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Jame Gumb is a fictional character and the main antagonist of Thomas Harris's 1988 novel The Silence of the Lambs and its 1991 film adaptation, in which he is played by Ted Levine. In the film and the novel, he is a serial killer who lures, kidnaps, and skins women for the purpose of making a "woman suit" to fulfill his desire of female transformation. In the television series Clarice, he is portrayed by Simon Northwood.
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