Why is "Aldolase" trending?

Search Interest Perspective

• K11- and K29-ubiquitination-mediated nuclear translocation of glycolytic enzyme aldolase A promotes pancreatic cancer progression by NF-κB activation | Cell Death & Differentiation - Nature
• A Rare Case of Myasthenia Gravis With Underlying Aldolase A Deficiency: Diagnostic and Therapeutic Challenges - Cureus
• Formaldehyde aldolases: Key enzymes in C-C bond formation and C1 assimilation - sciencedirect.com
• Engineered enzymes turn industrial pollutant Into pharmaceutical building block - R&D World
• Deoxyradiofluorination Affords Intracellular Trapping and the Tracing of Fructose Metabolism by PET - Journal of Nuclear Medicine
• Comparison of L-Threonine Aldolase Variants in the Aldol and Retro-Aldol Reactions - Frontiers
• Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development - Journal of Neuroscience
• A Type 1 Aldolase, NahE, Catalyzes a Stereoselective Nitro-Michael Reaction: Synthesis of β-Aryl-γ-nitrobutyric Acids - onlinelibrary.wiley.com
• Targeting a moonlighting function of aldolase induces apoptosis in cancer cells - Nature
• Structural insight into the unexploited allosteric binding site of fructose 1, 6-bisphosphate aldolase from C. albicans with α-lipoic acid - sciencedirect.com
• The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK - Nature
• An engineered aldolase enables the biocatalytic synthesis of 2′-functionalized nucleoside analogues - Nature
• Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1 - Nature
• Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect - Nature
• Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK - Nature
• The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair - Nature
• The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella - Nature
• Aldolase A: the broker of glycolysis - Nature
• Bioinformatics analysis of the role of aldolase A in tumor prognosis and immunity - Nature
• Aldolase B suppresses hepatocellular carcinogenesis by inhibiting G6PD and pentose phosphate pathways - Nature
• “Excited” Class I Aldolases: EDA Complex Mediated Photo-biocatalytic Enantioselective β-Alkylation of Enals - ACS Publications
• Promiscuity Guided Evolution of Decarboxylative Aldolases for Synthesis of Tertiary γ-Hydroxy Amino Acids - onlinelibrary.wiley.com
• Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase - Nature
• Evolution of a designed retro-aldolase leads to complete active site remodeling - Nature
• Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli - onlinelibrary.wiley.com
• Structure–Function Relationships between Aldolase C/Zebrin II Expression and Complex Spike Synchrony in the Cerebellum - Journal of Neuroscience
• Mutability-Landscape-Guided Engineering of l -Threonine Aldolase Revealing the Prelog Rule in Mediating Diastereoselectivity of C−C Bond Formation - onlinelibrary.wiley.com
• Fructose 1,6-bisphosphate aldolase/phosphatase may be an ancestral gluconeogenic enzyme - Nature
• Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite - PNAS
• Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase - Nature
• A Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates - onlinelibrary.wiley.com
• Aldolase A Accelerates Cancer Progression by Modulating mRNA Translation and Protein Biosynthesis via Noncanonical Mechanisms - Wiley
• Aldolase A and Phospholipase D1 Synergistically Resist Alkylating Agents and Radiation in Lung Cancer - Frontiers
• Crystal Structure and NMR of an α,δ-Peptide Foldamer Helix Shows Side-Chains are Well Placed for Bifunctional Catalysis: Application as a Minimalist Aldolase Mimic - onlinelibrary.wiley.com
• Characterization of a widespread sugar phosphate-processing bacterial microcompartment | Communications Biology - Nature
• Pyruvic oxime dioxygenase from heterotrophic nitrifier Alcaligenes faecalis is a nonheme Fe - Nature
• Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase - EurekAlert!
• Structural basis for the bifunctionality of fructose-1,6-bisphosphate aldolase/phosphatase - Nature
• A developmental biological study of aldolase gene expression in Xenopus laevis - Nature
• Trading off stability against activity in extremophilic aldolases - Nature
• Progress in Stereoselective Construction of C–C Bonds Enabled by Aldolases and Hydroxynitrile Lyases - Frontiers
• Porphyrin Excretion Resulting From Mutation of a Gene Encoding a Class I Fructose 1,6-Bisphosphate Aldolase in Rhodobacter capsulatus - Frontiers
• Inherited Metabolic Myopathy and Hemolysis Due to a Mutation in Aldolase A - NEJM
• Liver Cancer Growth Halted by Enzyme Blockade in Mice - Technology Networks
• Biocatalytic Synthesis of Aryl and Heteroaryl γ-Hydroxy-α-amino Acids via an Aldolase–Transaminase One-Pot Reaction | ACS Sustainable Chemistry & Engineering - ACS Publications
• Structure-based identification of a potential non-catalytic binding site for rational drug design in the fructose 1,6-biphosphate aldolase from Giardia lamblia - Nature
• One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse - Nature
• Molecular, Topographic, and Functional Organization of the Cerebellar Nuclei: Analysis by Three-Dimensional Mapping of the Olivonuclear Projection and Aldolase C Labeling - Journal of Neuroscience
• Aldolase Cascade Facilitated by Self-Assembled Nanotubes from Short Peptide Amphiphiles - onlinelibrary.wiley.com
• Recent Advances Regarding the Physiological Functions and Biosynthesis of D-Allulose - Frontiers
• DPDx - Diagnostic Procedures - Blood Specimens - Centers for Disease Control and Prevention | CDC (.gov)
• Characterization of FBA genes in potato (Solanum tuberosum L.) and expression patterns in response to light spectrum and abiotic stress - Frontiers
• Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution - PNAS
• Schematic Illustration of Fluorescence-Based Aldolase Assay (IMAGE) - EurekAlert!
• Cytoskeleton Crew - Harvard Medical School
• Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase - Medical Xpress
• Creation of a Tailored Aldolase for the Parallel Synthesis of Sialic Acid Mimetics - onlinelibrary.wiley.com
• A novel variant of the Calvin–Benson cycle bypassing fructose bisphosphate - Nature
• MS-based proteomic analysis of cardiac response to hypoxia in the goldfish ( Carassius auratus - Nature
• Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane - PNAS
• Form III RubisCO-mediated transaldolase variant of the Calvin cycle in a chemolithoautotrophic bacterium - PNAS