Why is "Aneuploidy" trending?

Search Interest Perspective

• Chromosome Segregation Defects Contribute to Aneuploidy in Normal Neural Progenitor Cells - Journal of Neuroscience
• Common variation in meiosis genes shapes human recombination and aneuploidy - Nature
• Genetic Basis of Aneuploidy, Which Often Causes Pregnancy Loss, Revealed - the-scientist.com
• Acta Obstetricia et Gynecologica Scandinavica | NFOG Women's Health Journal | Wiley Online Library - Wiley
• Genetic Variants Linked to Pregnancy Loss Uncovered - Inside Precision Medicine
• New Study Uncovers How Cancer Cells Tolerate Missing Chromosomes - Yale School of Medicine
• Study reveals implantation and live birth rates for segmental aneuploid embryos - Contemporary OB/GYN
• Common genetic variants affect risk of a major cause of pregnancy loss - Nature
• In a first, study links maternal genes to risk of pregnancy loss - Live Science
• Roots of Many Miscarriages May Trace Back To Before The Mother Is Even Born - ScienceAlert
• A large study finds genetic variants associated with pregnancy loss - Science Media Centre España
• First Healthy Twins Born After Aneuploid Embryo Transfer - European Medical Journal
• WES-Aneuploidy Scores May Be Prognostic for Immunotherapy in dMMR Endometrial Cancer - OncLive
• Hidden in Plain Sight: A Rare 7q Deletion Masquerading as a Common Aneuploidy on Prenatal Ultrasound - Cureus
• 1q gain bypasses the selective barrier against aneuploidy in RPE differentiation via wild-type co-culture rescue - Nature
• Combined Preimplantation Genetic Testing for Aneuploidy (PGT-A) and Monogenic Disorders (PGT-M) to Prevent Autosomal Dominant Polycystic Kidney Disease After Kidney Transplant - Cureus
• A new tool for understanding chromosome abnormalities in the eggs of older women - YaleNews
• Inducible chromosomal rearrangement reveals nonlinear polygenic dosage effects in driving aneuploid yeast traits - Nature
• A versatile cohesion manipulation system probes female reproductive age-related egg aneuploidy - Nature
• Aneuploidy-driven vulnerabilities in breast cancer metastasis - Nature
• Healthy twins born from uniformly aneuploid embryos - Progress Educational Trust
• Aneuploidy-induced proteostasis disruption impairs mitochondrial functions and mediates aggregation of mitochondrial precursor proteins through SQSTM1/p62 - Nature
• Tumor aneuploidy as a prognostic and predictive biomarker in immune checkpoint blockade - Nature
• Conventional in vitro fertilization enhances preimplantation genetic testing for aneuploidy outcomes in couples with non-male factor infertility - Nature
• Detection of chromosomal aneuploidy in ancient genomes - Communications Biology - Nature
• Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns - Nature
• Oncogene-like addiction to aneuploidy in human cancers - Science | AAAS
• Natural proteome diversity links aneuploidy tolerance to protein turnover - Nature
• On the origin of mitosis-derived human embryo aneuploidy - Nature
• Aneuploidy confers a unique transcriptional and phenotypic profile to Candida albicans - Nature
• Aneuploidy as a driver of human cancer - Nature
• Aneuploidy May Help Tumors Become Resistant to Treatment - National Cancer Institute (.gov)
• Acquisition of aneuploidy drives mutant p53-associated gain-of-function phenotypes - Nature
• Aging-related aneuploidy is associated with mitochondrial imbalance and failure of spindle assembly - Nature
• Aneuploidy in mammalian oocytes and the impact of maternal ageing - Nature
• Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood - PNAS
• Human MLH1/3 variants causing aneuploidy, pregnancy loss, and premature reproductive aging - Nature
• Chromosomal abnormality scores unlock path to personalized immunotherapy - UChicago Medicine
• Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition - Nature
• Clinical and molecular correlates of tumor aneuploidy in metastatic non-small cell lung cancer - Nature
• Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage - Nature
• Maternal genetic variants in kinesin motor domains prematurely increase egg aneuploidy - PNAS
• Live Birth with or without Preimplantation Genetic Testing for Aneuploidy - NEJM
• Normal breast tissues harbour rare populations of aneuploid epithelial cells - Nature
• Aneuploidy and complex genomic rearrangements in cancer evolution - Nature
• Developmental potential of aneuploid human embryos cultured beyond implantation - Nature
• Maternal ELL3 loss-of-function leads to oocyte aneuploidy and early miscarriage - Nature
• Exploiting tumor aneuploidy as a biomarker and therapeutic target in patients treated with immune checkpoint blockade - Nature
• Whole genome analysis reveals aneuploidies in early pregnancy loss in the horse | Scientific Reports - Nature
• New tool to generate aneuploidies and analyse their impact on development - Institute for Research in Biomedicine | IRB Barcelona
• Frequent aneuploidy in primary human T cells after CRISPR–Cas9 cleavage - Nature
• Effects of aneuploidy on cell behaviour and function - Nature
• Molecular signatures of aneuploidy-driven adaptive evolution - Nature
• Research Tool Generates Aneuploid Cells to Study Fertility and Cancer - Genetic Engineering and Biotechnology News
• Aneuploidy causes premature differentiation of neural and intestinal stem cells - Nature
• Aneuploidy tolerance caused by BRG1 loss allows chromosome gains and recovery of fitness - Nature
• Cancer aneuploidies are shaped primarily by effects on tumour fitness - Nature
• Human embryos harbor complex mosaicism with broad presence of aneuploid cells during early development - Nature
• Aneuploidy in the driving seat - Nature
• DNA Sequencing versus Standard Prenatal Aneuploidy Screening - NEJM
• Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy - Science | AAAS
• An original aneuploidy-related gene model for predicting lung adenocarcinoma survival and guiding therapy - Nature
• Inadequate histone deacetylation during oocyte meiosis causes aneuploidy and embryo death in mice - PNAS
• Davis Is First Author on Sex Chromosome Aneuploidy Original Investigation - University of Colorado Anschutz
• Hypo-osmotic-like stress underlies general cellular defects of aneuploidy - Nature
• Aneuploid embryonic stem cells drive teratoma metastasis - Nature
• Targeting aneuploidy to treat cancer - Drug Discovery News
• Origins and mechanisms leading to aneuploidy in human eggs - Wartosch - 2021 - Prenatal Diagnosis - Wiley
• Rapid Nanopore Sequencing–Based Screen for Aneuploidy in Reproductive Care - NEJM
• Tumor aneuploidy predicts survival following immunotherapy across multiple cancers - Nature
• Aneuploidy as a promoter and suppressor of malignant growth - Nature
• Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders - Frontiers
• CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy - PNAS
• Aneuploidy enables adaptation to brefeldin A in Candida albicans - Frontiers
• Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 - Nature
• Aneuploidy drives lethal progression in prostate cancer - PNAS
• Single cell sequencing reveals low levels of aneuploidy across mammalian tissues - PNAS
• Short- and long-term effects of chromosome mis-segregation and aneuploidy - Nature
• Proteome imbalance from aneuploidy linked to mitochondrial dysfunction - News-Medical
• Minimally Invasive Cell-Free Human Embryo Aneuploidy Testing (miPGT-A) Utilizing Combined Spent Embryo Culture Medium and Blastocoel Fluid –Towards Development of a Clinical Assay - Nature
• Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of BRCA2 mutation carriers - Science | AAAS
• Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism - Nature
• Chromosome instability and aneuploidy as context-dependent activators or inhibitors of antitumor immunity - Frontiers
• High concordance in preimplantation genetic testing for aneuploidy between automatic identification via Ion S5 and manual identification via Miseq - Nature
• Successful live birth of a healthy infant by preimplantation genetic testing for aneuploidy in a couple with recurrent spontaneous abortion: a case report - Frontiers
• Oocyte aneuploidy rates in river and swamp buffalo types ( Bubalus bubalis ) determined by Multi-color Fluorescence In Situ Hybridization (M-FISH) - Nature
• The ATM–p53 pathway suppresses aneuploidy-induced tumorigenesis - PNAS
• A single-cell transcriptome atlas of human euploid and aneuploid blastocysts - Nature
• Digital PCR for the molecular detection of fetal chromosomal aneuploidy - PNAS
• FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence - Nature
• Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility - Science | AAAS
• Global modulation of gene expression and transcriptome size in aneuploid combinations of maize - PNAS
• Dual adaptive strategies in Candida glabrata under tunicamycin stress: petite mutations and chromosome C aneuploidy drive transient drug resistance - Frontiers
• Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis - Nature
• Age‐associated aneuploidy: Loss of Y chromosome from human bone marrow cells with aging - Wiley
• Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms - PNAS
• Contribution of histone variants to aneuploidy: a cancer perspective - Frontiers
• Chromosomal phase improves aneuploidy detection in non-invasive prenatal testing at low fetal DNA fractions - Nature
• Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion - Nature
• Artificially decreasing cortical tension generates aneuploidy in mouse oocytes - Nature