Why is "Aldosterone" trending?

Search Interest Perspective

• Aldosterone overload: An underappreciated contributor to high blood pressure - Harvard Health
• Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption - PLOS
• Aldosterone: The Forgotten Hormone - Medscape
• Aldosterone Synthase Inhibition for Hypertension - NEJM
• Aldosterone and the Mineralocorticoid Receptor in Atrial Fibrillation - American Heart Association Journals
• Different effect of aldosterone on corrected HCO3− across primary aldosteronism subtypes | Hypertension Research - Nature
• Exploring aldosterone: Blood pressure and disease insights - AstraZeneca
• New Drug Shows Promise in Treating a Common Cause of Hypertension - Northwestern University
• Plasma Aldosterone Measurement to Guide Prevention and Treatment of Heart Failure in Black Adults With Hypertension - JACC Journals
• Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction - NEJM
• Regulation of Aldosterone Secretion by Substance P and the Neurokinin Type 1 Receptor in Aldosterone‐Producing Adenomas - American Heart Association Journals
• Aldosterone–mineralocorticoid receptor interactions: new insights and therapeutic perspectives in primary aldosteronism - Nature
• Baxdrostat New Drug Application accepted under FDA Priority Review in the US for patients with hard-to-control hypertension - AstraZeneca
• Baxdrostat and the future of aldosterone-targeted therapy - Nature
• Renin-Angiotensin-Aldosterone System in Preeclampsia: Pathophysiological Insights and Links to Vascular Dementia - American Heart Association Journals
• Adrenal Aldosterone Synthase Expression Imaging in Primary Aldosteronism - NEJM
• Excess dietary potassium raises blood pressure in male mice by an aldosterone-dependent increase in ENaC - Nature
• Aldosterone-mediated hypertension and non-steroidal mineralocorticoid receptor antagonists - Nature
• Comparisons of renin-angiotensin-aldosterone levels measured by chemical luminescence immunoassay and liquid chromatography-tandem mass spectrometry in hypertensive patients under different pathophysiological conditions - Nature
• Elevated plasma aldosterone-to-renin ratio as a potential risk marker of adverse left ventricular remodeling: a cross-sectional study - Frontiers
• Somatic Mutations in MCOLN3 Are Associated With Aldosterone-Producing Adenomas - American Heart Association Journals
• Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density-Dependent Mechanisms in Aldosterone-Producing Adenomas - Wiley
• Diagnostic performance of 24-hour urinary aldosterone for primary aldosteronism in patients with or without discontinuation of antihypertensive medications - Nature
• Journal of Internal Medicine - Wiley Online Library
• Cardioprotective Effects of Finerenone Associated With the Suppression of Myocardial Sodium Accumulation in Aldosterone/Salt‐Loaded Rats - American Heart Association Journals
• Phase 2a Study of Baxdrostat in Primary Aldosteronism - NEJM
• New scan could help millions with hard-to-treat high blood pressure - UCL | University College London
• Combined effect of esaxerenone and dapagliflozin on aldosterone-mediated sodium reabsorption and potassium excretion - Frontiers
• Mixed Aldosterone and Cortisol Secretion in Patients with Adrenal Incidentalomas: Different Faces of the Old Concept of Connshing Syndrome - Cureus
• Anti-Aldosterone Myths Reassessed: - JACC Journals
• High salt intake exacerbates aldosterone-related target organ damage in patients with primary aldosteronism - Nature
• Development of Highly Selective Aldosterone Synthase Inhibitors - ACS Publications
• Age- and sex-specific reference intervals for renin and aldosterone in healthy individuals in Yunnan Province, China - Nature
• Histopathological spectrum of common aldosterone-driver gene mutations in aldosterone-producing adenomas - Frontiers
• Aldosterone-Producing Adrenal Oncocytoma: A Rare Cause of Primary Aldosteronism - Cureus
• Cosyntropin-Stimulated Aldosterone Reserve of the Nondominant Adrenal Predicts Surgical Outcomes in Primary Aldosteronism - American Heart Association Journals
• Novel drug tackles uncontrolled hypertension caused by aldosterone dysregulation - Medical Xpress
• Case Report: Anomalous drainage vein sampling for diagnosing aldosterone-producing lesions undetectable by segmental adrenal venous sampling in a two-case series - Frontiers
• Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension - NEJM
• Aldosterone in the brain and cognition: knowns and unknowns - Frontiers
• Blood pressure response to mineralocorticoid receptor antagonists or aldosterone synthase inhibitors according to baseline renin levels - Nature
• Aldosterone sensitivity: an opportunity to explore the pathogenesis of hypertension - American Physiological Society Journal
• Synergistic interplay between cortisol and aldosterone: unveiling mechanisms of vascular calcification in hyperaldosteronism - Nature
• Early Implementation of Aldosterone-Targeted Therapy in Patients With Hypertension - American Heart Association Journals
• The association between aldosterone and lipid profiles in patients with primary aldosteronism - Nature
• Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19 - NEJM
• Aldosterone breakthrough as a clue to the physiological importance of paracrine regulation of aldosterone secretion - Nature
• Fatty acid profiles in aldosterone-producing adenoma: insights into pathogenetic significance - Nature
• Effect of sodium-glucose cotransporter-2 inhibitors on aldosterone and renin levels in diabetes mellitus type 2 patients: a systematic review and meta-analysis - Nature
• Serum Aldosterone and the Incidence of Hypertension in Nonhypertensive Persons - NEJM
• Inhibition of aldosterone synthase: Does this offer advantages compared with the blockade of mineralocorticoid receptors? - Nature
• Efficacy and Safety of Aldosterone Synthase Inhibitors for Hypertension: A Meta-Analysis of Randomized Controlled Trials and Systematic Review - American Heart Association Journals
• Association of the trajectory of plasma aldosterone concentration with the risk of cardiovascular disease in patients with hypertension: a cohort study - Nature
• Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production - Nature
• Comparative analysis of aldosterone and renin assays for primary aldosteronism screening - Nature
• Poor sleep quality was associated with increased plasma aldosterone concentration in community dwellers, a cross-sectional study - Nature
• Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19 - NEJM
• Drug Effects on Aldosterone/Plasma Renin Activity Ratio in Primary Aldosteronism - American Heart Association Journals
• Endoscopic, ultrasound-guided, radiofrequency ablation of aldosterone-producing adenomas (FABULAS): a UK, multicentre, prospective, proof-of-concept trial - The Lancet
• Evaluating the role of aldosterone synthesis on adrenal cell fate - Frontiers
• Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial - The Lancet
• Effect of exercise training on the renin–angiotensin–aldosterone system: a meta–analysis - Nature
• Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands - PNAS
• Novel chemiluminescent immunoassay to measure plasma aldosterone and plasma active renin concentrations for the diagnosis of primary aldosteronism - Nature
• Characterization of the Renin-Angiotensin-Aldosterone System in Young Healthy Black Adults: The African Prospective Study on the Early Detection and Identification of Hypertension and Cardiovascular Disease (African-PREDICT Study) - American Heart Association Journals
• Adipocytes Produce Aldosterone Through Calcineurin-Dependent Signaling Pathways | Hypertension - American Heart Association Journals
• Aldosterone Synthase Inhibitors and Mineralocorticoid Receptor Antagonists: Competitors or Collaborators? - American Heart Association Journals
• Decreasing the Effects of Aldosterone in Resistant Hypertension — A Success Story - NEJM
• Aldosterone, a hormone that prevents dehydration, is linked to worsening kidney disease, study suggests - statnews.com
• Changes in aldosterone and obesity-related cardiometabolic risk factors with a 1-year weight loss intervention in normotensive overweight and obese young adults - Nature
• Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension - NEJM
• G protein–coupled estrogen receptor: a promising therapeutic target for aldosterone-induced hypertension - Frontiers
• Aldosterone-to-renin ratio is related to arterial stiffness when the screening criteria of primary aldosteronism are not met - Nature
• Renin-Angiotensin-Aldosterone Profiles in Pregnant Women With Chronic Hypertension - American Heart Association Journals
• Aldosterone and Vascular Mineralocorticoid Receptors: - American Heart Association Journals
• Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism - Nature
• Association Between Life's Simple 7 and Biomarkers of Cardiovascular Disease: Aldosterone, Interleukin ‐6, C‐Reactive Protein - American Heart Association Journals
• Aldosterone and angiotensin II profiles in young black and white women using different hormonal contraceptives: the African-PREDICT study | Journal of Human Hypertension - Nature
• Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19 - NEJM
• Aldosterone Receptor Antagonists: - American Heart Association Journals
• Predicting the laterality of the autonomous aldosterone production from adrenal vein sampling - Nature
• Role of ACTH and Other Hormones in the Regulation of Aldosterone Production in Primary Aldosteronism - Frontiers
• Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation - Nature
• A New Role for the Aldosterone/Mineralocorticoid Receptor Pathway in the Development of Mitral Valve Prolapse - American Heart Association Journals
• Genetic, Cellular, and Molecular Heterogeneity in Adrenals With Aldosterone-Producing Adenoma - American Heart Association Journals
• Association between the gut microbiome and the renin-angiotensin-aldosterone system: a possible link via the activation of the immune system - Nature
• Review of Markers of Zona Glomerulosa and Aldosterone-Producing Adenoma Cells - American Heart Association Journals
• Unrecognized hormonal condition may be contributing to high blood pressure - National Institutes of Health (.gov)
• RNA Sequencing Provides Novel Insights into the Transcriptome of Aldosterone Producing Adenomas - Nature
• A randomized vagus nerve stimulation study demonstrates that serum aldosterone levels decrease with age in women, but not in men - Nature
• The glucocorticoid receptor potentiates aldosterone-induced transcription by the mineralocorticoid receptor - PNAS
• Impact of gut microbiome on the renin-aldosterone system: Shika-machi Super Preventive Health Examination results - Nature
• A relationship between the aldosterone–mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans - Nature
• Aldosterone breakthrough from a pharmacological perspective - Nature
• Aldosterone in Congestive Heart Failure - NEJM
• Managing Hyperkalemia Caused by Inhibitors of the Renin–Angiotensin–Aldosterone System - NEJM
• Diagnosis and Localization of Aldosterone-Producing Adenomas by Adrenal-Vein Catheterization - NEJM
• Primary aldosteronism: The role of adrenal venous sampling - Mayo Clinic
• The selective aldosterone synthase inhibitor Baxdrostat significantly lowers blood pressure in patients with resistant hypertension - Frontiers
• Nongenomic Actions of Aldosterone on the Renal Tubule - American Heart Association Journals