Why is "Anophthalmia" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-29 02:21:40
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
Anophthalmia is the medical term for the absence of one or both eyes. Both the globe and the ocular tissue are missing from the orbit. The absence of the eye will cause a small bony orbit, a constricted mucosal socket, short eyelids, reduced palpebral fissure and malar prominence. Genetic mutations, chromosomal abnormalities, and prenatal environment can all cause anophthalmia. Anophthalmia is an extremely rare disease and is mostly rooted in genetic abnormalities. It can also be associated with other syndromes.
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Search Interest Perspective
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Genotypic and phenotypic spectrum of anophthalmia/microphthalmia in families from Khyber Pakhtunkhwa, Pakistan - Nature
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Born Without Eyes and Ultrasound Couldn't See - ABC News
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Congenital bilateral clinical anophthalmia and brachygnathia superior in a fighting bull calf - Wiley Online Library
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Screening of SOX2 in Patients With Anophthalmia/Microphthalmia: Identification of New Mutations - ARVO Journals
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Clinical and genetic analysis further delineates the phenotypic spectrum of ALDH1A3-related anophthalmia and microphthalmia | European Journal of Human Genetics - Nature
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Bilateral anophthalmia: Baby born without eyes due to extremely rare condition - The Independent
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Prenatal Ultrasound Diagnosis of Congenital Diaphragmatic Hernia in a Fetus With Fryns “Anophthalmia-Plus” Syndrome: A Case Report - Cureus
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Non-syndromic anophthalmia/microphthalmia can be caused by a PORCN variant inherited in X-linked recessive manner - Wiley Online Library
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Children and young adults with anophthalmia/microphthalmia treated with ocular prosthesis - ARVO Journals
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Molecular investigation in individuals with orofacial clefts and microphthalmia-anophthalmia-coloboma spectrum - Nature
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SOX2 anophthalmia syndrome and dental anomalies - Wiley Online Library
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Orbital Volume Augmentation Using Expandable Hydrogel Implants in Acquired Anophthalmia and Phthisis Bulbi - ARVO Journals
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Novel mutations in PAX6, OTX2 and NDP in anophthalmia, microphthalmia and coloboma - Nature
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Antenatal diagnosis of anophthalmia by three-dimensional ultrasound: a novel application of the reverse face view - Wiley
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Identification of novel pathogenic variants and novel gene-phenotype correlations in Mexican subjects with microphthalmia and/or anophthalmia by next-generation sequencing - Nature
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EP03.11: Prenatal ultrasound analysis of 33 cases of fetal anophthalmia and microphthalmia - Wiley
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Isolated hypogonadotropic hypogonadism with SOX2 mutation and anophthalmia/microphthalmia in offspring - Nature
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Prenatal diagnosis of bilateral anophthalmia: Identifying de novo SOX2 variant - Wiley
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Anopthalmia/microphthlamia-esophageal atresia association with additional features imperforate anus, choanal atresia, cyanotic heart disease - Nature
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Mutations in SOX2 cause anophthalmia - Nature
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Mutation spectrum and phenotypic variation in nine patients with SOX2 abnormalities - Nature
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Correction: Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice - PLOS
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Delineation of an estimated 6.7 MB candidate interval for an anophthalmia gene at 3q26.33-q28 and description of the syndrome associated with visible chromosome deletions of this region - Nature
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Twin baby girl born with incredibly rare condition that means she has no eyes - LADbible
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Novel SOX2 partner-factor domain mutation in a four-generation family | European Journal of Human Genetics - Nature
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Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia - Wiley Online Library
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California twins suffering from rare disorder were born without eyes - WQAD
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A newborn with anophthalmia and pulmonary hypoplasia (the Matthew–Wood syndrome) - Wiley Online Library
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Student who is blind pursues her dreams with the help of her teachers - ABC News
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After giving birth to a daughter with no eyes, family finds strength, hope through support groups - MLive.com
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SOX2 anophthalmia syndrome - Ragge - 2005 - American Journal of Medical Genetics Part A - Wiley Online Library
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Trisomy 2 mosaicism with caudal dysgenesis, Hirschsprung disease, and micro-anophthalmia - Wiley Online Library
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Anophthalmia-esophageal atresia syndrome caused by an SOX2 gene deletion in monozygotic twin brothers with markedly discordant phenotypes - Wiley Online Library
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The PDAC syndrome (pulmonary hypoplasia/agenesis, diaphragmatic hernia/eventration, anophthalmia/microphthalmia, and cardiac defect) (Spear syndrome, Matthew-Wood syndrome): Report of eight cases including a living child and further evidence for au - Wiley Online Library
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Demographics and histopathological characteristics of enucleated microphthalmic globes - Nature
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Baby girl born without eyes stuns parents - News.com.au
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Unilateral Anophthalmic Socket Reconstruction With Dermis Fat Graft - Cureus
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Eye Conformers as Socket Expanders in Children: Experience at a Tertiary Eye Hospital in Central Saudi Arabia - Cureus
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Acta Obstetricia et Gynecologica Scandinavica | NFOG Women's Health Journal | Wiley Online Library - Wiley
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Parents of Taunton boy born without eyes heading to Orlando conference - Taunton Daily Gazette
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Anophthalmia Leaves Newborn With No Eyes, But Transplant Advancements May Make Seeing Possible - Medical Daily
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Twins with rare genetic disorder born without eyes - KVUE
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Molecular links among the causative genes for ocular malformation: Otx2 and Sox2 coregulate Rax expression - PNAS
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Homozygous null mutation in ODZ3 causes microphthalmia in humans - Nature
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Boy born without eyes is 'such a good baby,' his mom says - WHAS11
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Peoria family calls baby born without eyes ‘a blessing’ - Rockford Register Star
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Baby Boy From New Mexico Is Born Without Eyes: 'It Was Complete Shock' - People.com
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Shocking! Baby Born Without Eyes Due to An Extremely Rare Genetic Disorder - Times Now
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Nurses trying to find abandoned baby without eyes new home - New York Post
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Unraveling the genetic cause of a consanguineous family with unilateral coloboma and retinoschisis: expanding the phenotypic variability of RAX mutations - Nature
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Baby Born Without Eyes Due to Rare Disorder - Fox News
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3D-Printed 'Eyes' Could Help Blind Children's Faces Grow Naturally - Live Science
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My baby was born without eyes and had half her brain removed — but she’s thriving - New York Post
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Video: Florida baby born without eyes - SILive.com
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Girl born with no eyes ‘has changed our lives for the better’, say parents - Indy100
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Baby boy born with no eyes: Rare condition Anophthalmia means child will never see - Daily Express
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Girl born with no eyes ‘has changed our lives for the better’, say parents - London Evening Standard
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Our beautiful baby girl was born with no eyes but it was hours before we realised something was wrong - The Sun
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Peoria family calls baby born without eyes ‘a blessing’ - Peoria Journal Star
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York: Girl born without eyes 'beautiful inside and out' - BBC
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Stockton twins with rare genetic disorder born without eyes - ABC10
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Baby born without eyes is example of the limits of ultrasounds: report - New York Daily News
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Girl born with no eyes ‘has changed our lives for the better’, say parents - Bracknell News
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Born Without Eyes - NBC Connecticut
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Pictured: Baby born with NO EYES after developing rare condition in his mother's womb - The Mirror
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Arizona Baby Born Without Eyeballs - wfmynews2.com
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Orphan baby born with no eyes has loving new home for Christmas - The Mirror
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MYSTERY OF BABIES WITHOUT EYES - Orlando Sentinel
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Parents stunned as baby girl born without EYES due to rare genetic disorder which only affects 30 people in world - The Sun
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Mum whose twin daughter was born without eyes says child is ‘thriving’ despite extremely rare condition - Ireland Live
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My son was born without eyes and I was told he would die before he was even born - but then a miracle happened - the-sun.com
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Boy Born Without Eyes Is 'Such a Good Baby,' His Mom Says - Inside Edition
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Baby born without eyes needs new home after mum abandoned him - Metro.co.uk
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Our beautiful little girl was born without eyes - Manchester Evening News
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Baby born with no eyes in Guangzhou, China - Metro.co.uk
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Health | Pesticide link to eye abnormalities - BBC
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Missouri School Swaps Blind Child's Cane With Pool Noodle As Punishment - Medical Daily
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Mum abandons baby born without eyes - News.com.au
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Twins born without eyes - Emirates 24|7
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'Miracle' baby Archie born without eyes one of just two cases ever diagnosed - SMH.com.au
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Goat born with no eyes and human like lips branded evil - The Asian Age
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Baby born with no eyes - Emirates 24|7
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Family’s despair over baby born without eyes - The Namibian -
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Young Mother Struggles to Care for Son Born Without Eyes - Nilepost News
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‘Our daughter was born with no eyes - our world shattered, but our lives changed for the better’ - OK! Magazine
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The Baby Boy With No EYES - Daily Trust
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Sydney baby born without eyes - Post Courier
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Cwmbran family of baby born without eyes 'overwhelmed' by support - South Wales Argus
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The Tragic Story of Le Van O: Born Without Eyes Due to Agent Orange - hypefresh.com
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Baby will never see his mother's face after being born without eyes due to anophthalmia - Daily Mail
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Baby, 1, born without eyes undergoes 'socket stretching' so he can have prosthetics implanted - Daily Mail
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Couple recounts when they realized their son was born without eyes - Daily Mail
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Chinese mother is devastated after her son was born with no eyes - Daily Mail
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The baby girl born with no EYES: Rare condition means child will never see - Daily Mail
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.