Why is "Autophagosome" trending?

Search Interest Perspective

• Model of autophagosome formation containing high-Ca²⁺ ER (IMAGE) - EurekAlert!
• Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance - PNAS
• The E193K LRRK2 mutation interferes with the autophagosome processing through the impairment of the LRRK2-Dynein-1 complex - Nature
• Researchers clarify how cells remove damaged endoplasmic reticulum - Phys.org
• HOPS-dependent vesicle tethering lock inhibits endolysosomal fusions and autophagosome secretion upon the loss of Syntaxin17 - Science | AAAS
• Autophagosome-lysosome mediated secretion of the thrombopoietin receptor is modulated by distinct driver mutations of myeloproliferative neoplasm | Leukemia - Nature
• Aerobic Exercise Attenuates Autophagy-Lysosomal Flux Deficits via β2-AR-Mediated ESCRT-III Subunit CHMP4B in Mice With Human MAPT P301L - Wiley Online Library
• The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion - PNAS
• Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics - Rockefeller University Press
• Initial Steps in Mammalian Autophagosome Biogenesis - Frontiers
• Correction: Osthole induces accumulation of impaired autophagosome against pancreatic cancer cells - Nature
• Autophagic stress activates distinct compensatory secretory pathways in neurons - PNAS
• Mechanisms governing autophagosome biogenesis - Nature
• Autophagosome formation: core machinery and adaptations - Nature
• A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers - Nature
• Machinery, regulation and pathophysiological implications of autophagosome maturation - Nature
• Local membrane source gathering by p62 body drives autophagosome formation - Nature
• Phase separation organizes the site of autophagosome formation - Nature
• The plant unique ESCRT component FREE1 regulates autophagosome closure - Nature
• p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response - Nature
• Deacetylated SNAP47 recruits HOPS to facilitate autophagosome-lysosome fusion independent of STX17 - Nature
• The emerging roles of autophagy in the homeostasis of lysosome-related organelles - Frontiers
• A conserved membrane curvature-generating protein is crucial for autophagosome formation in fission yeast - Nature
• Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation - Nature
• Plant AtEH/Pan1 proteins drive autophagosome formation at ER-PM contact sites with actin and endocytic machinery - Nature
• mTOR-mediated phosphorylation of VAMP8 and SCFD1 regulates autophagosome maturation - Nature
• Scientists capture organelle's transfer between cellular transport tracks for the first time - 동아사이언스
• Phosphatidylinositol-4-phosphate controls autophagosome formation in Arabidopsis thaliana - Nature
• Reconstitution of autophagosome nucleation defines Atg9 vesicles as seeds for membrane formation - Science | AAAS
• Porphyromonas gingivalis, a periodontal pathogen, impairs post-infarcted myocardium by inhibiting autophagosome–lysosome fusion | International Journal of Oral Science - Nature
• Structure, lipid scrambling activity and role in autophagosome formation of ATG9A - Nature
• Newly uncovered missing link in cellular cleanup can help develop therapeutic strategies for Alzheimer’s, Parkinson's, and Cancer - PIB
• CUHK discovers plant-unique membrane-less compartment that helps resist heat stress - The Chinese University of Hong Kong
• Insights on autophagosome–lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5 - Nature
• Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis - Nature
• Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion - Nature
• The autophagosome: origins unknown, biogenesis complex - Nature
• Autophagosome–lysosome fusion is independent of V-ATPase-mediated acidification - Nature
• Origin of the Autophagosomal Membrane in Plants - Frontiers
• Experimental determination and mathematical modeling of standard shapes of forming autophagosomes - Nature
• Temporal dissection of the roles of Atg4 and ESCRT in autophagosome formation in yeast - Nature
• Gigaxonin E3 ligase governs ATG16L1 turnover to control autophagosome production - Nature
• AMPK contributes to autophagosome maturation and lysosomal fusion - Nature
• Atg2 mediates direct lipid transfer between membranes for autophagosome formation - Nature
• Actin nucleation by WH2 domains at the autophagosome - Nature
• The IAP family member BRUCE regulates autophagosome–lysosome fusion - Nature
• Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice - Nature
• Autophagosome–lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL - Nature
• ATG5 defines a phagophore domain connected to the endoplasmic reticulum during autophagosome formation in plants - Nature
• Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome–lysosome fusion - PNAS
• The STX17-SNAP47-VAMP7/VAMP8 complex is the default SNARE complex mediating autophagosome–lysosome fusion - Nature
• Rab5-dependent autophagosome closure by ESCRT - Rockefeller University Press
• Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway - Nature
• De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics - Nature
• The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation - Nature
• Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation - Rockefeller University Press
• Who plays the ferryman: ATG2 channels lipids into the forming autophagosome - Rockefeller University Press
• Arabidopsis CaLB1 undergoes phase separation with the ESCRT protein ALIX and modulates autophagosome maturation - Nature
• mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy - Nature
• Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy - Science | AAAS
• The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis - Nature
• LAPTM5 Confers the Resistance to Venetoclax via Promoting the Autophagosome-Lysosome Fusion in Multiple Myeloma - Wiley Online Library
• Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles - Nature
• A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3 - Nature
• CHIP ameliorates nonalcoholic fatty liver disease via promoting K63- and K27-linked STX17 ubiquitination to facilitate autophagosome-lysosome fusion - Nature
• Ultrasound-activated in situ click chemistry to trigger autophagosome tracking for enhanced autophagy blockade and synergistic cancer therapy - Wiley Online Library
• Recycling of autophagosomal components from autolysosomes by the recycler complex - Nature
• Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response - Nature
• Disruption of the plant-specific CFS1 gene impairs autophagosome turnover and triggers EDS1-dependent cell death | Scientific Reports - Nature
• couples F-actin mediated mitoaggregate disassembly with autophagosome formation during mitophagy - Nature
• ATG9 regulates autophagosome progression from the endoplasmic reticulum in Arabidopsis - PNAS
• A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation - Nature
• Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy - Rockefeller University Press
• Autophagosomes coated in situ with nanodots act as personalized cancer vaccines - Nature
• Modulation of autophagy by RTN-1C: role in autophagosome biogenesis - Nature
• Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy - Science | AAAS
• A current perspective of autophagosome biogenesis - Nature
• LC3-positive structures are prominent in autophagy-deficient cells - Nature
• A new type of ERGIC–ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis - Nature
• O -GlcNAc-modification of SNAP-29 regulates autophagosome maturation - Nature
• Recent Advances in Membrane Shaping for Plant Autophagosome Biogenesis - Frontiers
• Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth - Nature
• Impaired autophagosome clearance contributes to neuronal death in a piglet model of neonatal hypoxic-ischemic encephalopathy - Nature
• Autophagosome formation: not necessarily an inside job - Nature
• TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway - Nature
• The origin of the autophagosomal membrane - Nature
• SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome–lysosome fusion - Nature
• Unbalanced Regulation of Sec22b and Ykt6 Blocks Autophagosome Axonal Retrograde Flux in Neuronal Ischemia–Reperfusion Injury - Journal of Neuroscience
• Identification of membrane curvature sensing motifs essential for VPS37A phagophore recruitment and autophagosome closure | Communications Biology - Nature
• An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure - Nature
• Actin shapes the autophagosome - Nature
• Vesicular trafficking and autophagosome formation - Nature
• Control of Autophagosome Axonal Retrograde Flux by Presynaptic Activity Unveiled Using Botulinum Neurotoxin Type A - Journal of Neuroscience
• ERdj8 governs the size of autophagosomes during the formation process - Rockefeller University Press
• Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy - Nature
• The good, the bad and the autophagosome: exploring unanswered questions of autophagy-dependent cell death - Nature
• The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formation - PNAS
• Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries - Nature
• Tunneling nanotubes facilitate autophagosome transfer in the leukemic niche - Nature
• ULK phosphorylation of STX17 controls autophagosome maturation via FLNA - Rockefeller University Press