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Amelogenesis imperfecta (AI) is a group of congenital disorders, involving the abnormal formation of tooth enamel, the external layer of the crown of teeth. Amelogenesis imperfecta can be unrelated to any systemic or generalized conditions or can be part of a syndromic condition. Healthy, fully formed enamel is approximately 96% mineral by weight and forms over months to years in humans, depending upon the tooth in question.
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