Why is "Anaplastic large cell lymphoma" trending?
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- Date: 2026-04-03 01:33:08
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Wikipedia Overview
Anaplastic large-cell lymphoma (ALCL) refers to a group of non-Hodgkin lymphomas in which aberrant T cells proliferate uncontrollably. Considered as a single entity, ALCL is the most common type of peripheral lymphoma and represents ~10% of all peripheral lymphomas in children. The incidence of ALCL is estimated to be 0.25 cases per 100,000 people in the United States of America. There are four distinct types of anaplastic large-cell lymphomas that on microscopic examination share certain key histopathological features and tumor marker proteins. However, the four types have very different clinical presentations, gene abnormalities, prognoses, and/or treatments.
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Brentuximab vedotin plus chemotherapy for the treatment of front-line systemic anaplastic large cell lymphoma: subgroup analysis of the ECHELON-2 study at 5 years’ follow-up | Blood Cancer Journal - Nature
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Anaplastic Large Cell Lymphoma Related to Breast Implant Presenting as a Solid mass: A Case Report - onlinelibrary.wiley.com
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Case Report: diffuse entire gastrointestinal tract involvement of ALK-positive anaplastic large cell lymphoma harboring JAK-STAT pathway mutations in an adolescent with leukemoid reaction - Frontiers
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Complete Remission of Recurrent Primary Cutaneous Anaplastic Large Cell Lymphoma Following Bexarotene Therapy: A Case Report - Cureus
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Breast Implant–associated Anaplastic Large Cell Lymphoma | RadioGraphics - RSNA Journals
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Rare Primary ALK-Positive Anaplastic Large Cell Lymphoma of the Central Nervous System - CancerNetwork
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Anaplastic large-cell lymphoma mimicking cellulitis in an 8-year-old boy - CMAJ
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Anaplastic Large Cell Lymphoma (ALCL) and hernia mesh implants: an unrecognised association - medRxiv
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BRCA Mutations Up Risk of ALCL in Those with Textured Implants - Breast Cancer.org
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The IL-1R and NFKBIZ pathway mediates immunoregulatory responses and immunotherapy efficacy in anaplastic large cell lymphoma | Leukemia - Nature
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Primary Gingival Anaplastic Lymphoma Kinase (ALK)-Positive Anaplastic Large Cell Lymphoma in a Young Boy - Cureus
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Implant-based reconstruction linked to increased risk of breast lymphomas - medicalxpress.com
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Tackling anaplastic large cell lymphoma where it lives - answers.childrenshospital.org
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PTPN2 Inhibition Disrupts Mitochondrial Renewal and Blocks TFRC-Mediated Mitophagy to Exert Anti-Tumor Activities in ALK-Positive Anaplastic Large Cell Lymphoma - Wiley
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Anaplastic Lymphoma Kinase (ALK)-Positive Anaplastic Large Cell Lymphoma Presenting as an Axillary Breast Abscess in a Young Woman: A Case Report - Cureus
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Circulating tumor DNA in ALK-positive anaplastic large cell lymphoma: a proof-of-concept study - Nature
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Brentuximab vedotin use in pediatric anaplastic large cell lymphoma - Frontiers
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Successful Re-administration and Extended Dosing of Brentuximab Vedotin Monotherapy for Relapsed Anaplastic Large Cell Lymphoma in a Vulnerable Patient - Cureus
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Breast implant-associated anaplastic large cell lymphoma: a review - Nature
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Comprehensive genomic analysis reveals molecular heterogeneity in pediatric ALK-positive anaplastic large cell lymphoma | Leukemia - Nature
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PD-L1 expression in anaplastic large cell lymphoma - Nature
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DUSP22-rearranged ALK-negative anaplastic large cell lymphoma is a pathogenetically distinct disease but can have variable clinical outcome - Haematologica
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Updates in pathobiological aspects of anaplastic large cell lymphoma - Frontiers
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HDAC1 acts as a tumor suppressor in ALK-positive anaplastic large cell lymphoma: implications for HDAC inhibitor therapy | Leukemia - Nature
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Images from the Haematologica Atlas of Hematologic Cytology: anaplastic large cell lymphoma, ALK-negative - Haematologica
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ALK-positive anaplastic large cell lymphoma with prominent bone involvement in a 13-year-old boy - Oncology Nurse Advisor
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Anaplastic large cell lymphoma: changes in the World Health Organization classification and perspectives for targeted therapy - Haematologica
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ALK-negative anaplastic large cell lymphoma is sensitive to bortezomib through Noxa upregulation and release of Bax from Bcl-2 - Haematologica
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Profound and sustained response with next-generation ALK inhibitors in patients with relapsed or progressive ALK-positive anaplastic large cell lymphoma with central nervous system involvement - Haematologica
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Anaplastic large cell lymphoma masquerading as classical Hodgkin lymphoma on fine needle aspiration: A potential diagnostic pitfall - onlinelibrary.wiley.com
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Recurrent somatic mutations of FAT family cadherins induce an aggressive phenotype and poor prognosis in anaplastic large cell lymphoma | British Journal of Cancer - Nature
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Breast Implant-Associated Anaplastic Large Cell Lymphoma - Cleveland Clinic
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Treatment Guidelines for Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) - University of Colorado Anschutz
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Anaplastic Large-Cell Lymphoma (ALCL) First Manifested as a Rapidly Progressive Acute Respiratory Failure (RF): Lymph Node Biopsy Negative Presentation Posing a Diagnostic Challenge - Cureus
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ALK-Positive Anaplastic Large Cell Lymphoma Associated With Hemophagocytic Lymphohistiocytosis - Cureus
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Primary Cutaneous Anaplastic Large Cell Lymphoma of the Nasal Dorsum and Nasal Tip - Cureus
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Best Practices for Diagnosing Breast Implant-Associated Anaplastic Large Cell Lymphoma - Cancer Therapy Advisor
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Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress - Nature
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Inhibition of MCL1 induces apoptosis in anaplastic large cell lymphoma and in primary effusion lymphoma - Nature
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Primary Anaplastic Lymphoma Kinase (ALK)-Negative Anaplastic Large Cell Lymphoma (ALCL) Presenting as Perforation Peritonitis: A Case Report and Management Principles - Cureus
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Recurrent Primary Cutaneous Anaplastic Large Cell Lymphoma With Systemic Involvement: A Case Report and Literature Review - Cureus
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Primary Cutaneous Anaplastic Large Cell Lymphoma With Gastric Metastasis - Cureus
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Anaplastic large-cell lymphoma: Combination therapy recommended to prevent treatment resistance - medicalxpress.com
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Allergan Breast Implant Lawsuit Lawyers - July 2025 Update - levinlaw.com
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Super-enhancer-based identification of a BATF3/IL-2R−module reveals vulnerabilities in anaplastic large cell lymphoma - Nature
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New Study From Fox Chase Cancer Center Researchers Identifies Key Immunological Pathway in ALCL Lymphoma - Fox Chase Cancer Center
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Breast Implant-associated Anaplastic Large Cell Lymphoma Affecting a Neosubpectoral Pocket - Cureus
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Diagnostic and therapeutic challenges of ALK-positive anaplastic large cell lymphoma: case report and literature review - journals.viamedica.pl
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Breast Implant–Associated Anaplastic Large Cell Lymphoma - Wiley
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The long non-coding RNA LINC01013 enhances invasion of human anaplastic large-cell lymphoma - Nature
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Breast implant-associated anaplastic large cell lymphoma: clinical follow-up and analysis of sequential pathologic specimens of untreated patients shows persistent or progressive disease - Nature
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Unusual Late Relapse of ALK-Positive Anaplastic Large Cell Lymphoma Successfully Cleared Using the ALK-Inhibitor Crizotinib: Case Report - Frontiers
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Management of a Patient with Systemic Anaplastic Large Cell Lymphoma following Failure of One or More Combination Regimens - The ASCO Post
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A Rare and Isolated Presentation of Primary Cutaneous Anaplastic Large Cell Lymphoma on the Breast - Cureus
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Characteristics and Outcomes of Chinese Children With Advanced Stage Anaplastic Large Cell Lymphoma: A Single-Center Experience - Frontiers
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Anaplastic Large Cell Lymphoma Growing in the Pacemaker Pocket: - JACC Journals
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What Physicians Should Know About Breast Implant-Associated Anaplastic Large Cell Lymphoma - CancerNetwork
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Pediatric Anaplastic Large Cell Lymphoma Presenting as Generalized Lymphadenopathy - CancerNetwork
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Crizotinib in Anaplastic Large-Cell Lymphoma - NEJM
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Central nervous system relapse in a child with anaplastic large cell lymphoma: potential for new therapeutic strategies - onlinelibrary.wiley.com
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Reduced‐Intensity Conditioning May Improve Survival in Relapsed/Refractory Anaplastic Large Cell Lymphoma - Hematology Advisor
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A novel immunohistochemical classifier to distinguish Hodgkin lymphoma from ALK anaplastic large cell lymphoma - Nature
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Insights into the Microbiome of Breast Implants and Periprosthetic Tissue in Breast Implant-Associated Anaplastic Large Cell Lymphoma - Nature
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JAK2 activation promotes tumorigenesis in ALK-negative anaplastic large cell lymphoma via regulating oncogenic STAT1-PVT1 lncRNA axis - Nature
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Diagnostic and therapeutic challenges of ALK-positive anaplastic large cell lymphoma: case report and literature review - journals.viamedica.pl
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Incidental discovery of invasive lobular carcinoma and anaplastic large cell lymphoma during sentinel lymph node biopsy: a case report - Frontiers
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Breast Implant‐Associated Anaplastic Large Cell Lymphoma - Moori - 2020 - Case Reports in Pathology - onlinelibrary.wiley.com
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Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma - Leukemia - Nature
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Targetable fusions of the FRK tyrosine kinase in ALK-negative anaplastic large cell lymphoma - Nature
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Partial Response to Small Molecule Inhibition in a Case of Anaplastic Large Cell Lymphoma - Cureus
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Breast Implant-Associated Anaplastic Large Cell Lymphoma: Symptoms, Diagnosis and Treatment - Cure Today
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Novel ALK fusion in anaplastic large cell lymphoma involving EEF1G, a subunit of the eukaryotic elongation factor-1 complex - Nature
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Dermatology Review/Przegląd Dermatologiczny - Termedia
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Effusion-associated anaplastic large cell lymphoma of the breast: time for it to be defined as a distinct clinico-pathological entity - Haematologica
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Breast Implant-Associated Anaplastic Large Cell Lymphoma Presenting in a Postpartum Patient: A Case Report - Cureus
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Use of flow cytometry and cytology to differentiate breast implant-associated anaplastic large cell lymphoma from reactive seromas in Brazilian patients - onlinelibrary.wiley.com
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Breast Implant-Associated Anaplastic Large Cell Lymphoma: A Case Report and Literature Review - Cureus
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Cutaneous presentation of ALK-positive anaplastic large cell lymphoma following insect bites: evidence for an association in five cases - Haematologica
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Analysis and therapeutic targeting of the EP300 and CREBBP acetyltransferases in anaplastic large cell lymphoma and Hodgkin lymphoma - Nature
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Breast Implant Cancer: Risk Factors, Symptoms, and Treatment - Healthline
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Primary Cutaneous CD30+ Anaplastic Large Cell Lymphoma: A Rare Association With Large Plaque Parapsoriasis - Cureus
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Breast Implants Linked to Anaplastic Large-Cell Lymphoma - CancerNetwork
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Role of flow cytometric immunophenotyping in the diagnosis of breast implant-associated anaplastic large cell lymphoma: A 6-year, single-institution experience - onlinelibrary.wiley.com
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FDA approves Adcetris® (brentuximab vedotin) for treatment of primary cutaneous anaplastic large cell lymphoma - Lymphoma Hub
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Seroma-associated primary anaplastic large-cell lymphoma adjacent to breast implants: an indolent T-cell lymphoproliferative disorder - Nature
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Characteristics and clinical outcomes of patients with ALK-positive anaplastic large cell lymphoma: Report from the prospective international T-cell lymphoma project - onlinelibrary.wiley.com
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Cytomorphologic examination of anaplastic large cell lymphoma by fine-needle aspiration cytology - Wiley
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Mum 'almost killed by boob job' after doctors discovered rare type of cancer linked to her scandal-hit brand of implant - LADbible
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RIP1 expression is necessary for CD30-mediated cell death induction in anaplastic large-cell lymphoma cells - Nature
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Hitting a Home Run with an Investigational Drug - National Cancer Institute (.gov)
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Prevalence and clinical implications of bone marrow involvement in pediatric anaplastic large cell lymphoma - Nature
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Anaplastic Large Cell Lymphoma Misdiagnosed as Systemic Lupus Erythematosus: A Report of a Rare Case - Cureus
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Primary Anaplastic Large Cell Lymphoma of the Lung: A Clinicopathologic Study of Five Patients - Nature
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Specificity of IRF4 translocations for primary cutaneous anaplastic large cell lymphoma: a multicenter study of 204 skin biopsies | Modern Pathology - Nature
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Caspase-3 activation in systemic anaplastic large-cell lymphoma - Nature
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FDA Approves Brentuximab Vedotin for Hodgkin Lymphoma and Systemic Anaplastic Large-Cell Lymphoma - CancerNetwork
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Evaluation of treatment results in multifocal primary cutaneous anaplastic large cell lymphoma: report of the Dutch Cutaneous Lymphoma Group - onlinelibrary.wiley.com
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Brentuximab vedotin in Relapsed Anaplastic Large Cell Lymphoma - Lymphoma Hub
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Trusting in a Clinical Trial for Anaplastic Large Cell Lymphoma - aacr.org
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Peripheral T-Cell Lymphoma Treatment & Pharmacologic Management - Cancer Therapy Advisor
Why This Topic Is Trending
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