Why is "Arachidonic acid" trending?
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Trend Analysis
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- Date: 2026-03-18 05:03:34
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
Arachidonic acid is a polyunsaturated omega−6 fatty acid 20:4(ω−6), or 20:4(5,8,11,14). It is a precursor in the formation of leukotrienes, prostaglandins, and thromboxanes.
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Search Interest Perspective
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Arachidonic acid induces pyroptosis via a non-autophagic function of mitophagy and enhances immunotherapy in a PDAC model - Nature
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Bridging Metabolomics and Nociception: The Arachidonic Acid–NMDA Receptor Axis in Burning Mouth Syndrome - Wiley Online Library
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dsm-firmenich on how brands can inspect ARA suppliers amid global infant formula recalls - Nutrition Insight
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Arachidonic Acid Metabolism Down-Regulation-Mediated Tumor Necrosis Factor Signaling Contributes to Cutaneous Fibrosis and Skull Hyperplasia in Goldfish Hoods | Research - Science Partner Journals
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Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma - Nature
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Arachidonic Acid Mobilization and Peroxidation Promote Microglial Dysfunction in Aβ Pathology - Journal of Neuroscience
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Emerging Roles and Therapeutic Applications of Arachidonic Acid Pathways in Cardiometabolic Diseases - American Heart Association Journals
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Arachidonic Acid Stress Impacts Pneumococcal Fatty Acid Homeostasis - Frontiers
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EU restricts Chinese arachidonic acid oil amid baby formula recalls - Social News XYZ
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Targeting PSMD14 combined with arachidonic acid induces synthetic lethality via FADS1 m - Science | AAAS
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Arachidonate 5-Lipoxygenase Promoter Genotype, Dietary Arachidonic Acid, and Atherosclerosis - The New England Journal of Medicine
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Erigoster B targeting DECR1 induces ferroptosis of breast cancer cells via promoting phosphatidylcholine/arachidonic acid metabolism - Nature
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Therapeutic and Prognostic Significance of Arachidonic Acid in Heart Failure - American Heart Association Journals
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Arachidonic acid is associated with dyslipidemia and cholesterol-related lipoprotein metabolism signatures - Frontiers
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Insights into the special physiology of Mortierella alpina cultured by agar supported solid state fermentation in enhancing arachidonic acid enriched lipid production - Nature
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Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation - Nature
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Identification and verification of biomarkers associated with arachidonic acid metabolism in non-alcoholic fatty liver disease - Nature
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FADS1-arachidonic acid axis enhances arachidonic acid metabolism by altering intestinal microecology in colorectal cancer - Nature
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Association of plasma arachidonic acid levels with a bipolar disorder and the effects of a FADS gene variant - Nature
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ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism - Nature
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Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein - Nature
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Association of Arachidonic Acid-derived Lipid Mediators with Subsequent Onset of Acute Myocardial Infarction in Patients with Coronary Artery Disease | Scientific Reports - Nature
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The deregulation of arachidonic acid metabolism in ovarian cancer - Frontiers
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Accumulation of arachidonic acid-containing phosphatidylinositol at the outer edge of colorectal cancer - Nature
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Impact of serum eicosapentaenoic acid/arachidonic acid ratio on overall survival in lung cancer patients treated with pembrolizumab: a pilot study - Nature
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Arachidonic Acid Derived Lipid Mediators Influence Kaposi’s Sarcoma-Associated Herpesvirus Infection and Pathogenesis - Frontiers
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A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A - Nature
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The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis - Nature
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Carthamus tinctorius L. protects cerebral ischemia/reperfusion injury via arachidonic acid/p53-mediated apoptosis axis - Frontiers
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Adverse effects of excessive dietary arachidonic acid on survival, PUFA-derived enzymatic and non-enzymatic oxylipins, stress response in rainbow trout fry - Nature
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Moderate levels of dietary arachidonic acid reduced lipid accumulation and tended to inhibit cell cycle progression in the liver of Japanese seabass Lateolabrax japonicus - Nature
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Arachidonic acid-derived hydroxyeicosatetraenoic acids are positively associated with colon polyps in adult males: a cross-sectional study - Nature
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Mechano-induced arachidonic acid metabolism promotes keratinocyte proliferation through cPLA2 activity regulation - Wiley
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Somatic mutations in arachidonic acid metabolism pathway genes enhance oral cancer post-treatment disease-free survival - Nature
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Metabolomics unveils the exacerbating role of arachidonic acid metabolism in atherosclerosis - Frontiers
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Arachidonic Acid Metabolism Controls Macrophage Alternative Activation Through Regulating Oxidative Phosphorylation in PPARγ Dependent Manner - Frontiers
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Nitric oxide synthesis stimulated by arachidonic acid accumulation via PPARα in acetylcholine-stimulated gastric mucous cells - Wiley
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Identifying potential biomarkers and molecular mechanisms related to arachidonic acid metabolism in vitiligo - Frontiers
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Increased arachidonic acid-containing phosphatidylcholine is associated with reactive microglia and astrocytes in the spinal cord after peripheral nerve injury - Nature
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[Figure, Arachidonic Acid Pathway Contributed from BioMed Central] - StatPearls - National Institutes of Health (.gov)
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Arachidonic acid elicits a substrate-gated proton current associated with the glutamate transporter EAAT4 - Nature
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The Arachidonic Acid Metabolism Mechanism Based on UPLC-MS/MS Metabolomics in Recurrent Spontaneous Abortion Rats - Frontiers
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Arachidonic Acid Mobilization and Peroxidation Promote Microglial Dysfunction in Aβ Pathology - Journal of Neuroscience
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Lipoprotein(a) concentration is associated with plasma arachidonic acid in subjects with familial hypercholesterolaemia - Cambridge University Press & Assessment
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Cannabinoids Influence Lipid–Arachidonic Acid Pathways in Schizophrenia - Nature
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Genetic propensity to higher arachidonic acid levels linked to lower bipolar disorder risk - News-Medical
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The arachidonic acid metabolite 11β-ProstaglandinF2α controls intestinal epithelial healing: deficiency in patients with Crohn’s disease - Nature
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Imaging Neuroinflammation in Alzheimer's Disease with Radiolabeled Arachidonic Acid and PET - Journal of Nuclear Medicine
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Anti-bacterial and anti-biofilm activities of arachidonic acid against the cariogenic bacterium Streptococcus mutans - Frontiers
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Arachidonic acid promotes skin wound healing through induction of human MSC migration by MT3-MMP-mediated fibronectin degradation - Nature
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Altered neuroinflammatory, arachidonic acid cascade and synaptic markers in postmortem Alzheimer’s disease brain - Nature
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A polymorphism in the fatty acid desaturase-2 gene is associated with the arachidonic acid metabolism in pigs - Nature
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Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer - Nature
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Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid - Nature
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Correction: Effects of paternal arachidonic acid supplementation on offspring behavior and hypothalamus inflammation markers in the mouse | PLOS One - PLOS
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Arachidonic acid found to promote the occurrence of radiation-induced intestinal injury - Medical Xpress
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Cyclooxygenase-2-dependent arachidonic acid metabolites are essential modulators of the intestinal immune response to dietary antigen - Nature
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APOE4 and age affect the brain entorhinal cortex structure and blood arachidonic acid and docosahexaenoic acid levels after mild TBI - Nature
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What Makes Red Meat Less Healthy and How Can We Fix It? - News-Medical
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Menopause-induced uterine epithelium atrophy results from arachidonic acid/prostaglandin E2 axis inhibition-mediated autophagic cell death - Nature
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The Lyn/RUVBL1 Complex Promotes Colorectal Cancer Liver Metastasis by Regulating Arachidonic Acid Metabolism Through Chromatin Remodeling - Wiley
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Therapeutic and Prognostic Significance of Arachidonic Acid in Heart Failure | Circulation Research - American Heart Association Journals
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Spadin Selectively Antagonizes Arachidonic Acid Activation of TREK-1 Channels - Frontiers
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Transcriptome data analysis of primary cardiomyopathies reveals perturbations in arachidonic acid metabolism - Frontiers
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Germany Arachidonic Acid Market Size & Outlook, 2021-2030 - Grand View Research
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Yangyinqingfei decoction attenuates PM2.5-induced lung injury by enhancing arachidonic acid metabolism - Frontiers
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Imaging Neuroinflammation in Alzheimer's Disease with Radiolabeled Arachidonic Acid and PET - Journal of Nuclear Medicine
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Chronic Lithium Chloride Administration Attenuates Brain NMDA Receptor-Initiated Signaling via Arachidonic Acid in Unanesthetized Rats - Nature
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Altered arachidonic acid cascade enzymes in postmortem brain from bipolar disorder patients - Nature
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Omega-6 fatty acid may lower bipolar disorder risk, study finds - Medical News Today
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Qishen granules inhibit myocardial inflammation injury through regulating arachidonic acid metabolism - Nature
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Elucidating the molecular mechanisms underlying anti-inflammatory effects of Morchella esculenta in the arachidonic acid metabolic pathway by network pharmacology and molecular docking - Nature
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Two-pronged approach to anti-inflammatory therapy through the modulation of the arachidonic acid cascade - ScienceDirect.com
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TRIM21 Promotes Tumor Growth and Gemcitabine Resistance in Pancreatic Cancer by Inhibiting EPHX1-Mediated Arachidonic Acid Metabolism - Wiley
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Efficacy of Dietary Arachidonic Acid Provided as Triglyceride or Phospholipid as Substrates for Brain Arachidonic Acid Accretion in Baboon Neonates - Nature
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Arachidonic Acid Is a Safe and Efficacious Schistosomicide, and an Endoschistosomicide in Natural and Experimental Infections, and Cysteine Peptidase Vaccinated Hosts - Frontiers
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Arachidonic acid metabolism CYP450 pathway is deregulated in hepatocellular carcinoma and associated with microvascular invasion - Wiley Online Library
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Oncogenic PIK3CA recruits myeloid-derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5-lipoxygenase-dependent arachidonic acid pathway - Wiley Online Library
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Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor - Nature
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The future of pharmacology and therapeutics of the arachidonic acid cascade in the next decade: Innovative advancements in drug repurposing - Frontiers
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Dietary Supplementation of Arachidonic Acid Is Associated with Higher Whole Body Weight and Bone Mineral Density in Growing Pigs - Nature
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The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway - Nature
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Ultrastructural Changes in Human Platelets During Árachidonic Acid-induced Aggregation - ScienceDirect.com
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Tryptophan hydroxylase (TRH) loss of function mutations in Daphnia deregulated growth, energetic, serotoninergic and arachidonic acid metabolic signalling pathways - Nature
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Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels - Nature
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Dietary Long-Chain Polyunsaturated Fatty Acids Minimize Dexamethasone-Induced Reductions in Arachidonic Acid Status But Not Bone Mineral Content in Piglets - Nature
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Omega-6 Fatty Acid Linked to Lower Bipolar Disorder Risk - Neuroscience News
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“A Time to Tear Down and a Time to Mend”: The Role of Eicosanoids in Atherosclerosis - American Heart Association Journals
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Mode of action of mood stabilizers: is the arachidonic acid cascade a common target? - Nature
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Effects of Salmonella Typhimurium infection on intestinal flora and intestinal tissue arachidonic acid metabolism in Wenchang chickens - Frontiers
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Should infant and follow-on formula continue to contain arachidonic acid? - New Food magazine
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Saturated free fatty acids and association with memory formation - Nature
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Maternal Fatty Acid Metabolism in Pregnancy and Its Consequences in the Feto-Placental Development - Frontiers
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Visual Acuity and the Essentiality of Docosahexaenoic Acid and Arachidonic Acid in the Diet of Term Infants - Nature
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Ontogenesis of CYP2C-Dependent Arachidonic Acid Metabolism in the Human Liver: Relationship with Sudden Infant Death Syndrome - Nature
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Fasting May Reduce Inflammation - Neuroscience News
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Potential Antifungal Targets against a Candida Biofilm Based on an Enzyme in the Arachidonic Acid Cascade—A Review - Frontiers
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Exclusive photorelease of signalling lipids at the plasma membrane - Nature
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The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer - Nature
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The Fat Connection: Omega-6 and Triple-Negative Breast Cancer - StudyFinds
Why This Topic Is Trending
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Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.