Why is "Antitoxins" trending?
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Trend Analysis
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- Date: 2026-03-30 03:55:19
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Wikipedia Overview
An antitoxin is an antibody with the ability to neutralize a specific toxin. Antitoxins are produced by certain animals, plants, and bacteria in response to toxin exposure. Although they are most effective in neutralizing toxins, they can also kill bacteria and other microorganisms. Antitoxins are made within organisms, and can be injected into other organisms, including humans, to treat an infectious disease. This procedure involves injecting an animal with a safe amount of a particular toxin. The animal's body then makes the antitoxin needed to neutralize the toxin. Later, blood is withdrawn from the animal. When the antitoxin is obtained from the blood, it is purified and injected into a human or other animal, inducing temporary passive immunity. To prevent serum sickness, it is often best to use an antitoxin obtained from the same species.
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Trending Topic Today
Search Interest Perspective
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Bistability in type I toxin-antitoxin systems may lead to stress-induced persister formation - Nature
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Beyond plasmid addiction: the role of toxin–antitoxin systems in the selfish behavior of mobile genetic elements - ASM Journals
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Antibody-based alternatives to animal testing for toxin detection and antitoxin evaluation - Frontiers
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Surface expression of antitoxin on engineered bacteria neutralizes genotoxic colibactin in the gut - Nature
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Diphtheria: A hundred years ago, the first toxoid vaccine | - Institut Pasteur
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Bacteria-fighting antitoxins offer remedy to antibiotic resistance - statnews.com
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Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems - Science | AAAS
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Unlocking the Passcodes to Manipulate Natural Bacterial Communities - Department of Energy (.gov)
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Enhancing bioinformatics engineering by utilizing graph therapeutic properties for clinically approved antitoxin drugs in zoonotic diseases - Nature
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The higBA- Type Toxin-Antitoxin System in IncC Plasmids Is a Mobilizable Ciprofloxacin-Inducible System - ASM Journals
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Bioinformatic exploration reveals features of tenpIN family of type III toxin-antitoxin systems in bacteria and viruses - Nature
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The combination of active partitioning and toxin-antitoxin systems is most advantageous for low-copy plasmid fitness - Nature
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Chaperone addiction of toxin–antitoxin systems - Nature
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Phages carry orphan antitoxin-like enzymes to neutralize the DarTG1 toxin-antitoxin defense system - Nature
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Understanding the physiological role and cross-interaction network of VapBC35 toxin-antitoxin system from Mycobacterium tuberculosis - Nature
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Auxiliary interfaces support the evolution of specific toxin–antitoxin pairing - Nature
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Mechanisms of neutralization of toxSAS from toxin–antitoxin modules - Nature
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Molecular stripping underpins derepression of a toxin–antitoxin system - Nature
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Bacterial retrons encode phage-defending tripartite toxin–antitoxin systems - Nature
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Type I toxin-antitoxin systems contribute to the maintenance of mobile genetic elements in Clostridioides difficile - Nature
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Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila - Nature
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The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA - Nature
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Toxin-antitoxin RNA pairs safeguard CRISPR-Cas systems - Science | AAAS
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Escherichia coli type I toxin TisB exclusively controls proton depolarization following antibiotic induced DNA damage - Nature
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The bacterial Type III toxin-antitoxin system, ToxIN, is a dynamic protein-RNA complex with stability-dependent antiviral abortive infection activity - Nature
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Chromosomal toxin-antitoxin systems in Pseudomonas putida are rather selfish than beneficial - Nature
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An oxygen-sensitive toxin–antitoxin system - Nature
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A toxin-antitoxin system provides phage defense via DNA damage and repair - Nature
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Biology and evolution of bacterial toxin–antitoxin systems - Nature
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A ParDE-family toxin antitoxin system in major resistance plasmids of Enterobacteriaceae confers antibiotic and heat tolerance - Nature
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Deciphering the role of VapBC13 and VapBC26 toxin antitoxin systems in the pathophysiology of Mycobacterium tuberculosis - Nature
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MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding - Nature
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Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism - Nature
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Toxin-Antitoxin Systems in Escherichia coli Influence Biofilm Formation through YjgK (TabA) and Fimbriae - ASM Journals
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Structural insights into chaperone addiction of toxin-antitoxin systems - Nature
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RNA antitoxin SprF1 binds ribosomes to attenuate translation and promote persister cell formation in Staphylococcus aureus - Nature
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Newly discovered toxin-antitoxin system abundant in one-cell organisms - The Pennsylvania State University
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Phylogeny Reveals Novel HipA-Homologous Kinase Families and Toxin-Antitoxin Gene Organizations - ASM Journals
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hipBA toxin-antitoxin systems mediate persistence in Caulobacter crescentus - Nature
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A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria - Nature
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The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis - Nature
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Functional and Biochemical Characterization of the MazEF6 Toxin-Antitoxin System of Mycobacterium tuberculosis - ASM Journals
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de novo Synthesis of a Bacterial Toxin/Antitoxin System - Nature
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Post-segregational Killing and Phage Inhibition Are Not Mediated by Cell Death Through Toxin/Antitoxin Systems - Frontiers
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Genome Mining Shows Ubiquitous Presence and Extensive Diversity of Toxin-Antitoxin Systems in Pseudomonas syringae - Frontiers
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A quinolone N -oxide antibiotic selectively targets Neisseria gonorrhoeae via its toxin–antitoxin system - Nature
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VapBC22 toxin-antitoxin system from Mycobacterium tuberculosis is required for pathogenesis and modulation of host immune response - Science | AAAS
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The Cysteine Protease MaOC1, a Prokaryotic Caspase Homolog, Cleaves the Antitoxin of a Type II Toxin-Antitoxin System - Frontiers
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Distinct type I and type II toxin-antitoxin modules control Salmonella lifestyle inside eukaryotic cells - Nature
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Predicting toxins found in toxin–antitoxin systems with a role in host-induced Burkholderia pseudomallei persistence - Nature
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The Hha-TomB Toxin-Antitoxin System Shows Conditional Toxicity and Promotes Persister Cell Formation by Inhibiting Apoptosis-Like Death in S. Typhimurium - Nature
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Toxin-antitoxin systems in bacterial growth arrest and persistence - Nature
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Type II Toxin-Antitoxin Systems: Evolution and Revolutions - ASM Journals
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A minimal model for gene expression dynamics of bacterial type II toxin–antitoxin systems - Nature
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Growth control switch by a DNA-damage-inducible toxin–antitoxin system in Caulobacter crescentus - Nature
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Directed evolution of SecB chaperones toward toxin-antitoxin systems - PNAS
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Co-expression network analysis of toxin-antitoxin loci in Mycobacterium tuberculosis reveals key modulators of cellular stress - Nature
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A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT - Nature
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Structural insight into the distinct regulatory mechanism of the HEPN–MNT toxin-antitoxin system in Legionella pneumophila - Nature
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Identification and characterization of chromosomal relBE toxin-antitoxin locus in Streptomyces cattleya DSM46488 - Nature
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Artificial Activation of Escherichia coli mazEF and hipBA Toxin–Antitoxin Systems by Antisense Peptide Nucleic Acids as an Antibacterial Strategy - Frontiers
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Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins - Nature
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Mycobacterium tuberculosis Rv0366c-Rv0367c encodes a non-canonical PezAT-like toxin-antitoxin pair - Nature
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A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS - Nature
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Characterization of toxin-antitoxin systems from public sequencing data: A case study in Pseudomonas aeruginosa - Frontiers
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Toward the identification of a type I toxin-antitoxin system in the plasmid DNA of dairy Lactobacillus rhamnosus - Nature
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ClpAP protease is a universal factor that activates the parDE toxin-antitoxin system from a broad host range RK2 plasmid - Nature
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Toxin-antitoxin function fuels antibiotic-resistance research - The Pennsylvania State University
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Conjugative plasmid-encoded toxin–antitoxin system PrpT/PrpA directly controls plasmid copy number - PNAS
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Antitoxin MqsA Represses Curli Formation Through the Master Biofilm Regulator CsgD - Nature
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The Variety in the Common Theme of Translation Inhibition by Type II Toxin–Antitoxin Systems - Frontiers
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Structural and mutational analysis of MazE6-operator DNA complex provide insights into autoregulation of toxin-antitoxin systems - Nature
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The endobacterium of an arbuscular mycorrhizal fungus modulates the expression of its toxin–antitoxin systems during the life cycle of its host - Nature
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Identification of novel mazEF/pemIK family toxin-antitoxin loci and their distribution in the Staphylococcus genus - Nature
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The higBA Toxin-Antitoxin Module From the Opportunistic Pathogen Acinetobacter baumannii – Regulation, Activity, and Evolution - Frontiers
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Newly discovered toxin-antitoxin system abundant in one-cell organisms - Penn State Engineering News
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Identification and first characterization of DinJ-YafQ toxin-antitoxin systems in Lactobacillus species of biotechnological interest - Nature
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Repertoire and Diversity of Toxin – Antitoxin Systems of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli. New Insight of T his Emergent E. coli Pathotype - Frontiers
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A Primary Physiological Role of Toxin/Antitoxin Systems Is Phage Inhibition - Frontiers
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Diverse distribution of Toxin-Antitoxin II systems in Salmonella enterica serovars - Nature
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MazEF Toxin-Antitoxin System-Mediated DNA Damage Stress Response in Deinococcus radiodurans - Frontiers
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Chaperones help TACkle phage infection - ScienceDirect.com
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Structural insights into the PrpTA toxin–antitoxin system in Pseudoalteromonas rubra - Frontiers
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Identification and characterization of the chromosomal yefM-yoeB toxin-antitoxin system of Streptococcus suis - Nature
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A toxin antitoxin system promotes the maintenance of the IncA/C-mobilizable Salmonella Genomic Island 1 - Nature
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Deletion of toxin–antitoxin systems in the evolution of Shigella sonnei as a host-adapted pathogen - Nature
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Antitoxins: novel strategies to target agents of bioterrorism - Nature
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Arbitrium communication controls phage lysogeny through non-lethal modulation of a host toxin–antitoxin defence system - Nature
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Mono- and multidomain defense toxins of the RelE/ParE superfamily - ASM Journals
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Antitoxin strategy may help target other pathogens - EurekAlert!
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A regulatory role for Staphylococcus aureus toxin–antitoxin system PemIK - Nature
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CAL02, a novel antitoxin liposomal agent, in severe pneumococcal pneumonia: a first-in-human, double-blind, placebo-controlled, randomised trial - The Lancet
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Antitoxin strategy may help target other pathogens - Medical Xpress
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YjbH Solubility Controls Spx in Staphylococcus aureus: Implication for MazEF Toxin-Antitoxin System Regulation - Frontiers
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Health Canada Approves NDS for Botulinum Neurotoxin Countermeasure - Global Biodefense
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FDA Approves First Antitoxin to Neutralize All 7 Botulism Serotypes - Global Biodefense
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Prokaryotic toxin–antitoxin stress response loci - Nature
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Stay or Go: Sulfolobales Biofilm Dispersal Is Dependent on a Bifunctional VapB Antitoxin - ASM Journals
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Thomas K. Wood Research Group - The Pennsylvania State University
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The role of PemIK (PemK/PemI) type II TA system from Klebsiella pneumoniae clinical strains in lytic phage infection - Nature
Why This Topic Is Trending
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