Why is "Baclofen" trending?
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Trend Analysis
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- Date: 2026-03-25 16:54:17
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Wikipedia Overview
Baclofen, sold under the brand names Lioresal, Baclosan, Gablofen among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. Baclofen is a powerful GABA-derivative skeletal muscle relaxant and a potent GABAB receptor agonist. It may also be used for hiccups and muscle spasms near the end of life, and off-label to treat alcohol use disorder or opioid withdrawal symptoms. It is taken orally or by intrathecal pump. It is believed to work by decreasing levels of certain neurotransmitters.
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Study protocol Improving inpatient GHB detoxification with baclofen: a proof of concept and dose-finding study - medRxiv
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Oral Baclofen Toxicity in a Pediatric Patient Managed Without Invasive Intervention: A Case Report and Literature Review - Cureus
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Regional-specific GABAergic imbalance in cisplatin-induced neuropathy and antiallodynic effects of intraplantar baclofen in rats - Nature
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Should Baclofen and Tizanidine Join the Beers Criteria List? - Medscape
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Intrathecal baclofen therapy for spasticity in a person with spinal cord injury and end-stage renal disease dependent on hemodialysis: a case report. - Physician's Weekly
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Care team’s persistence saves social worker’s life - Mayo Clinic News Network
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Amlodipine and Baclofen Overdose Causing Cardiogenic Shock and Mimicking Brain Death: A Novel Combination - Cureus
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Family 'undermined' after Clifton dad's sudden hospital death - BBC
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Caring for patients with intrathecal baclofen pumps - CMAJ
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Baclofen overdose: A curious case of medical sales representative - Gautam - 2022 - Clinical Case Reports - Wiley Online Library
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Baclofen and the Alcohol Withdrawal Syndrome-A Short Review - Frontiers
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Canine baclofen toxicosis - Vet Times
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The presence of Candida parapsilosis with intrathecal baclofen pump in a person with high cervical spinal cord injury; infection or colonization? A Case Report - Nature
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PREDICT-ITB: Predicting response in children with dystonic CP to ITB – study protocol - medRxiv
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Use of O-arm to place an intrathecal catheter through a bony fusion mass: case report - Frontiers
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Bradycardia, Renal Failure, Atrioventricular Nodal Blockade, Shock, and Hyperkalemia (BRASH) Syndrome Associated With Baclofen and Diazepam - Cureus
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The Use of Very High-Doses of Baclofen for the Treatment of Alcohol-Dependence: A Case Series - Frontiers
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Beyond Spasticity: The Dual Impact of Selective Dorsal Rhizotomy in Spastic Quadriplegic Patients With Generalized Dystonia and the Need for Intrathecal Baclofen - Cureus
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Stiff-Person Syndrome: A Case Report and Treatment Modalities - Cureus
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Low-Dose Baclofen-Induced Encephalopathy in a Healthy Young Adult: Is Baclofen Toxicity Dose-Dependent? - Cureus
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Flipping the script: Conservative management of a flipped intrathecal baclofen pump - Archibold - PM&R - Wiley Online Library
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Coma With Absent Brainstem Reflexes and a Burst Suppression on EEG Secondary to Baclofen Toxicity - Frontiers
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Muscle Relaxants Baclofen and Tizanidine Tied to Higher Injury Risk in Older Adults: Study - Medical Dialogues
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Managing Complications of Intrathecal Baclofen Therapy - Neurology Advisor
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Baclofen Therapy for Multiple Sclerosis: What to Know - HealthCentral
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Baclofen Improves Excessive Daytime Sleepiness in Narcolepsy - Neurology Advisor
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Long-term results on the suppression of secondary brain injury by early administered low-dose baclofen in a traumatic brain injury mouse model - Nature
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Baclofen Does Not Significantly Improve Rumination Syndrome Symptoms in Children - HCPLive
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65% of Patients Discontinue Therapy Baclofen Within a Year in Study - Multiple Sclerosis News Today
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Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report - Wiley Online Library
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Relaxant withdrawal 'could have led to man's death' - BBC
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Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson’s disease - Nature
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Baclofen Administered With Opioids Increases Risk for Opioid Overdose - Clinical Pain Advisor
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Baclofen cost 2026: Coupons and more - Medical News Today
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Management of acute overdose or withdrawal state in intrathecal baclofen therapy - Nature
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Efficacy of multimodal treatment involving Baclofen, pelvic floor physiotherapy and polysomnography for sleep related painful erections (SRPE): a single centre observational cohort study - Nature
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Scar Tissue Catheter Tip Occlusion From an Intrathecal Baclofen Delivery: A Case Report and Review of the Literature - Cureus
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Successful Treatment of Idiopathic Intractable Hiccup With Baclofen and Supportive Treatment: A Case Report - Psychiatry Online
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R -Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice - Nature
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Baclofen for the Treatment of Alcohol Use Disorder in Patients With Liver Cirrhosis: 10 Years After the First Evidence - Frontiers
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Two-Needle Approach to Replenish an Empty Intrathecal Pump - Cureus
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Baclofen for the Treatment of Alcohol Use Disorder - American Academy of Family Physicians | AAFP
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Back Off the Baclofen: Increased Risk of Encephalopathy - The Hospitalist
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Is baclofen effective for narcolepsy? - Medical News Today
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Suppressing Effect of Baclofen on Multiple Alcohol-Related Behaviors in Laboratory Animals - Frontiers
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MS Spasticity Therapy Baclofen Helps to Repair Myelin: Early Study - Multiple Sclerosis News Today
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Effects of Baclofen on Cocaine Self-Administration: Opioid- and Nonopioid-Dependent Volunteers - Nature
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Baclofen acts in the central amygdala to reduce synaptic transmission and impair context fear conditioning - Nature
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Baclofen: the controversial pill that could 'cure' alcoholism - The Guardian
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Combining Baclofen with Omeprazole May Further Reduce GERD Symptoms - Pharmacy Times
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Effects of chronic baclofen use on active movement in an individual with a spinal cord injury - Nature
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Case report: Intrathecal baclofen therapy improved gait pattern in a stroke patient with spastic dystonia - Frontiers
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GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism | Neuropsychopharmacology - Nature
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Results of Intrathecal Baclofen Treatment in Sixteen Spasticity Patients According to Four Different Measurement Scales: A Retrospective Analysis - Cureus
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Lioresal (baclofen) for Muscle Spasms in Multiple Sclerosis - Multiple Sclerosis News Today
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Managing loss of intrathecal baclofen efficacy: Review of the literature and proposed troubleshooting algorithm - Neurology® Journals
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High-Dose Baclofen and Mania: What’s the Link? - Medical Professionals Reference
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The incidence and management of tolerance in intrathecal baclofen therapy - Nature
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Intrathecal Baclofen Infusion Pump for the Treatment of Painful Spastic Hemiplegia: A Case Report - Cureus
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Muscle relaxant recalled due to risk of sub-therapeutic dosing - thepharmacist.co.uk
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Baclofen Oral Suspension Approved for Treatment of Spasticity in Multiple Sclerosis - NeurologyLive
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Delirium secondary to intrathecal baclofen - Nature
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Subdural catheter migration may lead to baclofen pump dysfunction - Nature
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Use of Baclofen for Alcohol Use Disorders in the United States - Frontiers
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Structure of Protonated Baclofen [AuCl4]−, Theoretical Elucidation and Biological Studies - Wiley Online Library
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Safety Challenges of Using High Dose Baclofen for Alcohol Use Disorder: A Focused Review - Frontiers
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'Missed opportunities' before dad's sudden death - BBC
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A Case of Meige Syndrome Treated With Baclofen - Cureus
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Baclofen toxicity presenting as myoclonic status epilepticus - Neurology® Journals
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WVU Medicine Children’s implants first intrathecal baclofen pump for treatment of spasticity - WVU Medicine
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Managing loss of intrathecal baclofen efficacy - Neurology® Journals
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Short-Term Use of Baclofen Leading to Delirium in a Patient With End Stage Renal Disease Receiving Hemodialysis - Cureus
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Baclofen Benefits Cirrhosis, Alcohol-Associated Hepatitis Outcomes in AUD - HCPLive
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Subarachnoid haemorrhage: an unusual complication of implantation of an intrathecal baclofen pump - Nature
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Baclofen, Naltrexone, and Sorbitol All Contribute to the Efficacy of PXT3003 in CMT1A Rats - European Medical Journal
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Patients with baclofen pumps may safely undergo transcutaneous spinal stimulation - EurekAlert!
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Baclofen Overdose: What Neurologists Need to Know - NeurologyLive
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Modulation of Motor Cortex Activity After Intrathecal Baclofen Delivery in Chronic Thoracic Spinal Cord Injury - Frontiers
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A Case Report of Baclofen- and Clozapine-Induced Dyskinesia: A Movement Disorder - Cureus
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An Uncommon Side Effect of Baclofen Withdrawal in End Stage Renal Disease - Cureus
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Intrathecal Baclofen for the Treatment of Dystonia in Patients with Reflex Sympathetic Dystrophy - NEJM
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Permanent mechanical deformation of an intrathecal baclofen pump secondary to scuba diving: a case report - Nature
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Nexus Pharmaceuticals Launches Baclofen Injection Refill Kit - BioSpace
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Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion - Nature
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Lyvispah, Dissolvable Baclofen for MS Spasticity, Now Available in US - Multiple Sclerosis News Today
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Common muscle relaxant could pose mental dangers for seniors - upi.com
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Selective Effects of Baclofen on Use-Dependent Modulation of GABAB Inhibition after Tetraplegia - Journal of Neuroscience
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R(+)-Baclofen, but Not S(−)-Baclofen, Alters Alcohol Self-Administration in Alcohol-Preferring Rats - Frontiers
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Further Research Needed to Optimize Benefit of Gabapentin, Baclofen in Chronic Cough - The American Journal of Managed Care® (AJMC®)
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Suppression of Alcohol Dependence Using Baclofen: A 2-Year Observational Study of 100 Patients - Frontiers
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Saol Therapeutics Announces FDA Approval of LYVISPAH™ (baclofen) Oral Granules and the Divesture of its Plasma-derived Hyperimmune Portfolio - PR Newswire
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Certain medications are better than others for managing spine pain - Harvard Health
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Delayed complications of discontinuation of intrathecal baclofen therapy: resurgence of dyssynergic voiding, which triggered off autonomic dysreflexia and hydronephrosis - Nature
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Hemodialysis as emergency treatment of a severe baclofen intoxication in a 3 kg dog - Wiley Online Library
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Camber Adds 5 mg Strength to Their Baclofen Portfolio - Pharmacy Times
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Nipping Cue Reactivity in the Bud: Baclofen Prevents Limbic Activation Elicited by Subliminal Drug Cues - Journal of Neuroscience
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Receptors After Cerebral Ischemia Restores Receptor Expression and Function and Limits Progressing Loss of Neurons - Frontiers
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Prometra II Pump Approved for Use With Spasticity Treatment Baclofen - NeurologyLive
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Oral baclofen administration in persons with chronic spinal cord injury does not prevent the protective effects of spasticity on body composition and glucose homeostasis - Nature
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Ideal Candidates for ITB Pump | NeurologyLive - Clinical Neurology News and Neurology Expert Insights - NeurologyLive
Why This Topic Is Trending
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Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.