Why is "Amelogenesis" trending?
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Trend Analysis
- Ranking position: #
- Date: 2026-03-18 01:07:45
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
Amelogenesis is the process of forming tooth enamel, the hard, protective outer layer of teeth. This process begins during tooth development after the initial formation of dentin (dentinogenesis), the layer beneath the enamel. The inner enamel epithelium (IEE), a layer of cells within the developing tooth, plays a crucial role by signaling the differentiation of specialized cells called ameloblasts, which then secrete the proteins and minerals that make up enamel. The formation of dentin is essential for amelogenesis to occur, and a reciprocal signaling process between the developing dentin and the IEE-derived ameloblasts ensures the proper coordination of these two crucial stages of tooth development.
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Trending Topic Today
Search Interest Perspective
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Amelogenesis Imperfecta and Epilepsy - Neurology® Journals
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Craniofacial Radiographic Features in Amelogenesis Imperfecta: A Case-Control Study - Cureus
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Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease - Nature
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Orthodontic management of amelogenesis imperfecta: A case report - Wiley Online Library
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Case Report: Crown Resorption in a Patient With Junctional Epidermolysis Bullosa and Amelogenesis Imperfecta With LAMB3 Gene Mutations - Frontiers
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Novel FAM83H mutations in patients with amelogenesis imperfecta - Nature
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Etiology, Classification, and Restorative Management of Amelogenesis Imperfecta Among Children and Young Adults: A Scoping Review - Cureus
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Molecular‐based phenotype variations in amelogenesis imperfecta - Dong - 2023 - Oral Diseases - Wiley Online Library
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MAST4 regulates stem cell maintenance with DLX3 for epithelial development and amelogenesis - Nature
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Mutations in RELT cause autosomal recessive amelogenesis imperfecta - Kim - 2019 - Clinical Genetics - Wiley Online Library
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Oro-dental phenotyping and report of three families with RELT -associated amelogenesis imperfecta - Nature
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Genetic testing for amelogenesis imperfecta: knowledge and attitudes of paediatric dentists - Nature
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SLC10A7 mutations cause a skeletal dysplasia with amelogenesis imperfecta mediated by GAG biosynthesis defects - Nature
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Orthodontic bonding in special circumstances - Nature
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Identification of the C-terminal region in Amelogenesis Imperfecta causative protein WDR72 required for Golgi localization - Nature
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Amelogenesis imperfecta: the inside story - British Dental Journal - Nature
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MiR-153 Regulates Amelogenesis by Targeting Endocytotic and Endosomal/lysosomal Pathways–Novel Insight into the Origins of Enamel Pathologies - Nature
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Abrogation of epithelial BMP2 and BMP4 causes Amelogenesis Imperfecta by reducing MMP20 and KLK4 expression - Nature
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Loss of epithelial FAM20A in mice causes amelogenesis imperfecta, tooth eruption delay and gingival overgrowth - Nature
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Amelogenesis imperfecta - lifelong management. Restorative management of the adult patient - Nature
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Defects in the acid phosphatase ACPT cause recessive hypoplastic amelogenesis imperfecta - Nature
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The interdisciplinary management of patients with amelogenesis imperfecta – restorative dentistry - Nature
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Stable Isotopes Reveal Rapid Enamel Elongation (Amelogenesis) Rates for the Early Cretaceous Iguanodontian Dinosaur Lanzhousaurus magnidens - Nature
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Amelogenesis Imperfecta with Nephrocalcinosis: A Rare Association in Siblings - Cureus
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Patient-reported outcome measure for children and young people with amelogenesis imperfecta | British Dental Journal - Nature
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RETRACTED ARTICLE: Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis - Nature
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Partial Amelogenesis Imperfecta: A Report of a Rare Case - Cureus
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Full-mouth rehabilitation choices depending on amelogenesis imperfecta's type: A familial case report - Wiley Online Library
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Interdisciplinary full mouth rehabilitation of a patient with amelogenesis imperfecta from childhood to young adult-hood: A 12-year case report - Wiley Online Library
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The role of the TGF-β1 signaling pathway in the process of amelogenesis - Frontiers
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Amelogenesis Imperfecta: Rehabilitation and Brainstorming on the Treatment Outcome after the First Year - Wiley Online Library
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Digenic inheritance accounts for phenotypic variability in amelogenesis imperfecta - Yang - 2024 - Clinical Genetics - Wiley Online Library
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The Unfolded Protein Response in Amelogenesis and Enamel Pathologies - Frontiers
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An Interdisciplinary Approach to the Treatment of Amelogenesis Imperfecta - Dentistry Today
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Specialist and transitional care provision for amelogenesis imperfecta: a UK-wide survey | British Dental Journal - Nature
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The circadian clock in enamel development - Nature
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Jalili syndrome: retinal dystrophy and amelogenesis imperfecta: genotype-phenotype analysis in four new cases - ARVO Journals
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Noninvasive and Multidisciplinary Approach to the Functional and Esthetic Rehabilitation of Amelogenesis Imperfecta: A Pediatric Case Report - Wiley Online Library
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Managing vertical dimensions in patients with Amelogenesis Imperfecta: A case report - Wiley Online Library
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Full Mouth Rehabilitation Using the Twin Stage Procedure in a Patient with Amelogenesis Imperfecta: A Case Report - Cureus
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Erratum: Cone-rod dystrophy and amelogenesis imperfecta (Jalili syndrome): phenotypes and environs - Nature
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A novel FAM83H variant causes familial amelogenesis imperfecta with incomplete penetrance - Wiley Online Library
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Oral Rehabilitation Of Two Patients With Amelogenesis Imperfecta - Oral Health Group
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The crucial role of the TRPM7 kinase domain in the early stage of amelogenesis - Nature
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Rehabilitation of a patient with amelogenesis imperfecta and severe open bite: A multidisciplinary approach - Wiley Online Library
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Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice - Frontiers
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Amelogenesis Imperfecta and Screening of Mutation in Amelogenin Gene - Oliveira - 2014 - Case Reports in Dentistry - Wiley Online Library
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Amelogenesis imperfecta with Class III malocclusion, reduced crown size and decreased OVD: A multi‐disciplinary management and a 5‐year follow‐up - Labidi - 2020 - Clinical Case Reports - Wiley Online Library
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Amelogenic transcriptome profiling in ameloblast-like cells derived from adult gingival epithelial cells - Nature
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TGF-β1 autocrine signalling and enamel matrix components - Nature
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Mobility gene expression differences among wild-type, Mmp20 null and Mmp20 over-expresser mice plus visualization of 3D mouse ameloblast directional movement - Nature
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Aesthetic and Functional Rehabilitation of the Primary Dentition Affected by Amelogenesis Imperfecta - Wiley Online Library
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A suitable method - Nature
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Meeting report: a hard look at the state of enamel research | International Journal of Oral Science - Nature
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Whole-exome sequencing, without prior linkage, identifies a mutation in LAMB3 as a cause of dominant hypoplastic amelogenesis imperfecta - Nature
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Enamel defects in Acp4R110C/R110C mice and human ACP4 mutations - Scientific Reports - Nature
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Protein nanoribbons template enamel mineralization - PNAS
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Special feature: Gene genie - Nature
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Identification of a locus on chromosome 2q11 at which recessive amelogenesis imperfecta and cone-rod dystrophy cosegregate - Nature
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Cone-rod dystrophy and amelogenesis imperfecta (Jalili syndrome): phenotypes and environs - Nature
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Discovered: the earliest known common genetic condition in human evolution - The Conversation
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MMP20-generated amelogenin cleavage products prevent formation of fan-shaped enamel malformations - Nature
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Disruption of Steroid Axis, a New Paradigm for Molar Incisor Hypomineralization (MIH) - Frontiers
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A link between autoimmune disorders and tooth enamel defects revealed - Akademie věd
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Atomic-scale compositional mapping reveals Mg-rich amorphous calcium phosphate in human dental enamel - Science | AAAS
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.