Why is "CXC chemokine" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-25 00:08:42
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
Chemokines, or chemotactic cytokines, are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells. In addition to playing a major role in the activation of host immune responses, chemokines are important for biological processes, including morphogenesis and wound healing, as well as in the pathogenesis of diseases like cancers.
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Trending Topic Today
Search Interest Perspective
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CXC Chemokine-Driven Vascular Reprogramming: Modulating Tumor Vasculature to Boost Therapeutic Response - Wiley
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T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours - Nature
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Systemic Inflammatory Stimulus Potentiates the Acute Phase and CXC Chemokine Responses to Experimental Stroke and Exacerbates Brain Damage via Interleukin-1- and Neutrophil-Dependent Mechanisms - Journal of Neuroscience
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Targeting CXCR4 (CXC Chemokine Receptor Type 4) for Molecular Imaging of Aldosterone-Producing Adenoma - ahajournals.org
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Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices - PNAS
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CXC chemokine ligand 16: a Swiss army knife chemokine in cancer - Cambridge University Press & Assessment
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Structural basis of CXC chemokine receptor 2 activation and signalling - Nature
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Structural basis of CXC chemokine receptor 1 ligand binding and activation - Nature
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Hypoxia-induced CXC chemokine ligand 14 expression drives protumorigenic effects through activation of insulin-like growth factor-1 receptor signaling in glioblastoma - Wiley Online Library
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Structural insights into the activation and inhibition of CXC chemokine receptor 3 - Nature
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Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells - Nature
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CXC chemokine ligand 4 (Cxcl4) is a platelet‐derived mediator of experimental liver fibrosis - Wiley Online Library
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Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration - Nature
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Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487 - Nature
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C-terminal–modified LY2510924: a versatile scaffold for targeting C-X-C chemokine receptor type 4 - Nature
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High CXC chemokine receptor 4 expression is an adverse prognostic factor in patients with clear-cell renal cell carcinoma | British Journal of Cancer - Nature
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A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo - Nature
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MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment - Nature
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Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway - Nature
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The role of CXCL family members in different diseases - Nature
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Impairment in Postischemic Neovascularization in Mice Lacking the CXC Chemokine Receptor 3 - ahajournals.org
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Overview of the Mechanisms that May Contribute to the Non-Redundant Activities of Interferon-Inducible CXC Chemokine Receptor 3 Ligands - Frontiers
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Serum proteome profiling detects myelodysplastic syndromes and identifies CXC chemokine ligands 4 and 7 as markers for advanced disease - PNAS
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Transforming growth factor-β1 upregulates the expression of CXC chemokine receptor 4 (CXCR4) in human breast cancer MCF-7 cells - Nature
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CXCL3: A key player in tumor microenvironment and inflammatory diseases - sciencedirect.com
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CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN- γ -independent manner - Nature
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Interleukin-18 Induces Rheumatoid Arthritis Synovial Fibroblast CXC Chemokine Production through NFκB Activation - Nature
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Immunology & Cell Biology | ASI Journal - Wiley Online Library
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The CXC Chemokine GCP-2/CXCL6 Is Predominantly Induced in Mesenchymal Cells by Interleukin-1β and Is Down-Regulated by Interferon-γ: Comparison with Interleukin-8/CXCL8 - Nature
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Identification of the Receptor and Cellular Ortholog of the Marek's Disease Virus (MDV) CXC Chemokine - Frontiers
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.