Why is "Cadherin" trending?

Search Interest Perspective

• β-catenin condensation facilitates clustering of the cadherin/catenin complex and formation of nascent cell-cell junctions - Nature
• Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion - Rockefeller University Press
• VE-Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension-Sensitive Intermediate State - Wiley
• Planar cell polarity protein Vangl2 interacts with M-cadherin and stabilizes its cell surface expression in mouse C2C12 myoblasts - Frontiers
• Systemic delivery of cadherin 17–specific CAR T cells allows effective and safe targeting of colorectal cancer liver metastases - Science | AAAS
• Soluble E-cadherin drives brain metastasis in aggressive inflammatory breast cancer - News-Medical
• Atypical Cadherin FAT2 Is Required for Synaptic Integrity and Motor Behaviors - Journal of Neuroscience
• Novel cadherin conjugates enter the clinic | ApexOnco - Clinical Trials news and analysis - Oncology Pipeline
• Exploratory insights into salivary E-cadherin as a non-invasive biomarker in a rat model of diabetes - Nature
• Antibody-drug conjugates targeting the cadherin, claudin and nectin families of adhesion molecules - Frontiers
• Engineering Cadherin-Guided MSC Aggregates to Empower Synergistic Neurovascular Repair After Stroke - Wiley Online Library
• The functional activity of E-cadherin controls tumor cell metastasis at multiple steps - PNAS
• E-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial monolayers by inducing ADAM-mediated ligand shedding - Science | AAAS
• Generation of a Triple Tag Knock‐In Mouse to Visualize Precise Protein Localization Patterns for Type II Classic Cadherins During Brain Development - Hotta - 2025 - Genes to Cells - Wiley Online Library
• Outside-in engineering of cadherin endocytosis using a conformation strengthening antibody - Nature
• N-cadherin Adhesive Interactions Mechanically Modulate Phenotype of Pancreatic Stellate Cells via YAP-dependent Mechanosensing - Wiley Online Library
• Reversible photoregulation of cell-cell adhesions with opto-E-cadherin - Nature
• N-Cadherin based adhesion and Rac1 activity regulate tension polarization in the actin cortex - Nature
• YAP1 controls the N-cadherin-mediated tumor-stroma interaction in melanoma progression | Oncogene - Nature
• Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance - Nature
• Proximity interactome of lymphatic VE-cadherin reveals mechanisms of junctional remodeling and reelin secretion - Nature
• Expression of E-cadherin by CD8+ T cells promotes their invasion into biliary epithelial cells | Nature Communications - Nature
• Loss of E-cadherin is causal to pathologic changes in chronic lung disease - Nature
• N-Cadherin promotes cardiac regeneration by potentiating pro-mitotic β-Catenin signaling in cardiomyocytes - Nature
• Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension - Nature
• N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity - Nature
• N-cadherin dynamically regulates pediatric glioma cell migration in complex environments - Rockefeller University Press
• Cadherin Signaling in Cancer: Its Functions and Role as a Therapeutic Target - Frontiers
• E-cadherin is required for metastasis in multiple models of breast cancer - Nature
• Programmable integrin and N-cadherin adhesive interactions modulate mechanosensing of mesenchymal stem cells by cofilin phosphorylation - Nature
• Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion - Nature
• Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody - PNAS
• E-cadherin in contact inhibition and cancer - Nature
• Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10 - Nature
• Cadherin cis and trans interactions are mutually cooperative - PNAS
• Development of intensiometric indicators for visualizing N-cadherin interaction across cells | Communications Biology - Nature
• Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface - Nature
• Nucleation of cadherin clusters on cell-cell interfaces - Nature
• Role of E-cadherin in epithelial barrier dysfunction: implications for bacterial infection, inflammation, and disease pathogenesis - Frontiers
• Direct visualization of the extracellular binding structure of E-cadherins in liquid - Nature
• Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT - Nature
• Distinct contributions of tensile and shear stress on E-cadherin levels during morphogenesis - Nature
• E-cadherin staining in the diagnosis of lobular versus ductal neoplasms of the breast: the emperor has no clothes - Wiley Online Library
• Cadherin-11 regulates fibroblast inflammation - PNAS
• Mechanical disruption of E-cadherin complexes with epidermal growth factor receptor actuates growth factor–dependent signaling - PNAS
• Three mechanisms control E-cadherin localization to the zonula adherens - Nature
• An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer - Nature
• Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin - Nature
• Molecular mechanism of VE-cadherin in regulating endothelial cell behaviour during angiogenesis - Frontiers
• Cadherin-11 localizes to focal adhesions and promotes cell–substrate adhesion - Nature
• E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning - Nature
• E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements - Nature
• E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components - PNAS
• Essential cooperation of N-cadherin and neuroligin-1 in the transsynaptic control of vesicle accumulation - PNAS
• EPLIN mediates linkage of the cadherin–catenin complex to F-actin and stabilizes the circumferential actin belt - PNAS
• E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo - Nature
• Cadherin-based intercellular adhesions organize epithelial cell–matrix traction forces - PNAS
• δ-Catenin controls astrocyte morphogenesis via layer-specific astrocyte–neuron cadherin interactions - Rockefeller University Press
• Pancreatic Exocrine Tissue Architecture and Integrity are Maintained by E-cadherin During Postnatal Development - Nature
• A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion - Nature
• N-cadherin antagonism is bronchoprotective in severe asthma models - Science | AAAS
• VE-Cadherin: A Critical Sticking Point for Lymphatic System Maintenance: Role of VE-Cadherin in Lymphatic Maintenance - American Heart Association Journals
• E-cadherin junctions as active mechanical integrators in tissue dynamics - Nature
• Cadherin puncta are interdigitated dynamic actin protrusions necessary for stable cadherin adhesion - PNAS
• E-cadherin loss drives diffuse-type gastric tumorigenesis via EZH2-mediated reprogramming - Rockefeller University Press
• Quantification of topological features in cell meshes to explore E-cadherin dysfunction - Nature
• Vangl2 Regulates E-Cadherin in Epithelial Cells - Nature
• Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA - Nature
• Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex - PNAS
• Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions - PNAS
• Serum Pro‐N‐Cadherin Is a Marker of Subclinical Heart Failure in the General Population - American Heart Association Journals
• The Cross-Talk Between EGFR and E-Cadherin - Frontiers
• Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β - Science | AAAS
• E-cadherin dynamics is regulated by galectin-7 at epithelial cell surface - Nature
• Contact interactions between epitheliocytes and fibroblasts: Formation of heterotypic cadherin-containing adhesion sites is accompanied by local cytoskeletal reorganization - PNAS
• VE-cadherin endocytosis controls vascular integrity and patterning during development - Rockefeller University Press
• Resolving the molecular mechanism of cadherin catch bond formation - Nature
• Decoding the enigmatic role of T-cadherin in tumor angiogenesis - Frontiers
• Mechanisms Ensuring Endothelial Junction Integrity Beyond VE-Cadherin - Frontiers
• Editorial: Non-cadherin based cell adhesion in tissue remodeling - Frontiers
• New evidence for T-cadherin in COVID-19 pathogenesis, endothelial dysfunction, and lung fibrosis - Frontiers
• Cell division orientation is coupled to cell–cell adhesion by the E-cadherin/LGN complex - Nature
• Endocytosis is required for E-cadherin redistribution at mature adherens junctions - PNAS
• Nanoscale architecture of cadherin-based cell adhesions - Nature
• Nervous system–wide analysis of all C. elegans cadherins reveals neuron-specific functions across multiple anatomical scales - Science | AAAS
• The N-cadherin cytoplasmic domain confers anchorage-independent growth and the loss of contact inhibition - Nature
• Late domain dependent E-cadherin recruitment into extracellular vesicles - Frontiers
• N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability | Journal of Cell Biology - Rockefeller University Press
• A role for E-cadherin in ensuring cohesive migration of a heterogeneous population of non-epithelial cells - Nature
• The Premetazoan Ancestry of Cadherins - Science | AAAS
• Three cadherin alleles associated with resistance to Bacillus thuringiensis in pink bollworm - PNAS
• Calcium-dependent dynamics of cadherin interactions at cell–cell junctions - PNAS
• Cadherin 26 is an alpha integrin-binding epithelial receptor regulated during allergic inflammation - Nature
• Beyond E-cadherin: roles of other cadherin superfamily members in cancer - Nature
• Differential Regulation of LPS-Mediated VE-Cadherin Disruption in Human Endothelial Cells and the Underlying Signaling Pathways: A Mini Review - Frontiers
• Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/β-catenin complex - PNAS
• DE-cadherin-mediated cell adhesion is essential for maintaining somatic stem cells in the Drosophila ovary - PNAS
• Nanoscale dynamics of the cadherin–catenin complex bound to vinculin revealed by neutron spin echo spectroscopy - PNAS
• VE-Cadherin Is Required for Cardiac Lymphatic Maintenance and Signaling - American Heart Association Journals
• Linking molecular affinity and cellular specificity in cadherin-mediated adhesion - PNAS