Why is "Alpha-thalassemia" trending?

Search Interest Perspective

• Machine learning improves detection of alpha thalassemia carriers compared to clinical features - Nature
• UCLA scientists advance gene therapy for deadly blood disorder - Newsroom | UCLA
• Alpha-Thalassemia Unmasked in a Patient With Sickle Cell Trait: A Case Report - Cureus
• Luspatercept Data Expand Therapeutic Pathways in Alpha-Thalassemia - BioPharm International
• Luspatercept Meets Primary Endpoints in Phase 2 Alpha-Thalassemia Trial - HCPLive
• Bristol Myers Squibb Announces Positive Top-Line Results from Registrational Phase 2 Study of Luspatercept in Adults with Alpha (α)-Thalassemia - Yahoo Finance
• Bristol unveils positive phase 2 data for Reblozyl in alpha thalassemia - MSN
• Bristol Myers Squibb’s Reblozyl meets trial goals for alpha-thalassemia - Investing.com
• FDA Approves Milestone Oral Therapy for Adults With Thalassemia, Anemia - Pharmacy Times
• α-Thalassemia has no association with asymptomatic Plasmodium falciparum carriage in three ecological zones of Ghana - Nature
• Sickle Cell Disease in Oman: Lessons for the Rest of the World - Medscape
• Mitapivat in adults with non-transfusion-dependent α-thalassaemia or β-thalassaemia (ENERGIZE): a phase 3, international, randomised, double-blind, placebo-controlled trial - The Lancet
• Diagnostic Limitations of Hemoglobin A1c in the Setting of Compound Hemoglobinopathy: A Case Report of Sickle Cell Disease, Alpha Thalassemia, and Occult Diabetes - Cureus
• FDA Approves Mitapivat for Thalassemia-Related Anemia - MedPage Today
• Screening for Neonatal Hemoglobinopathies: Improvement Needed - Hematology Advisor
• FDA Approves Mitapivat for Transfusion-Dependent and Non-Transfusion-Dependent Alpha- and Beta-Thalassemia - HCPLive
• Assessing Bristol Myers Squibb (BMY) Valuation After Key Multiple Myeloma And Alpha Thalassemia Updates - Yahoo Finance
• Development and validation of an interpretable risk prediction model for the early classification of thalassemia - Nature
• Thalassemia Treatment Market to Witness Significant Growth by 2034 Driven by Novel Drug Development | DelveInsight - Yahoo Finance
• Multiclass classification of thalassemia types using complete blood count and HPLC data with machine learning - Nature
• Unexpectedly Low HbA1c in a Patient With Newly Diagnosed Diabetes Mellitus and Thalassemia Trait: A Case Report - Cureus
• A comprehensive case study of deep learning on the detection of alpha thalassemia and beta thalassemia using public and private datasets - Nature
• Hemoglobinopathies and iron deficiency among Northeast-Thai blood donors deferred for low hemoglobin - Nature
• New FDA-approved pill targets anemia in adults with alpha or beta thalassemia - Stock Titan
• White matter microstructure abnormalities in thalassemia patients using TBSS analysis based on DTI - Nature
• Gene Therapy Could End Lifelong Transfusions For Rare Blood Disorder - Forbes
• USFDA Approves Agios Pharma's Aqvesme for Alpha, Beta Thalassemia Anemia - Medical Dialogues
• Avanzanite Bioscience’s Partner Agios Announces Positive CHMP Opinion for PYRUKYND® (mitapivat) for Adults with Thalassemia - Business Wire
• With a boost from beta, alpha thalassemia gene therapies blossom - Drug Discovery News
• Newborn Screening Practices and Alpha-Thalassemia Detection — United States, 2016 | MMWR - Centers for Disease Control and Prevention | CDC (.gov)
• Establishment of an α-thalassemia mouse model through fetal liver cell transplantation and analysis of hematological parameters - Nature
• Pregnancy outcomes in women affected by fetal alpha-thalassemia: a case control study - Nature
• Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA - Nature
• Revisiting and updating molecular epidemiology of α-thalassemia mutations in Thailand using MLPA and new multiplex gap-PCR for nine α-thalassemia deletion - Nature
• Alpha-thalassemia - Genetics in Medicine - Nature
• Chinese Scientists Use Gene Therapy to Cure Thalassemia in Children - Sixth Tone
• Natera introduces prenatal test for detecting inherited conditions - Medical Device Network
• Forager and farmer evolutionary adaptations to malaria evidenced by 7000 years of thalassemia in Southeast Asia - Nature
• Disease burden, management strategies, and unmet needs in α-thalassemia due to hemoglobin H disease - Wiley Online Library
• In Utero Transfusions Support Improved Survival in Patients With Alpha Thalassemia Major - Hematology Advisor
• Feeling tired or weak? It may be due to alpha thalassemia - Healthshots
• The α-Thalassemias - NEJM
• Zeta Globin Gene Expression May Lead to Therapy for Alpha Thalassemia Major - Docwire News
• Lentiviral gene transfer improves human alpha globin production for the treatment of alpha thalassemia - Medical Xpress
• Genetic origin of α0-thalassemia (SEA deletion) in Southeast Asian populations and application to accurate prenatal diagnosis of Hb Bart’s hydrops fetalis syndrome | Journal of Human Genetics - Nature
• Personal Story: Robert Mannino | Thalassemia - Centers for Disease Control and Prevention | CDC (.gov)
• Natural history of alpha-thalassemia X-linked intellectual disability syndrome: A case report of a 45-year-old man - Wiley Online Library
• Sickle Trait and Alpha Thalassemia Increase NOS-Dependent Vasodilation of Human Arteries Through Disruption of Endothelial Hemoglobin-eNOS Interactions - American Heart Association Journals
• Alpha Thalassemia/Mental Retardation Syndrome X-Linked, the Alternative Lengthening of Telomere Phenotype, and Gliomagenesis: Current Understandings and Future Potential - Frontiers
• Mitapivat Induces Responses in Patients With Thalassemia - Hematology Advisor
• Sickle cell, thalassemia, and heat: risk estimates and equity policy considerations from an exploratory timeseries study in California - medRxiv
• Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia - Nature
• The α-Thalassemias - NEJM
• Analysis of rare thalassemia genetic variants based on third-generation sequencing - Nature
• Development and clinical validation of a novel detection kit for α-thalassemia in southern Chinese - Frontiers
• Thalassaemia - The Lancet
• Molecular Characterization Analysis of Thalassemia and Hemoglobinopathy in Quanzhou, Southeast China: A Large-Scale Retrospective Study - Frontiers
• Miracle baby fights on with Alpha Thalassemia Major - cbs8.com
• What to Know About Thalassemia and COVID-19 - Verywell Health
• Hydrops Fetalis with Alpha Thalassemia - NEJM
• Genotyping of high homology HBA1 and HBA2 from Illumina whole-genome sequencing - Illumina
• Unusual survival of a twin with homozygous α0-thalassemia due to chimerism - Haematologica
• Analysis of genotype–phenotype correlation in patients with α-thalassemia from Fujian province, Southeastern China - Wiley Online Library
• The genetic architecture of the β-globin chain in individuals with and without sickle cell disease in Nigeria: A case for beta thalassemia? - medRxiv
• Molecular characterization of thalassemia and hemoglobinopathy in Southeastern China - Nature
• “Double-hit” ineffective erythropoiesis—concurrent β-thalassemia with α-gene triplication and myelodysplastic syndrome with SF3B1 mutation - Wiley Online Library
• The pleiotropic effects of α-thalassemia on HbSS and HbSC sickle cell disease: Reduced erythrocyte cation co-transport activity, serum erythropoietin, and transfusion burden, do not translate into increased survival - Wiley Online Library
• OBGYN - Wiley
• Addressing Gaps in Care for Patients With Thalassemia - Hematology Advisor
• The molecular spectrum and distribution of haemoglobinopathies in Cyprus: a 20-year retrospective study - Nature
• Thalassemia is a silent genetic disorder that can be prevented through awareness and screening - The Statesman
• Non‐Transfusion‐Dependent Thalassemia: An Image Gallery Worth a Thousand Words - Wiley Online Library
• Pseudothrombocytosis due to small misshapen RBC and fragmented RBC in coexistence of beta thalassemia minor and secondary elliptocytosis - Wiley Online Library
• Patients welcome introduction of the National Blood Transfusion Bill, 2025 - The Hindu
• Diagnosis of α-thalassaemia by colorimetric gap loop mediated isothermal amplification - Nature
• A novel telomeric (~285 kb) α-thalassemia deletion leading to a phenotypically unusual HbH disease - Haematologica
• British Journal of Haematology - Wiley Online Library
• Case report: First report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia - Frontiers
• Quantitative evaluation of the clinical severity of hemoglobin H disease in a cohort of 591 patients using a scoring system based on regression analysis - Haematologica
• Beta thalassaemia intermedia due to co-inheritance of three unique alpha globin cluster duplications characterised by next generation sequencing analysis - Wiley Online Library
• World Thalassemia Day: Know the best diet for thalassemia - Healthshots
• Alpha-Beta Thalassemia Disease in a Negro Family - NEJM
• The pleiotropic effects of α-thalassemia on HbSS and HbSC sickle cell disease: Reduced erythrocyte cation co-transport activity, serum erythropoietin, and transfusion burden, do not translate into increased survival - Wiley Online Library
• Fetal gene therapy of α-thalassemia in a mouse model - PNAS
• The value of single-molecule real-time technology in the diagnosis of rare thalassemia variants and analysis of phenotype–genotype correlation | Journal of Human Genetics - Nature
• White Matter Changes and Headache in Thalassemia - Hematology Advisor
• Alpha-globin gene cluster haplotypes and D1S80, D17S5, and TPO VNTR polymorphisms among four ethnic populations from lower northeastern Thailand | Scientific Reports - Nature
• The pedigree analysis and prenatal diagnosis of Hong Kongαα Thalassemia and the sequence analysis of Hong Kongαα Allele - Wiley Online Library
• -thalassemia ameliorate thalassemia severity when co-inherited with α-thalassemia - Nature
• Over 3,000 Thalassemia cases recorded in the Kurdistan Region amid growing alarm - rudaw.net
• Analysis of thalassemia genotypes and HbA2 test results in pregnant women in Shenzhen, China - Nature
• Familial Mediterranean fever with a single MEFV mutation: can a deletion resulting in α-thalassemia be the cause? - Nature
• Significance of genetic modifiers of hemoglobinopathies leading towards precision medicine - Nature
• Molecular analysis of alpha- and beta-thalassemia in Meizhou region and comparison of gene mutation spectrum with different regions of southern China - Wiley Online Library
• A novel gap-PCR with high resolution melting analysis for the detection of α-thalassaemia Southeast Asian and Filipino β0-thalassaemia deletion | Scientific Reports - Nature
• Case Report: The third-generation sequencing confirmed a novel 7.2 Kb deletion at β-globin gene in a patient with rare β-thalassemia - Frontiers
• Myelodysplastic syndrome associated with acquired beta thalassemia: “BTMDS” - Wiley Online Library
• Applications of next generation sequencing in the screening and diagnosis of thalassemia: A mini-review - Frontiers
• Premarital screening for thalassemia and sickle cell disease in Saudi Arabia - Nature
• Hepatocellular carcinoma as an emerging morbidity in the thalassemia syndromes: A comprehensive review - Wiley