Why is "Alport syndrome" trending?

Search Interest Perspective

• ‘Missing’ disease-causing variants in Alport syndrome - Nature
• Q&A: Managing Pregnancy in Patients With Alport Syndrome - Physician's Weekly
• Alport syndrome complicated with IgA nephropathy: a case report - Frontiers
• Bayer begins phase 2 trial of new Alport syndrome therapy - PharmaTimes
• Calliditas Therapeutics Reports Safety Data for Setanaxib in Patients with Alport Syndrome at the American Society of Nephrology Kidney Week - PR Newswire
• Autosomal Dominant Alport Syndrome Diagnosed in an Elderly Man - Cureus
• Bayer takes Alport syndrome drug into phase 2 - pharmaphorum
• Alport Syndrome Outcomes Linked to Genotype and Proteinuria in RaDaR Study - HCPLive
• Evotec-Partner Bayer Starts Phase 2 Study for Treatment of Patients with Alport Syndrome - Yahoo Finance
• Women with Alport syndrome may face greater infertility, pregnancy risks - Healio
• Psychotic Disorder and Alport: Complex Presentation of Related Illnesses? - Psychiatry Online
• Clinical features of hearing loss and genotype–phenotype correlations in Alport syndrome caused by COL4A4 or COL4A5 variants - Nature
• An Elusive Diagnosis of Autosomal Dominant Alport Syndrome: Genomic Sequencing Is a Game Changer - Cureus
• Case Report: Neuroretinitis versus hypertensive retinopathy secondary to Alport syndrome - Frontiers
• Collagen IV in Gould syndrome and Alport syndrome - Nature
• Bilateral giant macular holes in a patient with Alport syndrome - Nature
• Novel COL4A3 COL4A5 variants and digenic inheritance in pediatric Alport syndrome from Southwestern China - Nature
• A novel mouse model for X-linked Alport syndrome induced by splicing mutation in the Col4a5 gene - Nature
• ENYO Pharma Announces Completion and Topline Data From Phase 2 Alpestria-1 Clinical Study in Alport Syndrome Demonstrating Vonafexor Reverses Kidney Function Decline and Has Sustained Therapeutic Benefit - Business Wire
• Case Report: Whole genome sequencing identifies a novel deep intronic COL4A5 variant of uncertain significance in X-linked Alport syndrome - Frontiers
• Why do patients with Alport Syndrome lose their hearing? - Kidney Research UK
• Alport Syndrome Pipeline 2026: FDA Updates, Therapy - openPR.com
• Proteinuria in Alport Syndrome: Treatment With Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitors - Cureus
• The heterozygous mutation COL4A4 c.817-1G>A causes Alport syndrome in a Chinese family: a case report - Frontiers
• SonoThera Presents New Data at ASN Kidney Week 2025 Demonstrating Full-Length Col4a5 Gene Expression Using Ultrasound Mediated Gene Delivery in Treating X-Linked Alport Syndrome - BioSpace
• ENYO Pharma Announces Completion of Series C Financing With Vesalius Biocapital and Continued Progress of Its ALPESTRIA-1 Clinical Phase 2 Study in Alport Syndrome Patients - BioSpace
• Norfolk man with rare genetic disease in need of a kidney - 13newsnow.com
• Catching Alport syndrome through universal age-3 urine screening - kobe-u.ac.jp
• Evaluation of Anterior Lenticonus in Alport Syndrome Using Tracey Wavefront Aberrometry and Transmission Electron Microscopy - Healio
• Bayer begins Phase IIa trial of BAY 3401016 for Alport Syndrome - Medical Dialogues
• Alport Syndrome: Practice Essentials, Background, Pathophysiology and Etiology - Medscape
• Gloucestershire woman to raise funds with 125 mile walk for kidney charities - Punchline-Gloucester.com
• The 2019 and 2021 International Workshops on Alport Syndrome - Nature
• Slowly progressive autosomal dominant Alport Syndrome due to COL4A3 splicing variant - Nature
• The Alport Syndrome Clinic - School of Medicine | University of Utah
• Metformin ameliorates the severity of experimental Alport syndrome - Nature
• Rare Dual Diagnosis: Alport Syndrome and Immune Complex-Mediated MPGN Coexist in the Same Patient - Medical Dialogues
• Alport syndrome: A puzzling case of thrombocytopenia and giant unusual platelets in blood smear - onlinelibrary.wiley.com
• Facing kidney failure again, two years after my life-changing transplant - Kidney Research UK
• Study aims to research genetic therapies for Alport syndrome - The University of Manchester
• Mouse study shows potential of gene therapy for Alport syndrome - WashU Medicine
• Genotype–phenotype correlation of X-linked Alport syndrome observed in both genders: a multicenter study in South Korea | Scientific Reports - Nature
• iPSC-derived type IV collagen α5-expressing kidney organoids model Alport syndrome - Nature
• Case report: A case report of Alport syndrome caused by a novel mutation of COL4A5 - Frontiers
• Creation of X-linked Alport syndrome rat model with Col4a5 deficiency - Nature
• Consensus statement on standards and guidelines for the molecular diagnostics of Alport syndrome: refining the ACMG criteria - Nature
• Uniting to meet the challenge of Alport syndrome - Kidney Research UK
• Development of an exon skipping therapy for X-linked Alport syndrome with truncating variants in COL4A5 - Nature
• Glomerular endothelial cell heterogeneity in Alport syndrome - Nature
• J.P. Morgan Healthcare Conference to Advance Multiple Genetic Medicine Programs Toward First-in-Human Studies - Business Wire
• Pathogenic variants of Alport syndrome and monogenic diabetes identified by exome sequencing in a family - Nature
• A founder COL4A3 pathogenic variant resulting in Alport syndrome and thin basement membrane disease: a case report series - Frontiers
• A novel COL4A5 splicing variant causing X-linked Alport syndrome: A case report - Nature
• Synaptopodin deficiency exacerbates kidney disease in a mouse model of Alport syndrome - journals.physiology.org
• Editorial: Collagen IV nephropathies: Alport syndrome and beyond - Frontiers
• Novel heterozygous mutation in COL4A4 responsible for Alport syndrome in a Chinese family - Frontiers
• Pregnancy and Alport syndrome - Kidney Research UK
• New frontiers to cure Alport syndrome: COL4A3 and COL4A5 gene editing in podocyte-lineage cells - Nature
• Case report: Unilateral panuveitis as a manifestation of Alport syndrome in a Chinese pediatric patient - Frontiers
• Case report: Preimplantation genetic testing for X-linked alport syndrome caused by variation in the COL4A5 gene - Frontiers
• Focusing on the eye signs of Alport syndrome in a 40-year-old man who previously had a kidney transplant and hearing loss - The Lancet
• Case Report: Nephrotic syndrome as the primary manifestation of Alport syndrome in a Chinese pediatric patient - Frontiers
• Ocular Manifestations of Alport Syndrome: Report and Comparison of Two Cases - Cureus
• Pathogenic variants in the Alport genes are prevalent in the Singapore multiethnic population with highest frequency in the Chinese - Nature
• Angiotensin-[1–7] attenuates kidney injury in experimental Alport syndrome - Nature
• Case report: A novel compound heterozygous variant in the COL4A3 gene was identified in a patient with autosomal recessive Alport syndrome - Frontiers
• Molecular and Cellular Mechanisms Underlying the Initiation and Progression of Alport Glomerular Pathology - Frontiers
• The adventurer who confronted his fears to raise awareness of Alport syndrome - Kidney Research UK
• Type A Dissection in a Patient With Alport Syndrome - American Heart Association Journals
• Dr. Alessia Fornoni Receives Grants to Study Alport Syndrome - University of Miami
• ON TREND | Alport Syndrome Awareness: Hearing Loss Caused by Kidney Disease - American Academy of Audiology
• Eloxx reports all patients in Phase II Alport syndrome trial have improved - Clinical Trials Arena
• SGLT2 Inhibition in Young Patients with Alport Syndrome, with Oliver Gross, MD - HCPLive
• S1PR4 inhibition prevents disease progression in murine Alport syndrome - BioWorld MedTech
• mRNA analysis identifies deep intronic variants causing Alport syndrome and overcomes the problem of negative results of exome sequencing - Nature
• K-SOTTO’s timely intervention through kidney transplantation saves life of boy suffering from Alport Syndrome - The New Indian Express
• High-flow arteriovenous fistula in X-linked Alport syndrome: a case report - Frontiers
• Clinical Features and Familial Mutations in an Autosomal-Inherited Alport Syndrome Patient With the Presentation of Nephrotic Syndrome - Frontiers
• Pathogenicity of missense variants affecting the collagen IV α5 carboxy non-collagenous domain in X-linked Alport syndrome - Nature
• Clinical Manifestations of Alport Syndrome-Diffuse Leiomyomatosis Patients With Contiguous Gene Deletions in COL4A6 and COL4A5 - Frontiers
• Alport Syndrome Market to Witness Upsurge in Growth at a Massive CAGR of 69% by 2034 | DelveInsight - PR Newswire
• Alport Syndrome With a Rare Collagen Type IV Alpha-4 (COL4A4) Gene Mutation: A Case Report - Cureus
• Retinal Pathology Linked to Nephropathy in Alport Syndrome - ARVO Journals
• Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background - Nature
• AI-based method shows promise for pathological diagnosis of hereditary kidney diseases - Medical Xpress
• Identification of novel COL4A5 variants and prenatal diagnosis in three large families - Nature
• Alport's Syndrome, Goodpasture's Syndrome, and Type IV Collagen - nejm.org
• Harnessing mechanobiology to combat kidney disease - WashU
• In limbo: father and daughter await kidney transplants - Berthoud Weekly Surveyor
• Characterization of contiguous gene deletions in COL4A6 and COL4A5 in Alport syndrome-diffuse leiomyomatosis - Nature
• SGLT2 Inhibition May Reduce Albuminuria in Young Patients with Alport Syndrome - HCPLive
• The Contribution of COL4A5 Splicing Variants to the Pathogenesis of X-Linked Alport Syndrome - Frontiers
• Eloxx Pharmaceuticals begins subject dosing in Alport syndrome therapy trial - Clinical Trials Arena
• Alport syndrome severity can be predicted by causative protein genotype - Medical Xpress
• Fibrocor Therapeutics collaborates with MSRD to advance candidate for Alport syndrome - BioWorld MedTech
• Calliditas starts Phase II trial for rare kidney disease therapy - Clinical Trials Arena
• Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments - News-Medical
• Case Report: Identification of a Novel Heterozygous Missense Mutation in COL4A3 Gene Causing Variable Phenotypes in an Autosomal-Dominant Alport Syndrome Family - Frontiers
• COL4A6 is dispensable for autosomal recessive Alport syndrome - Nature
• FDA Panel Votes on Bardoxolone for CKD Caused by Alport Syndrome - empr.com