Why is "CD36" trending?

Search Interest Perspective

• An African ancestry-specific nonsense variant in CD36 is associated with a higher risk of dilated cardiomyopathy - Nature
• Interplay Between Thrombospondin-1 and CD36 Modulates Platelet–RBC Interaction in Thrombosis and Abdominal Aneurysm Formation - American Heart Association Journals
• The role of CD36 in immune function: bridging innate and adaptive responses - Frontiers
• EVA1A regulates fatty acid transporter CD36 in fatty liver disease - News-Medical
• CD36 Inhibits Triple-Negative Breast Cancer Progression by Transcriptionally Upregulating Caveolin-1 and Promoting Lipid-Reactive Oxygen Species-Related Ferroptosis - Wiley Online Library
• FDA Fast Track Highlights Potential of Metabolic Reprogramming in HCC - Targeted Oncology
• Unmasking a Genetic Driver of Dilated Cardiomyopathy in People of African Ancestry - Cleveland Clinic
• Pilatus raises $14M to fund first-in-human study of anti-CD36 mAb - FirstWord Pharma
• CD36 enhances sensitivity of triple negative breast cancer cells to palmitate-induced ferroptosis | Cell Death & Disease - Nature
• Inhibiting CD36 palmitoylation improves cardiac function post-infarction by regulating lipid metabolic homeostasis and autophagy - Nature
• Just Say NO to CD36 Expression: A Regulatory Pathway With Implications in Many Chronic Diseases - American Heart Association Journals
• Identification of new selective CD36 inhibitors to potentiate HER2-targeted therapy in HER2-positive breast cancer - Nature
• PLIN2 promotes colorectal cancer progression through CD36-mediated epithelial-mesenchymal transition - Nature
• Just Say NO to CD36 Expression: A Regulatory Pathway With Implications in Many Chronic Diseases - American Heart Association Journals
• High CD36 expression in the tumor microenvironmental vasculature correlates with unfavorable overall survival in high grade serous ovarian cancer - Nature
• CD36 loss-of-function variant underlies dilated cardiomyopathy risk in African ancestry - Nature
• Elevated CD36 drives lymph node metastasis of breast cancer by activating Hippo-YAP signaling-mediated anoikis resistance - Nature
• PLT012 Receives IND Clearance from FDA for Solid Tumors - Targeted Oncology
• FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes | Circulation Research - American Heart Association Journals
• Author Correction: Absence of CD36 alters systemic vitamin A homeostasis - Nature
• EVA1A Regulates Hepatic Lipid Homeostasis by Modulating CD36 Expression and Its Palmitoylation - Science Partner Journals
• Pilatus teams up with Roche to test anti-CD36 mAb with Tecentriq in HCC - FirstWord Pharma
• PLT012 Receives FDA Fast Track Designation for Liver Cancer Treatment - Cure Today
• Pilatus Biosciences Announces First Patient Dosed in Phase 1 Trial of First-in-Class Metabolic Checkpoint Antibody PLT012 in Solid Tumors - BioSpace
• Adipocytes regulate monocyte development through the OGT-NEFA-CD36/FABP4 pathway in high-fat diet-induced obesity - Nature
• Common gene variant linked to higher heart disease risk in people with African ancestry - Medical Xpress
• Pilatus Biosciences Announces FDA Clearance of IND Application for PLT012, a First-in-Class Anti-CD36 Metabolic Checkpoint Antibody in Solid Tumors - BioSpace
• CD36-mediated metabolic crosstalk between tumor cells and macrophages affects liver metastasis - Nature
• Nitrosation of CD36 Regulates Endothelial Function and Serum Lipids - American Heart Association Journals
• CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate - Rockefeller University Press
• Why the Diabetic Heart Is Fatty - American Heart Association Journals
• Study Identifies Gene Variant That Increases Heart Failure Risk in People of African Ancestry - Cleveland Clinic Newsroom
• Pilatus Biosciences Announces Issuance of Foundational Global Patent Covering Novel CD36-Targeted Immunotherapy - Yahoo Finance
• Scientists Hack Cell Entry to Supercharge Cancer Drugs - medschool.duke.edu
• Endothelial Stiffening Induced by CD36-Mediated Lipid Uptake Leads to Endothelial Barrier Disruption and Contributes to Atherosclerotic Lesions - American Heart Association Journals
• Haplotypes analysis reveals the genetic basis of type I CD36 deficiency - Nature
• Adipocyte-derived factors induce adherent to suspension transition in breast and pancreatic cancer cells through lipid metabolic alteration - Nature
• The activated CD36-Src axis promotes lung adenocarcinoma cell proliferation and actin remodeling-involved metastasis in high-fat environment | Cell Death & Disease - Nature
• Bypassing Size Constraints, Scientists Use CD36 Protein to Deliver Bulky PROTACs - Genetic Engineering and Biotechnology News
• CD36 Senses Dietary Lipids and Regulates Lipids Homeostasis in the Intestine - Frontiers
• The polymorphism analysis for CD36 among platelet donors - Nature
• CD36 mediates SARS-CoV-2-envelope-protein-induced platelet activation and thrombosis - Nature
• The regulatory role of CD36 in hematopoiesis beyond fatty acid uptake - ScienceDirect.com
• SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia - Nature
• UT Health San Antonio scientists pioneer drug-discovery breakthrough for large and polar drugs - UT Health San Antonio
• Preventing the Fatty Acid-Transporter CD36 From Taking its Toll on the Heart - American Heart Association Journals
• Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection - Nature
• Hidden features: CD36/SR-B2, a master regulator of macrophage phenotype/function through metabolism - Frontiers
• Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36 - Nature
• Endothelial cell CD36 regulates membrane ceramide formation, exosome fatty acid transfer and circulating fatty acid levels - Nature
• CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis - Nature
• Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells - Nature
• The function of CD36 in Mycobacterium tuberculosis infection - Frontiers
• CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis - Nature
• CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis - Nature
• TRIPLE Score: GPVI and CD36 Expression Predict a Prothrombotic Platelet Function Phenotype - American Heart Association Journals
• Ischemic Conditioning Promotes Transneuronal Survival and Stroke Recovery via CD36-Mediated Efferocytosis - American Heart Association Journals
• Role of CD36 in cancer progression, stemness, and targeting - Frontiers
• Is the suppression of CD36 a promising way for atherosclerosis therapy? - ScienceDirect.com
• Assessing CD36 and CD47 expression levels in solid tumor indications to stratify patients for VT1021 treatment - Nature
• T cell homeostasis in acute Stanford type-A aortic dissection - Nature
• Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8 - Nature
• Pilatus Biosciences Publishes Preclinical Data in Cancer Discovery on PLT012 First-in-Class CD36-Targeting Antibody for Liver Cancer - BioSpace
• CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors - Nature
• Evidence that CD36 is expressed on red blood cells and constitutes a novel blood group system of clinical importance - Wiley Online Library
• Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses - American Heart Association Journals
• Pilatus Biosciences Enters Clinical Collaboration with Roche - European Biotechnology Magazine
• Immune Regulation of the Liver Through the PCSK9/CD36 Pathway During Heart Transplant Rejection - American Heart Association Journals
• CD36 neutralisation blunts TLR2-IRF7 but not IRF3 pathway in neonatal mouse brain and immature human microglia following innate immune challenge | Scientific Reports - Nature
• CD36 promotes NLRP3 inflammasome activation via the mtROS pathway in renal tubular epithelial cells of diabetic kidneys - Nature
• Six genetically linked mutations in the CD36 gene significantly delay the onset of Alzheimer's disease - Nature
• The computational analyses, molecular dynamics of fatty-acid transport mechanism to the CD36 receptor - Nature
• CD36 deficiency inhibits proliferation by cell cycle control in skeletal muscle cells - Frontiers
• Release of CD36-associated cell-free mitochondrial DNA and RNA as a hallmark of space environment response - Nature
• CD36 family members are TCR-independent ligands for CD1 antigen–presenting molecules - Science | AAAS
• Scientists develop immunotherapy to disarm fat-fuelled tumours - Drug Target Review
• A systematic review and meta-analysis on the association between CD36 rs1761667 polymorphism and cardiometabolic risk factors in adults - Nature
• Targeting metastasis-initiating cells through the fatty acid receptor CD36 - Nature
• CD36 is a co-receptor for hepatitis C virus E1 protein attachment - Scientific Reports - Nature
• The structural basis for CD36 binding by the malaria parasite - Nature
• Early-life stress perturbs the epigenetics of Cd36 concurrent with adult onset of NAFLD in mice - Nature
• Combined Blockade of Lipid Uptake and Synthesis by CD36 Inhibitor and SCD1 siRNA Is Beneficial for the Treatment of Refractory Prostate Cancer - Wiley
• A role for CD36 in the regulation of dendritic cell function - PNAS
• TRPM2 deficiency in mice protects against atherosclerosis by inhibiting TRPM2–CD36 inflammatory axis in macrophages - Nature
• CD36+ cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor | Cell Discovery - Nature
• Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure - Nature
• CD36, a scavenger receptor implicated in atherosclerosis - Nature
• Immunometabolic modulation of retinal inflammation by CD36 ligand - Nature
• Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma - Nature
• Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis - Nature
• UT Health San Antonio-led discovery means IV medication could be taken orally for range of cancer, Alzheimer’s treatments - UT Health San Antonio
• Drug uptake discovery could allow IV medications to be taken orally - Medical Xpress
• CD36 cell surface expression as a surrogate marker to identify ABL/JAK-class kinase fusions in pediatric BCP-ALL - Nature
• Macrophage-derived CD36 + exosome subpopulations as novel biomarkers of Candida albicans infection - Nature
• Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy - Nature
• Contribution of rare coding mutations in CD36 to type 2 diabetes and cardio-metabolic complications - Nature
• A CD36 ectodomain mediates insect pheromone detection via a putative tunnelling mechanism - Nature
• A drug to block fat intake and combat cancer spread - Nature
• CD36 is Associated With the Development of Coronary Artery Lesions in Patients With Kawasaki Disease - Frontiers
• Humanized antibody dismantles metabolic barrier as a potential cancer immunotherapy - News-Medical