Why is "Aminopterin" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-31 14:17:25
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
Aminopterin, the 4–amino derivative of folic acid, is an antineoplastic drug with immunosuppressive properties often used in chemotherapy. Aminopterin is a synthetic derivative of pterin. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrofolate reductase effectively blocks tetrahydrofolate synthesis. This results in the depletion of nucleotide precursors and inhibition of DNA, RNA, and protein synthesis.
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Trending Topic Today
Search Interest Perspective
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Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin) - nejm.org
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Veterinary researchers seek to confirm presence of toxins in recalled pet food and to explain cause of animals' kidney failure - Cornell Chronicle
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Optimizing our Success - Harvard Medical School
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Further case of aminopterin syndrome sine aminopterin in a Spanish child - Wiley Online Library
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Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin) - nejm.org
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We made great strides with childhood leukaemia – we can do the same for brain cancer - The Conversation
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Drug Therapeutics & Regulation in the U.S. - fda.gov
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Rat Poison Found in Pet Food Linked to 14 Deaths - Gainesville Sun
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Rat poison found in recalled pet food blamed for deaths of 16 dogs and cats - SouthCoastToday.com
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Monoclonal antibody discovery: current status and future perspectives - Drug Target Review
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Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest - nature.com
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Sixty Years Ago, a Rash of Mysterious Birth Defects Spurred a Doctor’s Search for Answers - National Endowment for the Humanities (.gov)
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Sidney Farber, Chemo Crusader - WNYC
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Rat poison found in tainted pet food - Times Herald-Record
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Pet Food Contained Chemical Found in Plastic, F.D.A. Says (Published 2007) - The New York Times
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Rat Poison Found in Recalled Pet Food - abcnews.com
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The road to cancer treatment through clinical trials - Worcester Telegram
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Recall Now Includes Dry Pet Food - CBS News
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A view on drug resistance in cancer - nature.com
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Worried local animal owners turning to homemade pet food - Times Herald-Record
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Pet Food Maker to Take Financial Responsibility for Pet Deaths From Poisoning - abcnews.com
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Chemotherapy tale has an Indian twist - India Today
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Rat poison found in tainted pet food - Ocala StarBanner
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Immunity booster - newindianexpress.com
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Rat Poison Found In Tainted Pet Food - CBS News
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Chemical Found in Recalled Pet Food - abcnews.com
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Unmasking the toxic culprit(s) in pet-food recalls - DVM360
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Biography of malignancy - Down To Earth
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The unsung Indian scientist who helped create chemotherapy and redefined cancer care - India Today
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Remembering the forgotten Indian biochemist who made pioneering contributions to cancer treatment - Scroll.in
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.