Why is "CYP2C9" trending?

Search Interest Perspective

• Effects of CYP2C9 genetic polymorphism and drug-drug interactions on trimethoprim metabolism - ScienceDirect.com
• Utilizing CYP2C9 Testing and JAK Inhibitors for Alopecia Areata - Dermatology Times
• Reconstructing the pharmacogenomic landscape of psychiatric medication metabolism in the Indian population - Nature
• A digital twin of glimepiride for personalized and stratified diabetes treatment - Frontiers
• Personalizing Multiple Sclerosis Management: Application of Genomics and CYP2C9 Testing - Neurology Advisor
• Impact of genetic and non-genetic factors on hepatic CYP2C9 expression and activity in Hungarian subjects - Nature
• The clinically relevant CYP2C8*3 and CYP2C9*2 haplotype is inherited from Neandertals - Nature
• Comparative analysis of sex-based, vendor-based, and species differences in cytochrome P450 metabolism - Nature
• Variations in the frequencies of polymorphisms in the CYP2C9 gene in six major ethnicities of Pakistan - Nature
• Modulation of CYP2C9 activity and hydrogen peroxide production by cytochrome b5 | Scientific Reports - Nature
• Frequency of CYP2C9 alleles in Koreans and their effects on losartan pharmacokinetics - Nature
• CYP2C9 and OATP1B1 genetic polymorphisms affect the metabolism and transport of glimepiride and gliclazide - Nature
• Short- and medium-term impact of bariatric surgery on the activities of CYP2D6, CYP3A4, CYP2C9, and CYP1A2 in morbid obesity - Nature
• Suppression of CYP2C9 by MicroRNA hsa-miR-128-3p in Human Liver Cells and Association with Hepatocellular Carcinoma | Scientific Reports - Nature
• Effects of polymorphic variation on the thermostability of heterogenous populations of CYP3A4 and CYP2C9 enzymes in solution - Nature
• Application of rapid genotyping of Warfarin individualized pharmacogenetic variants in Warfarin therapy - Nature
• CYP2C9, CYP2C19, ABCB1 genetic polymorphisms and phenytoin plasma concentrations in Mexican-Mestizo patients with epilepsy - Nature
• A Rapid-ACCE review of CYP2C9 and VKORC1 alleles testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding | Genetics in Medicine - Nature
• CYP2C9 polymorphism analysis in Han Chinese populations: building the largest allele frequency database - Nature
• Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction of CYP2C9, HLA-A and HLA-B with anti-epileptic drugs - Nature
• Genetic Determinants of Response to Warfarin during Initial Anticoagulation - The New England Journal of Medicine
• OATP1B3 (699G>A) and CYP2C9*2, *3 significantly influenced the transport and metabolism of glibenclamide and glipizide - Nature
• New CYP2C9 Testing Guidelines Published by AMP - Inside Precision Medicine
• The Impact of CYP2C9*11 Allelic Variant on the Pharmacokinetics of Phenytoin and (S)‐Warfarin - Wiley
• CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: A HuGEnet™ systematic review and meta-analysis - Nature
• Association analysis of CYP2C9*3 and phenytoin-induced severe cutaneous adverse reactions (SCARs) in Thai epilepsy children - Nature
• Effect of CYP2D6, CYP2C9 and ABCB1 genotypes on fluoxetine plasma concentrations and clinical improvement in children and adolescent patients | The Pharmacogenomics Journal - Nature
• Influence of CYP2C9 polymorphisms, demographic factors and concomitant drug therapy on warfarin metabolism and maintenance dose - Nature
• CYP2C9 and VKORC1 genotyping reagents from Idaho Technology: rapid turn-around, accurate results - Nature
• Functional characterization of 32 CYP2C9 allelic variants - Nature
• Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients - Nature
• Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30 - PLOS
• CYP2C9 Genotype-guided Warfarin Prescribing Enhances the Efficacy and Safety of Anticoagulation: A Prospective Randomized Controlled Study - Wiley
• Neurological toxicity after phenytoin infusion in a pediatric patient with epilepsy: influence of CYP2C9 CYP2C19 and ABCB1 genetic polymorphisms - Nature
• Influence of CYP2C9 genotypes on the formation of a hepatotoxic metabolite of valproic acid in human liver microsomes - Nature
• Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach - Nature
• The FDA Approves Deuruxolitinib for Severe Alopecia in Adults - Dermatology Times
• Cytochrome P4502C9: an enzyme of major importance in human drug metabolism - British Pharmacological Society | Journals
• Cost-Effectiveness of Genotype-Guided Warfarin Dosing for Patients With Atrial Fibrillation - American Heart Association Journals
• Association between CYP metabolizer phenotypes and SSRI induced weight gain - 2 Minute Medicine
• CYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards - Nature
• Pharmacogenetics of CYP2C9 and interindividual variability in anticoagulant response to warfarin - Nature
• Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors - Nature
• BPS Publications - British Pharmacological Society | Journals
• The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels - Nature
• Genetic Determinants of Response to Warfarin during Initial Anticoagulation - The New England Journal of Medicine
• Sun Pharma Launches Deuruxolitinib (Leqselvi) for Severe Alopecia Areata - The Dermatology Digest
• Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study - The Lancet
• Variation in 100 relevant pharmacogenes among emiratis with insights from understudied populations - Nature
• Some of Us Are Part-Neanderthal, And It Could Affect How You Process Medicines - ScienceAlert
• Warfarin pharmacogenetics: development of a dosing algorithm for Omani patients - Nature
• Effects of Khat ( Catha edulis ) use on catalytic activities of major drug-metabolizing cytochrome P450 enzymes and implication of pharmacogenetic variations - Nature
• Pungent ginger components modulates human cytochrome P450 enzymes in vitro - Nature
• Tolterodine is a novel candidate for assessing CYP3A4 activity through metabolic volatiles to predict drug responses - Nature
• Clinical Model for Predicting Warfarin Sensitivity - Nature
• Acute kidney injury interacts with VKORC1 genotype on initiative warfarin dose among heart surgery recipients: a real-world research - Nature
• Bristol Myers Squibb's Zeposia launches into crowded MS market - Fierce Pharma
• Fall Clinical News: Deuruxolitinib Shows Early and Sustained Efficacy in AA - The Dermatology Digest
• Changes in CYP3A4 Enzyme Expression and Biochemical Markers Under Acute Hypoxia Affect the Pharmacokinetics of Sildenafil - Frontiers
• Content and activity of human liver microsomal protein and prediction of individual hepatic clearance in vivo - Nature
• FDA Updates Label for Commonly Used Blood Thinner to Include Dosing Recommendations Based on Genetics - 23andMe Blog
• Effect of Gene-Based Warfarin Dosing on Anticoagulation Control and Clinical Events in a Real-World Setting - Frontiers
• The effect of the VKORC1 promoter variant on warfarin responsiveness in the Saudi WArfarin Pharmacogenetic (SWAP) cohort - Nature
• A randomized controlled trial of genotype-based Coumadin initiation - Genetics in Medicine - Nature
• Creating and validating a warfarin pharmacogenetic dosing algorithm fo | PGPM - Dove Medical Press
• Pharmacogenetics Puzzle - the-scientist.com
• Scotland | Tayside and Central | Diabetes gene link treatment hope - BBC