Why is "Argonaute" trending?

Search Interest Perspective

• Argonaute-HNH filaments triggered by invader DNA confer bacterial immunity - Nature
• Germline fate determination by a single ARGONAUTE protein in Ectocarpus - PNAS
• Harnessing Argonaute 2 as an innovative delivery system for siRNA in glioblastoma treatment - ScienceDirect.com
• Case Report: Neuromyelitis optica spectrum disorder associated with anti-argonaute antibodies presenting with subacute combined degeneration-like features - Frontiers
• Terminal-Optimized Aptamer–Guide-DNAzyme Triplex Boosts Clostridium butyricum Argonaute-Driven Multiplex Foodborne Pathogen Detection without Nucleic Acid Amplification - ACS Publications
• Programmable Argonaute-mediated single-nucleotide variant sequencing of cell-free DNA for multi-cancer early detection - Nature
• Precision Pathogen Detection: Argonaute Powers a New Era of Biosensing - Global Biodefense
• Nobel laureate says treatments for rare genetic disorders now hinge on funding - TVP World
• The Expanded Universe of Prokaryotic Argonaute Proteins - ASM Journals
• Fungal Argonaute proteins act in bidirectional cross-kingdom RNA interference during plant infection - PNAS
• DICER1 hotspot mutation induces 3p microRNA gain of function via Argonaute strand switch - Nature
• Filament assembly induced by the recognition of target DNA activates the prokaryotic Argonaute SPARDA system - Nature
• Endonuclease V activated Pyrococcus furiosus Argonaute for the detection of food contaminated bacteria - Nature
• Activation of the SPARDA defense system by filament assembly using a beta-relay signaling mechanism widespread in prokaryotic Argonautes | Cell Research - Nature
• RNA-guided RNA silencing by an Asgard archaeal Argonaute - Nature
• Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity - Nature
• Dipeptidyl peptidase DPF-3 is a gatekeeper of microRNA Argonaute compensation in animals - Nature
• Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity - Nature
• Structural insights into RNA cleavage by PIWI Argonaute - Nature
• DNA interference and beyond: structure and functions of prokaryotic Argonaute proteins - Nature
• Argonaute proteins: key players in RNA silencing - Nature
• Argonaute protein-based nucleic acid detection technology - Frontiers
• Imaging translational control by Argonaute with single-molecule resolution in live cells - Nature
• Argonaute Proteins: Why Are They So Important for the Legume–Rhizobia Symbiosis? - Frontiers
• Aedes aegypti Argonaute 2 controls arbovirus infection and host mortality - Nature
• Catalytically inactive long prokaryotic Argonaute systems employ distinct effectors to confer immunity via abortive infection - Nature
• Plant virus seed transmission: AGO5-mediated defense and viral counter-defense - Frontiers
• An siRNA-guided ARGONAUTE protein directs RNA polymerase V to initiate DNA methylation - Nature
• An Intricate Network Involving the Argonaute ALG-1 Modulates Organismal Resistance to Oxidative Stress - Nature
• Argonaute-independent, Dicer-dependent antiviral defense against RNA viruses - PNAS
• Tetramerization-dependent activation of the Sir2-associated short prokaryotic Argonaute immune system - Nature
• HRDE-2 drives small RNA specificity for the nuclear Argonaute protein HRDE-1 - Nature
• Nucleic acid mediated activation of a short prokaryotic Argonaute immune system - Nature
• Argonaute Proteins: From Structure to Function in Development and Pathological Cell Fate Determination - Frontiers
• Thermus thermophilus Argonaute-Assisted Nanopore-Encoding Strategy for Multiplexed Mycotoxin Detection - ACS Publications
• Activation mechanism of a short argonaute-TIR prokaryotic immune system - Science | AAAS
• ANCA: artificial nucleic acid circuit with argonaute protein for one-step isothermal detection of antibiotic-resistant bacteria - Nature
• GTSF1 accelerates target RNA cleavage by PIWI-clade Argonaute proteins - Nature
• DNA targeting and interference by a bacterial Argonaute nuclease - Nature
• Importance of an N-terminal structural switch in the distinction between small RNA-bound and free ARGONAUTE - Nature
• RH3 enhances antiviral defense by facilitating small RNA loading into Argonaute 2 at endoplasmic reticulum–chloroplast membrane contact sites - Nature
• Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules - PNAS
• Multiplexed food-borne pathogen detection using an argonaute-mediated digital sensor based on a magnetic-bead-assisted imaging transcoding system - Nature
• Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis - Nature
• Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2 - Nature
• Argonaute proteins: functional insights and emerging roles - Nature
• Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi - Nature
• Argonaute proteins from human gastrointestinal bacteria catalyze DNA-guided cleavage of single- and double-stranded DNA at 37 °C - Nature
• mRNA structural dynamics shape Argonaute-target interactions - Nature
• DNA-targeting short Argonautes complex with effector proteins for collateral nuclease activity and bacterial population immunity - Nature
• Membrane-associated cytoplasmic granules carrying the Argonaute protein WAGO-3 enable paternal epigenetic inheritance in Caenorhabditis elegans - Nature
• Prokaryotic Argonaute Protein from Natronobacterium gregoryi Requires RNAs To Activate for DNA Interference In Vivo - ASM Journals
• In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA - PNAS
• Unraveling a protein that may inspire a new biotechnology tool - Ohio State News
• Distinct roles of Argonaute in the green alga Chlamydomonas reveal evolutionary conserved mode of miRNA-mediated gene expression - Nature
• The evolutionary journey of Argonaute proteins - Nature
• Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute - Nature
• A catalytic function for mammalian Argonautes - Nature
• Argonaute fends off invaders - Nature
• Structural basis of antiphage immunity generated by a prokaryotic Argonaute-associated SPARSA system - Nature
• An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development - Nature
• Argonaute bypasses cellular obstacles without hindrance during target search - Nature
• Unravelling the developmental and functional significance of an ancient Argonaute duplication - Nature
• An Argonaute phosphorylation cycle promotes microRNA-mediated silencing - Nature
• The dynamics of t1 adenosine binding on human Argonaute 2: Understanding recognition with conformational selection - Wiley Online Library
• Arginine methylation promotes siRNA-binding specificity for a spermatogenesis-specific isoform of the Argonaute protein CSR-1 - Nature
• Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system - Nature
• A Hyperthermophilic Argonaute From Ferroglobus placidus With Specificity on Guide Binding Pattern - Frontiers
• Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1 - Nature
• Are Argonaute-Associated Tiny RNAs Junk, Inferior miRNAs, or a New Type of Functional RNAs? - Frontiers
• Mesophilic Argonaute-based isothermal detection of SARS-CoV-2 - Frontiers
• Long-lived microRNA–Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses - PNAS
• Study reveals new details about Argonaute syndromes, a class of neurodevelopmental disorders - Medical Xpress
• DNA-guided genome editing using the Natronobacterium gregoryi Argonaute - Nature
• Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types - Nature
• Crispr/Cas9 Mediated Inactivation of Argonaute 2 Reveals its Differential Involvement in Antiviral Responses - Nature
• No evidence for viral small RNA production and antiviral function of Argonaute 2 in human cells - Nature
• Short prokaryotic Argonautes provide defence against incoming mobile genetic elements through NAD - Nature
• Structure of yeast Argonaute with guide RNA - Nature
• Argonaute proteins couple chromatin silencing to alternative splicing - Nature
• Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein - Nature
• DNA-guided DNA interference by a prokaryotic Argonaute - Nature
• ARGONAUTE PIWI domain and microRNA duplex structure regulate small RNA sorting in Arabidopsis - Nature
• Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module - Science | AAAS
• Guide-independent DNA cleavage by archaeal Argonaute from Methanocaldococcus jannaschii - Nature
• Human Argonaute proteins: To slice or not to slice? - Cold Spring Harbor Laboratory
• Reduced Expression of Argonaute 1, Argonaute 2 and TRBP Changes Levels and Intracellular Distribution of RNAi Factors - Nature
• miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity - Nature
• Profiling Thermus thermophilus Argonaute Guide DNA Sequence Preferences by Functional Screening - Frontiers
• Author Correction: mRNA structural dynamics shape Argonaute-target interactions - Nature
• Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing - PNAS
• Prokaryotic Argonaute from Archaeoglobus fulgidus interacts with DNA as a homodimer - Nature
• Spatial distribution of three ARGONAUTEs regulates the anther phasiRNA pathway - Nature
• Leishmania infection upregulates and engages host macrophage Argonaute 1, and system-wide proteomics reveals Argonaute 1-dependent host response - Frontiers
• Argonaute-2 regulates the proliferation of adult stem cells in planarian - Nature
• Turning catalytically inactive human Argonaute proteins into active slicer enzymes - Nature
• Cell-type-specific profiling of loaded miRNAs from Caenorhabditis elegans reveals spatial and temporal flexibility in Argonaute loading - Nature
• A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality - Nature
• The N domain of Argonaute drives duplex unwinding during RISC assembly - Nature
• A bacterial Argonaute with noncanonical guide RNA specificity - PNAS