Why is "Aminolevulinic acid" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-19 10:10:03
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
δ-Aminolevulinic acid, an endogenous non-proteinogenic amino acid, is the first compound in the porphyrin synthesis pathway, the pathway that leads to heme in mammals, as well as chlorophyll in plants.
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Trending Topic Today
Search Interest Perspective
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FDA Accepts sNDA Filing of Aminolevulinic Acid Topical Gel for Superficial Basal Cell Carcinoma - OncLive
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Evaluation of Telomerase Reverse Transcriptase (TERT) Promoter Mutations in Photodynamic Diagnosis With 5-Aminolevulinic Acid False-Positive Sites in Non-muscle-Invasive Bladder Cancer - Cureus
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NX Development Corp Submits Supplemental New Drug Application to FDA for MEN-301 Study - Columbus Ledger-Enquirer
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Sun Pharma Canada Inc. Acquires Commercial Rights to LEVULAN® KERASTICK® - BioSpace
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sNDA for Aminolevulinic Acid Gel Plus PDT in sBCC Is Submitted to the FDA - OncLive
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Biofrontera Inc. Announces Patent for Propylene Glycol-Free Formula of Ameluz® (aminolevulinic acid HCI) Topical Gel, 10% Now Listed in FDA Orange Book - Yahoo Finance
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Biofrontera Completes Ameluz Phase 2b Trial for Moderate to Severe Acne - Dermatology Times
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Cancer stem cell populations are resistant to 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT) - Nature
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Normal reference ranges for urinary δ‐aminolevulinic acid and porphobilinogen levels - Agarwal - 2021 - JIMD Reports - Wiley Online Library
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Application of 5-aminolevulinic acid promotes ripening and accumulation of primary and secondary metabolites in postharvest tomato fruit - Frontiers
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Fox Chase Researcher Presents Findings on 5-Aminolevulinic Acid-Mediated Radiation Therapy to Reduce Tumor Size at American Society for Radiation Oncology Meeting - Fox Chase Cancer Center
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Q&A: Rolf-Markus Szeimies, MD, on the Evolution of 5-ALA - Dermatology Times
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5-Aminolevulinic acid overcomes hypoxia-induced radiation resistance by enhancing mitochondrial reactive oxygen species production in prostate cancer cells | British Journal of Cancer - Nature
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Exogenously applied 5-aminolevulinic acid modulates growth, yield, and physiological parameters in lentil ( Lens culinaris Medik.) under rain-fed and supplemental irrigation conditions - Nature
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Repeated 5-aminolevulinic acid mediated sonodynamic therapy using magnetic resonance guided focused ultrasound in rat brain tumour models - Nature
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5-aminolevulinic acid-mediated photodynamic therapy can target aggressive adult T cell leukemia/lymphoma resistant to conventional chemotherapy - Nature
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Effects of 5-aminolevulinic acid and sodium ferrous citrate on fibroblasts from individuals with mitochondrial diseases - Nature
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MR-guided Focused Ultrasound Facilitates Sonodynamic Therapy with 5-Aminolevulinic Acid in a Rat Glioma Model - Nature
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5-Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapy - Nature
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5-Aminolevulinic Acid Guided Sampling of Glioblastoma Microenvironments Identifies Pro-Survival Signaling at Infiltrative Margins - Nature
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5-aminolevulinic acid might help fight mitochondrial disorders - EurekAlert!
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Antitumor immunostimulatory effect via cell-killing action of a novel extracorporeal blood circulating photodynamic therapy system using 5-aminolevulinic acid - Nature
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Evaluation of Aminolevulinic Acid-Derived Tumor Fluorescence Yields Disparate Results in Murine and Spontaneous Large Animal Models of Lung Cancer - Nature
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5-aminolevulinic acid induced photodynamic reactions in diagnosis and therapy for female lower genital tract diseases - Frontiers
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Systemic MEK inhibition enhances the efficacy of 5-aminolevulinic acid-photodynamic therapy - Nature
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Enhancement of 5-aminolevulinic acid-based fluorescence detection of side population-defined glioma stem cells by iron chelation - Nature
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A New Strategy for Production of 5-Aminolevulinic Acid in Recombinant Corynebacterium glutamicum with High Yield - ASM Journals
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Optimization of the heme biosynthesis pathway for the production of 5-aminolevulinic acid in Escherichia coli - Nature
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Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’ - Frontiers
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AUA 2024: Diagnostic Performance of Fluorescence Cystoscopy Using Oral 5-Aminolevulinic Acid in Transurethral Resection of Bladder Tumor After BCG Treatment - UroToday
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Metronomic photodynamic therapy using an implantable LED device and orally administered 5-aminolevulinic acid - Nature
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Reduction of fatigue and anger-hostility by the oral administration of 5-aminolevulinic acid phosphate: a randomized, double-blind, placebo-controlled, parallel study - Nature
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5-Aminolevulinic Acid Multispectral Imaging for the Fluorescence-Guided Resection of Brain Tumors: A Prospective Observational Study - Frontiers
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Modified 5-aminolevulinic acid photodynamic therapy suppresses cutaneous squamous cell carcinoma through blocking Akt/mTOR-mediated autophagic flux - Frontiers
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Metal-Organic Layer Delivers 5-Aminolevulinic Acid and Porphyrin for Dual-Organelle-Targeted Photodynamic Therapy - Wiley Online Library
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Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid - Nature
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Enhanced lipid metabolism induces the sensitivity of dormant cancer cells to 5-aminolevulinic acid-based photodynamic therapy - Nature
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5-Aminolevulinic Acid Fluorescence-Guided Surgery in Head and Neck Squamous Cell Carcinoma - Wiley Online Library
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Growth regulator 5-aminolevulinic acid enhances the cold resistance of tomato plants - Phys.org
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Photosensitivity Reaction From Operating Room Lights After Oral Administration of 5-Aminolevulinic Acid for Fluorescence-Guided Resection of a Malignant Glioma - Cureus
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Glutaminase 2 expression is associated with regional heterogeneity of 5-aminolevulinic acid fluorescence in glioblastoma - Nature
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Application of 5-aminolevulinic acid-mediated Waterlase-assisted photodynamic therapy in the treatment of oral leukoplakia - Nature
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5-aminolevulinic acid: enhancing tomato resilience against cold stress | Newswise - Newswise
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5-Aminolevulinic Acid Hydrochloride Market - Market.us
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Comparison between intravesical and oral administration of 5-aminolevulinic acid in the clinical benefit of photodynamic diagnosis for nonmuscle invasive bladder cancer - Wiley
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Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy - Nature
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Antimicrobial photodynamic therapy with 5-aminolevulinic acid plus antibiotics: a promising treatment for tibial osteomyelitis caused by drug-resistant bacteria - Frontiers
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Possible Antiviral Activity of 5-Aminolevulinic Acid in Feline Infectious Peritonitis Virus (Feline Coronavirus) Infection - Frontiers
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5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Inhibits RIPK1/RIPK3-Dependent Necroptosis in THP-1-Derived Foam Cells - Nature
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Mechanistic studies on δ -aminolevulinic acid uptake and efflux in a mammary adenocarcinoma cell line - Nature
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Macroscopic fluorescence-lifetime imaging of NADH and protoporphyrin IX improves the detection and grading of 5-aminolevulinic acid-stained brain tumors | Scientific Reports - Nature
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Effect of photodynamic therapy with 5-aminolevulinic acid and EDTA-2Na against mixed infection of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa - Wiley Online Library
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5-Aminolevulinic Acid-Mediated Photodynamic Therapy Improves Vocal Fold Wound Healing in Rats - Wiley Online Library
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Neuroprotective effect of 5-aminolevulinic acid against low inorganic phosphate in neuroblastoma SH-SY5Y cells - Nature
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5-Aminolevulinic acid is a promising marker for detection of anaplastic foci in diffusely infiltrating gliomas with nonsignificant contrast enhancement - Wiley
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Reduction of oocyte shedding and cecal inflammation by 5-aminolevulinic acid daily supplementation in laying hens infected with Eimeria tenella - Wiley Online Library
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Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death - Wiley Online Library
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eEF1A1 binds and enriches protoporphyrin IX in cancer cells in 5-aminolevulinic acid based photodynamic therapy - Nature
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Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy - Nature
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In silico drug repurposing for filarial infection predicts nilotinib and paritaprevir as potential inhibitors of the Wolbachia 5′-aminolevulinic acid synthase - Nature
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FDA To Permit Using 3 Tubes of Actinic Keratosis Drug Per Treatment - Dermatology Times
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ABCG2 transporter inhibitor restores the sensitivity of triple negative breast cancer cells to aminolevulinic acid-mediated photodynamic therapy - Nature
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In order for the light to shine so brightly, the darkness must be present—why do cancers fluoresce with 5-aminolaevulinic acid? - Nature
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Topical 5-aminolevulinic acid photodynamic therapy for recalcitrant facial flat wart in Chinese subjects - Wiley Online Library
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No‐Needle Jet Intradermal Aminolevulinic Acid Photodynamic Therapy for Recurrent Nodular Basal Cell Carcinoma of the Nose: A Case Report - Barolet - 2011 - Journal of Skin Cancer - Wiley Online Library
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Case report: Acne vulgaris treatment with 5-Aminolaevulinic acid photodynamic therapy and adalimumab: a novel approach - Frontiers
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Simplified and optimized multispectral imaging for 5-ALA-based fluorescence diagnosis of malignant lesions - Nature
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NX Development Corp. (NXDC) Launches FDA-Approved Gleolan™ - GlobeNewswire
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Foliar application of 5-aminolevulinic acid alleviated high temperature and drought stresses on wheat plants at seedling stage - SciELO Chile
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CCID - Dove Medical Press
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Comparison of 15% 5-aminolevulinic acid and 10% 5-aminolevulinic acid photodynamic therapy for the treatment of acne vulgaris: a split-face randomized pilot study - Termedia
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5-aminolevulinic acid that fights against mitochondrial disorders: Research | Health - Hindustan Times
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FDA Approves sNDA for Actinic Keratosis Drug Dosage Expansion - Dermatology Times
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5-aminolevulinic acid may aid in the treatment of mitochondrial disorders - ET HealthWorld
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Porphyrin synthesis from ALA derivatives for photodynamic therapy. In vitro and in vivo studies - Nature
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Could a Naturally Occurring Amino Acid Lead Us to a Cure for COVID-19? - titech.ac.jp
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Delta-Aminolevulinic Acid-Based Photodynamic Therapy for Acne on The Body - ushio.co.jp
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δ-Aminolevulinic Acid Dehydratase Activity in Circulating Blood Cells | NEJM - NEJM
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.