Why is "Anal canal" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-11 16:15:59
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
The anal canal is the part that connects the rectum to the anus, located below the level of the pelvic diaphragm. It is located within the anal triangle of the perineum, between the right and left ischioanal fossae. As the final functional segment of the bowel, it functions to regulate release of feces by two muscular anal sphincter complexes. The anus is the aperture at the terminal portion of the anal canal.
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Trending Topic Today
Search Interest Perspective
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Evaluating Retifanlimab for Advanced Squamous Cell Carcinoma of the Anal Canal in the Frontline Setting - HMP Global Learning Network
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European Commission OKs Retifanlimab Combo in Metastatic Anal Canal Cancer - CancerNetwork
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From the anal canal to the pancreas: diagnostic challenges of radiologic surveillance in detecting rare but potentially curable metastases — a case report - Frontiers
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Frontline Retifanlimab Approaches EU Approval for Advanced Squamous Cell Carcinoma of the Anal Canal - OncLive
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Methicillin-Resistant Staphylococcus aureus Septic Pulmonary Embolism Presumed to Originate From Anal Canal Cancer With a Cutaneous Fistula: A Case Report - Cureus
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NCCN: Squamous Cell Carcinoma of The Anal Canal Guidelines - Physician's Weekly
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Addition of Retifanlimab to First-Line Chemotherapy in Advanced Squamous Cell Carcinoma of the Anal Canal - The ASCO Post
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Incyte Announces the European Commission Approval of Zynyz® (retifanlimab) for the First-Line Treatment of Advanced Squamous Cell Carcinoma of the Anal Canal (SCAC) - BioSpace
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Chemoradiotherapy for anal canal cancers: Does the choice of boost technique matter? - Termedia
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She Had a Second Anus. Here's How Her Parents Found Out. - MedPage Today
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From Disease Staging to Treatment Strategy: Multidisciplinary Approaches in Newly Diagnosed Anal Canal Carcinoma - Targeted Oncology
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Incyte Drug Zynyz Approved in Europe for Anal Canal Cancer Treatment - MyChesCo
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FDA Approves Retifanlimab-dlwr with Chemotherapy and as Monotherapy for Advanced Squamous Cell Carcinoma of the Anal Canal - Oncodaily
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NCCN: Squamous Cell Carcinoma of The Anal Canal Guidelines - Physician's Weekly
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Incyte Announces Positive CHMP Opinion for Zynyz® (retifanlimab) for First-Line Treatment of Advanced Squamous Cell Carcinoma of the Anal Canal (SCAC) - BioSpace
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Epstein-Barr Virus-Positive Plasmablastic Lymphoma Arising in the Anal Canal of an Immunocompetent Patient - Cureus
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Addition of immunotherapy to chemotherapy improves progression-free survival in anal canal - ESMO Daily Reporter
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Retifanlimab Improves Survival in Squamous Cell Carcinoma of the Anal Canal - Physician's Weekly
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Cavernous Hemangioma of the Anal Canal Mimicking a Neoplasm: A Rare Cause of Lower Gastrointestinal Bleeding Successfully Treated With Transanal Excision - Cureus
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Incyte’s PD-1 Blocker Wins First-Line Anal Cancer Approval - BioSpace
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Early Diagnosis of Anal Canal Duplication: The Importance of a Physical Examination - Cureus
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Case Report: Anal canal duplication associated with anorectal stenosis—A rare presentation - Frontiers
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[18F]-FDG PET/CT in the Initial Staging of Squamous Cell Cancer of the Anal Canal: Results of a Prospective Multicenter Registry - Journal of Nuclear Medicine
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Anal Canal Duplication Mimicking Recurrent Abscess: A Case Report and Review of the Literature - Frontiers
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MRI anatomy and pathology of the anal canal - Erlichman - 2019 - Journal of Magnetic Resonance Imaging - Wiley Online Library
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Anal Canal Duplication in a 25-Year-Old Female Patient - Cureus
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A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalised medicine - Nature
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A Bleeding Dieulafoy's Lesion in the Anal Canal - Cureus
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Brazilian Society of Surgical Oncology: Guidelines for the management of anal canal cancer - Wiley Online Library
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HPV, p16 Associated With Outcomes in Anal Canal Carcinoma - CancerNetwork
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A Rare Case of HIV-Associated Plasmablastic Lymphoma of Anal Canal - Cureus
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Cancer of the anal canal - The Lancet
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Robot-assisted laparoscopic abdominoperineal resection for anal canal cancer associated with Crohn's disease: A case report - Wiley Online Library
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SIMS successfully performs surgery for rare cancer - The Hans India
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Case report: a precancerous lesion associated with HPV in the anal canal diagnosed by magnifying endoscopy with narrow-band imaging and resected by endoscopic submucosal dissection - Frontiers
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Cancers of the anal canal: diagnosis, treatment and future strategies - Oncology Central
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Human Papillomavirus-Associated Lymphoepithelioma-Like Carcinoma of the Anal Canal: A Case Report and Literature Review - Frontiers
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Rare Anal Canal Cancer with Secondary Extramammary Paget’s Disease (Pagetoid Spread) Complicated by Squamous Cell Carcinoma of the Skin - Wiley Online Library
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HPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53 | British Journal of Cancer - Nature
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ASTRO Issues Clinical Guideline on Radiation Therapy for Anal Cancer - The ASCO Post
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Complex Fistula-in-Ano Extending From the Anal Canal to Mid-Thigh Treated With Combine Fistulectomy and Video-Assisted Anal Fistula Treatment (VAAFT): A Case Report - Cureus
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Anal Canal Gas Gangrene in Aplastic Anaemia: Rare yet Lethal Entity - A Caveat - Cureus
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FDA Issues a Complete Response Letter for Retifanlimab for Squamous Cell Carcinoma of the Anal Canal - OncLive
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S1 nerve is the most efficient nerve rootlet innervating the anal canal and rectum in rats - Nature
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Colorectal Disease | ACPGBI Gastroenterology Journal - Wiley Online Library
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Condyloma acuminatum of the anal canal, treated with endoscopic submucosal dissection - Baishideng Publishing Group
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Human papillomavirus-related squamous cell carcinoma of the anal canal with papillary features - Baishideng Publishing Group
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VITAL phase 2 study: Upfront 5-fluorouracil, mitomycin-C, panitumumab and radiotherapy treatment in nonmetastatic squamous cell carcinomas of the anal canal (GEMCAD 09-02) - Wiley Online Library
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Extrapulmonary Small Cell Carcinoma of the Anal Canal: A Case Report and Review of the Literature - Wiley Online Library
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Case of Complete Remission After Volumetric Modulated Arc Therapy to Primary Tumor Alone in Locally Advanced Anal Canal Cancer With Active AIDS and Low CD4 Cell Count: Longest Survival in History? - Cureus
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Locality-dependent descending reflex motor activity in the anal canal–cholinergic and nitrergic contributions in the rat model - Nature
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Treatment algorithm and prognostic factors for patients with stage I–III carcinoma of the anal canal: a 20-year multicenter study - Nature
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Epidermoid Carcinoma of the Perianal Skin and Anal Canal — A Review of 157 Cases - NEJM
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Priming the Immune System in Anal Cancer: Does Immunotherapy Need a Helping Hand From Chemotherapy? - ASCO Daily News
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Metachronous Anal Canal and Prostate Cancers with Simultaneous Definitive Therapy: A Case Report and Review of the Literature - Wiley Online Library
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Metabolic Tumor Volume Predicts Disease Progression and Survival in Patients with Squamous Cell Carcinoma of the Anal Canal - Journal of Nuclear Medicine
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Plasmablastic plasmacytoma of the rectum and anal canal in a patient with ulcerative colitis - Termedia
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Pedunculated polypoid lymphangioma of the anal canal - Val‐Bernal - 2008 - Pathology International - Wiley Online Library
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Carcinoma of the Anal Canal - NEJM
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Anal adenocarcinoma: Treatment outcomes and trends in a rare disease entity - Wegner - 2019 - Cancer Medicine - Wiley Online Library
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Clinicopathological analysis of basal cell carcinoma of the anal region and its distinction from basaloid squamous cell carcinoma - Nature
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Expression of epidermal growth factor receptor in squamous cell carcinomas of the anal canal is independent of gene amplification - Nature
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Effective treatment of anal cancer in the elderly with low-dose chemoradiotherapy - Nature
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Haemorroidal prolapse into the anal canal - doccheck.com
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.