Why is "Anaphase Promoting Complex" trending?
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Trend Analysis
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- Date: 2026-04-06 05:01:44
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
Anaphase-promoting complex is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome. The APC/C is a large complex of 11–13 subunit proteins, including a cullin (Apc2) and RING (Apc11) subunit much like SCF. Other parts of the APC/C have unknown functions but are highly conserved.
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Trending Topic Today
Search Interest Perspective
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Lactate regulates cell cycle by remodelling the anaphase promoting complex - Nature
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Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer - PNAS
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Mass Spectrometric Analysis of the Anaphase-Promoting Complex from Yeast: Identification of a Subunit Related to Cullins - Science | AAAS
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The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma - Nature
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Different phosphorylation states of the anaphase promoting complex in response to antimitotic drugs: A quantitative proteomic analysis - PNAS
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Gene expression and cell identity controlled by anaphase-promoting complex - Nature
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Identification of a physiological E2 module for the human anaphase-promoting complex - PNAS
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Molecular architecture and mechanism of the anaphase-promoting complex - Nature
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SAMBA, a plant-specific anaphase-promoting complex/cyclosome regulator is involved in early development and A-type cyclin stabilization - PNAS
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Spatiotemporal regulation of the anaphase-promoting complex in mitosis - Nature
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Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes - PNAS
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Phosphorylation of the Anaphase Promoting Complex activator FZR1/CDH1 is required for Meiosis II entry in mouse male germ cell - Nature
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Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint - PNAS
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The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites - Nature
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Two different mitotic checkpoint inhibitors of the anaphase-promoting complex/cyclosome antagonize the action of the activator Cdc20 - PNAS
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Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription - Nature
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Cell cycle deregulation by a poxvirus partial mimic of anaphase-promoting complex subunit 11 - PNAS
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piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis - Nature
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Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C) - Nature
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Specificity of the anaphase-promoting complex: A single-molecule study - Science | AAAS
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The Role of Anaphase-Promoting Complex/Cyclosome (APC/C) in Plant Reproduction - Frontiers
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Roles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding - PNAS
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Bifidobacterium infantis Maintains Genome Stability in Ulcerative Colitis via Regulating Anaphase-Promoting Complex Subunit 7 - Frontiers
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Anaphase-promoting complex/cyclosome regulates RdDM activity by degrading DMS3 in Arabidopsis - PNAS
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Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex - Nature
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Control the Host Cell Cycle: Viral Regulation of the Anaphase-Promoting Complex - ASM Journals
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ATP is required for the release of the anaphase-promoting complex/cyclosome from inhibition by the mitotic checkpoint - PNAS
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The Anaphase Promoting Complex/Cyclosome Subunit 11 and Its Role in Organ Size and Plant Development - Frontiers
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UBE2S drives elongation of K11-linked ubiquitin chains by the Anaphase-Promoting Complex - PNAS
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Cdc20 directs proteasome-mediated degradation of the tumor suppressor SMAR1 in higher grades of cancer through the anaphase promoting complex - Nature
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Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth - Nature
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Author Correction: piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis - Nature
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The anaphase-promoting complex: a key factor in the regulation of cell cycle - Nature
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Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells - Nature
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Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation - Nature
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The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint - Nature
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The Doc1 subunit is a processivity factor for the anaphase-promoting complex - Nature
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Alterations of anaphase-promoting complex genes in human colon cancer cells - Nature
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Structure, function and mechanism of the anaphase promoting complex (APC/C) - Cambridge University Press & Assessment
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Identification of human APC10/Doc1 as a subunit of anaphase promoting complex - Nature
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complexes provide insights into APC/C regulation - Nature
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Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex - Nature
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Saccharomyces cerevisiae (Anaphase-promoting complex) - CIL:35653 - doccheck.com
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