Assessment Following Acute Coronary Syndrome - American Heart Association Journals
• Remote control of AMPK via extracellular adenosine controls tissue growth - Nature
• The AHCY–adenosine complex rewires mRNA methylation to enhance fatty acid biosynthesis and tumorigenesis - Nature
• Systematic metabolite screening identifies functional regulators of the adenosine A2A receptor - Nature
• -adenosine methylation enhances nuclear mRNA export through METTL3 and NUP93 - Nature
• Selective antagonism of adenosine A2A receptor reduces hypobaric hypoxia-induced neuroinflammation by inhibiting cGAS-STING pathway - Nature
• receptor in astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits - Nature
• ABEL-FRET bridges the timescale gap in single-molecule measurements of the structural dynamics in the A - Nature
• receptor ligands using reinforcement learning and structure-based drug design - Nature
• Inhibition of ENT1 relieves intracellular adenosine-mediated T cell suppression in cancer - Nature
• CXCL10-induced regulatory T cells and adenosine signaling promote immunosuppression and progression of epithelial ovarian cancer - Nature
• Adenosine transmission from hypothalamic tanycytes to AGRP/NPY neurons regulates energy homeostasis - Nature
• Inefficient Maximal Hyperemic Response Following Intravenous Adenosine in Polycythemia: A First-in-the-World Report - JACC Journals
• Adenosine—A drug with myriad utility in the diagnosis and treatment of arrhythmias - Wiley Online Library
• Adenosine-mediated immune responses in inflammatory bowel disease - Frontiers
• Enabling adenosine signaling to promote aged fracture healing - npj Regenerative Medicine - Nature
• Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency - NEJM
• Adenosine signalling to astrocytes coordinates brain metabolism and function - Nature
• receptor agonist elicits analgesia without cardiorespiratory depression - Nature
• Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization - Nature
• Adenosine triggers early astrocyte reactivity that provokes microglial responses and drives the pathogenesis of sepsis-associated encephalopathy in mice - Nature
• Structural insights into the agonist selectivity of the adenosine A - Nature
• receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula - Nature
• Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia - Nature
• Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development - Science | AAAS
• Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice - Nature
• A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment - Frontiers
• Regulation of sleep homeostasis mediator adenosine by basal forebrain glutamatergic neurons - Science | AAAS
• Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity - PNAS
• Extracellular cAMP-Adenosine Pathway Signaling: A Potential Therapeutic Target in Chronic Inflammatory Airway Diseases - Frontiers
• CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy - Nature
• The adenosine pathway in immuno-oncology - Nature
• Anti-obesity effects of the dual-active adenosine A2A/A3 receptor-ligand LJ-4378 | International Journal of Obesity - Nature
• Programmed RNA editing with an evolved bacterial adenosine deaminase - Nature
• Convergence of adenosine and GABA signaling for synapse stabilization during development - Science | AAAS
• Unlocking the adenosine receptor mechanism of the tumour immune microenvironment - Frontiers
• Hypoxia-adenosine axis as therapeutic targets for acute respiratory distress syndrome - Frontiers
• 40 Hz light flickering promotes sleep through cortical adenosine signaling - Nature
• CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression - Nature
• receptor in complex with clinical candidate Etrumadenant reveals unprecedented antagonist interaction - Nature
• Adenosine A2B Receptor: From Cell Biology to Human Diseases - Frontiers
• Inflammatory Bowel Diseases: It's Time for the Adenosine System - Frontiers
• Adenosine A2A receptors control synaptic remodeling in the adult brain - Scientific Reports - Nature
• Neuronal adenosine A2A receptors signal ergogenic effects of caffeine - Scientific Reports - Nature
• Adenosine-Induced Atrioventricular Block in Patients With Unexplained Syncope : - American Heart Association Journals
• Structure of the adenosine-bound human adenosine A1 receptor–Gi complex - Nature
• Editorial: Community series in adenosine pathways in cancer immunity and immunotherapy, volume II - Frontiers
• Gene Therapy for Immunodeficiency Due to Adenosine Deaminase Deficiency - NEJM
• The Role of Adenosine Receptors in Psychostimulant Addiction - Frontiers
• Arousal Effect of Caffeine Depends on Adenosine A2A Receptors in the Shell of the Nucleus Accumbens - Journal of Neuroscience
• Adenosine A2A receptor mediates hypnotic effects of ethanol in mice - Scientific Reports - Nature
• Locomotion activates PKA through dopamine and adenosine in striatal neurons - Nature
• -methyladenosine by enzyme-assisted adenosine deamination - Nature
• Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome - Nature
• Cryo-EM structure of the human adenosine A2B receptor–Gs signaling complex - Science | AAAS
• Adenosine-A2A Receptor Pathway in Cancer Immunotherapy - Frontiers
• Balancing G protein selectivity and efficacy in the adenosine A - Nature
• Adenosine Actions on Oligodendroglia and Myelination in Autism Spectrum Disorder - Frontiers
• Adenosine and Ticagrelor Plasma Levels in Patients With and Without Ticagrelor-Related Dyspnea - American Heart Association Journals
• Adenosine restrains ILC2-driven allergic airway inflammation via A2A receptor - Nature
• Adenosine Concentration in Patients With Neurally Mediated Syncope - Frontiers
• Adenosine triphosphate induces amorphous aggregation of amyloid β by increasing Aβ dynamics - Nature
• Adenosine receptors: therapeutic aspects for inflammatory and immune diseases - Nature
• receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function - Nature
• Adenosine Kinase couples sensing of cellular potassium depletion to purine metabolism - Nature
• Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis - Nature
• Citrulline activates adenosine receptors: New insight into metabolic pathways interaction - ScienceDirect.com
• Adenosine-related small molecules show utility of recall antigen assay to screen compounds for off-target effects on memory T cells - Nature
• receptor on trigeminal nerves orchestrates CGRP release to regulate the progression of oral squamous cell carcinoma - Nature
• Adenosine Receptors Influence Hypertension in Dahl Salt-Sensitive Rats: - American Heart Association Journals
• An adenosine nucleoside inhibitor of dengue virus - PNAS
• Targeting the Adenosine-Mediated Metabolic Immune Checkpoint with Engineered Probiotic for Enhanced Chemo-Immunotherapy - Wiley
• Impairment of adenosine signaling disrupts early embryo development: unveiling the underlying mechanisms - Frontiers
• Structure of an Agonist-Bound Human A2A Adenosine Receptor - Science | AAAS
• Adenosine Receptor and Its Downstream Targets, Mod(mdg4) and Hsp70, Work as a Signaling Pathway Modulating Cytotoxic Damage in Drosophila - Frontiers
• Adenosine diphosphate stimulates VEGF-independent choroidal endothelial cell proliferation: A potential escape from anti-VEGF therapy - PNAS
• Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes - PNAS
• -methyladenosine-dependent and independent impacts on mRNA regulation in Arabidopsis - Wiley
• Mutant Adenosine Deaminase 2 in a Polyarteritis Nodosa Vasculopathy - NEJM
• Inactivation of adenosine receptor 2A suppresses endothelial-to-mesenchymal transition and inhibits subretinal fibrosis in mice - Science | AAAS
• Illuminating the impact of CD38-induced adenosine formation in B-cell lymphoma - Nature
• Reexamination of magnetic isotope and field effects on adenosine triphosphate production by creatine kinase - PNAS
• Cryo-EM structures of adenosine receptor A - Nature
• In vivo RNA editing of point mutations via RNA-guided adenosine deaminases - Nature
• Gating and the Need for Sleep: Dissociable Effects of Adenosine A1 and A2A Receptors - Frontiers
• Adenosine deaminase-related growth factors stimulate cell proliferation in Drosophila by depleting extracellular adenosine - PNAS
• Conversion of extracellular ATP into adenosine: a master switch in renal health and disease - Nature
• Adenosine-Sensitive Upper Septal Fascicular Ventricular Tachycardia Associated With Takotsubo Syndrome - JACC Journals
• Adenosine-Functionalized Biodegradable PLA-b-PEG Nanoparticles Ameliorate Osteoarthritis in Rats - Nature
• Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression - Nature
• Dopamine Release in Nucleus Accumbens Is under Tonic Inhibition by Adenosine A - Journal of Neuroscience