Why is "Calcium oxalate" trending?
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- Date: 2026-03-19 09:55:01
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
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Wikipedia Overview
Calcium oxalate (in archaic terminology, oxalate of lime) is a calcium salt of oxalic acid with the chemical formula CaC2O4 or Ca(COO)2. It forms hydrates CaC2O4·nH2O, where n varies from 1 to 3. Anhydrous and all hydrated forms are colorless or white. The monohydrate CaC2O4·H2O occurs naturally as the mineral whewellite, forming envelope-shaped crystals, known in plants as raphides. The two rarer hydrates are dihydrate CaC2O4·2H2O, which occurs naturally as the mineral weddellite, and trihydrate CaC2O4·3H2O, which occurs naturally as the mineral caoxite, are also recognized. Some foods have high quantities of calcium oxalates and can produce sores and numbing on ingestion and may even be fatal. Cultural groups with diets that depend highly on fruits and vegetables high in calcium oxalate, such as those in Micronesia, reduce the level of it by boiling and cooking them. They are a constituent in 76% of human kidney stones. Calcium oxalate is also found in beerstone, a scale that forms on containers used in breweries.
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Search Interest Perspective
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Effect of calcium oxalate microcrystals on kidney proximal tubule epithelial cell gene expression in microgravity - Nature
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Small molecule drug candidate offers hope for rare kidney stone disease with no current treatment - Medical Xpress
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Researchers discover a previously unknown bacterial component in kidney stone formation - UCLA Health
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Review Supports Fluids, Diet to Prevent Recurrent Kidney Stones - Conexiant
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Targeting the NLRP3 inflammasome for calcium oxalate stones: pathophysiology and emerging pharmacological interventions - Frontiers
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Live bacteria found inside calcium oxalate kidney stones, UCLA-led study reports - Labmate Online
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Surprising Find Inside Kidney Stones Suggests We Were Wrong About How They Form - ScienceAlert
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Bio-inspired multifunctional disruptors of calcium oxalate crystallization - Nature
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In Vivo and In Silico Evaluation of a Polyphenol Fraction Extracted From Argania spinosa L. Press-Cake Against Ethylene Glycol-Induced Calcium Oxalate Urolithiasis in Rats: Biochemical, Histopathological, and Molecular Modeling Analyses - Wiley Online Library
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Supplements Show Potential for Kidney Stone Prevention - Medscape
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Scientists Find Bacteria in a Common Type of Kidney Stone - Labroots
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Adhesion at calcium oxalate crystal surfaces and the effect of urinary constituents - PNAS
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The significance of reactive oxygen species in the formation of calcium oxalate stones and the protective effects of antioxidants on the kidneys - Frontiers
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Bacteria Play Previously Unknown Role in Kidney Stones, Study Finds - ScienceAlert
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Therapeutic potential of Desmodium styracifolium polysaccharide in attenuating nano-calcium oxalate induced renal injury and fibrosis - Nature
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Research progress on the mechanisms of interleukin and chemokine families in driving calcium oxalate nephrolithiasis formation - Frontiers
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Growth regulation of calcium oxalate film for surface protection of carbonate stone heritage - Nature
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PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism | Cell Death & Disease - Nature
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Systematic evaluation for effects of urine pH on calcium oxalate crystallization, crystal-cell adhesion and internalization into renal tubular cells - Nature
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Kidney stones harbour living bacteria: Milestone discovery to help develop treatment - Onmanorama
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Boosting inhibition performance of natural polyphenols for the prevention of calcium oxalate kidney stones through synergistic cooperativity - Nature
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-induced classical pyroptosis pathway promoting renal adhesion on calcium oxalate kidney stone formation - Nature
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Secondary products and molecular mechanism of calcium oxalate degradation by the strain Azospirillum sp. OX-1 - Nature
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Most Kidney Stones May Actually Be Bacterial Colonies - ScienceBlog.com
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The identification of key molecules and pathways in the crosstalk of calcium oxalate-treated TCMK-1 cells and macrophage via exosomes - Nature
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The urinary microbiota composition and functionality of calcium oxalate stone formers - Frontiers
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Traces of calcium oxalate biomineralization in fossil leaves from late Oligocene maar deposits from Germany - Nature
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Chronic liver disease and hepatic calcium-oxalate deposition in patients with primary hyperoxaluria type I - Nature
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Seasonal changes in foliar calcium oxalate concentrations in conifer and hardwood trees: a potentially bioavailable source of cellular calcium and/or oxalate under stress - Frontiers
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The Effects of 24-Hour Urinary Calcium Oxalate Supersaturation Level on Stone Growth and New Stone Formation: "When To Worry, When to Not" Presentation - Antonio R. H. Gorgen - UroToday
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GOLPH3 promotes calcium oxalate-induced renal injury and fibrosis through Golgi stress-mediated apoptosis and inflammatory responses - Nature
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Identifying Two Novel Clusters in Calcium Oxalate Stones With Urinary Tract Infection Using 16S rDNA Sequencing - Frontiers
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Lgals3 Promotes Calcium Oxalate Crystal Formation and Kidney Injury Through Histone Lactylation-Mediated FGFR4 Activation - Wiley
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Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: Contribution to oxalate kidney injury - Nature
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Visualisation of calcium oxalate crystal macropatterns in plant leaves using an improved fast preparation method - Wiley Online Library
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Clinical validation of urinary indole-reacted calcium oxalate crystallization index (iCOCI) test for diagnosing calcium oxalate urolithiasis - Nature
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Randall’s plaque and calcium oxalate stone formation: role for immunity and inflammation - Nature
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Shape-dependent cellular toxicity on renal epithelial cells and stone risk of calcium oxalate dihydrate crystals - Nature
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Macrophage Function in Calcium Oxalate Kidney Stone Formation: A Systematic Review of Literature - Frontiers
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Metformin suppresses calcium oxalate crystal-induced kidney injury by promoting Sirt1 and M2 macrophage-mediated anti-inflammatory activation - Nature
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M1/M2-macrophage phenotypes regulate renal calcium oxalate crystal development - Nature
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[Figure, Calcium Oxalate Monohydrate Crystals. The...] - StatPearls - National Institutes of Health (.gov)
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Inhibitors of Calcium Oxalate Crystallization for the Treatment of Oxalate Nephropathies - Wiley
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HydroZitLa inhibits calcium oxalate stone formation in nephrolithic rats and promotes longevity in nematode Caenorhabditis elegans - Nature
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Calcium oxalate toxicity in renal epithelial cells: the mediation of crystal size on cell death mode - Nature
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Calcium Oxalate Labs, Inc, The Maker of Kidney C.O.P. Introduces "Kidney C.O.P. Starter Pack" - Yahoo Finance
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Intrinsically Disordered Osteopontin Fragment Orders During Interfacial Calcium Oxalate Mineralization - Wiley Online Library
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Controlled Calcium Oxalate Crystals Obtained by Electrocrystallization on Electrospun Polycaprolactone Fibers Loaded with Zarzaparrilla ( Herreria stellata - ACS Publications
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Effects of secretome derived from macrophages exposed to calcium oxalate crystals on renal fibroblast activation - Nature
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Adults with high calcium, oxalate urinary levels may have increased kidney stone risk - Healio
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Geobiology reveals how human kidney stones dissolve in vivo - Scientific Reports - Nature
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Genetic Predisposition to Formation of Calcium Oxalate Renal Calculi - NEJM
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Calcium oxalate crystals increased enolase-1 secretion from renal tubular cells that subsequently enhanced crystal and monocyte invasion through renal interstitium - Nature
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An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury - Frontiers
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EZH2-mediated macrophage-to-myofibroblast transition contributes to calcium oxalate crystal-induced kidney fibrosis - Nature
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Urinary Calcium Oxalate Crystals in Ethylene Glycol Intoxication - NEJM
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Alpha-enolase on apical surface of renal tubular epithelial cells serves as a calcium oxalate crystal receptor - Nature
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Sirtuin1 Suppresses Calcium Oxalate Nephropathy via Inhibition of Renal Proximal Tubular Cell Ferroptosis Through PGC-1α-mediated Transcriptional Coactivation - Wiley
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Controlling Calcium Oxalate Crystal Growth Using Pectin and Sodium Alginate Natural Polymers - Wiley Online Library
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Size-dependent cellular uptake mechanism and cytotoxicity toward calcium oxalate on Vero cells - Nature
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Calciphytoliths (calcium oxalate crystals) analysis for the identification of decayed tea plants ( Camellia sinensis L.) - Nature
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Lactiplantibacillus plantarum Reduced Renal Calcium Oxalate Stones by Regulating Arginine Metabolism in Gut Microbiota - Frontiers
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Unique Pathological Findings of Polarized Calcium Oxalate Crystals in Spondylodiscitis of an ESRD Hemodialysis Patient: A Case Report - Wiley Online Library
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p38 MAPK mediates calcium oxalate crystal-induced tight junction disruption in distal renal tubular epithelial cells - Nature
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Treatment and Prevention of Kidney Stones: An Update - American Academy of Family Physicians | AAFP
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Calcium Oxalate Labs, Inc, The Maker of Kidney C.O.P. Introduces "Kidney C.O.P. Starter Pack" - ACCESS Newswire
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Calcium Oxalate Retinopathy Associated with Generalized Oxalosis: X-Ray Diffraction and Electron Microscopic Studies of Crystal Deposits | IOVS | ARVO Journals - ARVO Journals
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RETRACTED ARTICLE: Sirt3 suppresses calcium oxalate-induced renal tubular epithelial cell injury via modification of FoxO3a-mediated autophagy - Nature
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‘My Urologist Got Me On Crystal Light’: Doctor Says You Should Drink Crystal Light To Prevent Kidney Stones. But Does It Work? - BroBible
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Kidney stone growth through the lens of Raman mapping - Scientific Reports - Nature
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Researchers Propose New Treatment to Prevent Kidney Stones - TMC Houston
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Metabolomics analysis for hydroxy-L-proline-induced calcium oxalate nephrolithiasis in rats based on ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry - Nature
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Elongation factor Tu on Escherichia coli isolated from urine of kidney stone patients promotes calcium oxalate crystal growth and aggregation - Nature
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Calcium Oxalate Labs, Inc. Introduces VELOXATM: Very Low Oxalate Teas for a Healthier Lifestyle* - Yahoo Finance
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Calcium Oxalate Nephrolithiasis in Dogs, Cats, and Humans - DVM360
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Calcium Oxalate Food Poisoning - Centre for Food Safety
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Calcium Oxalate Labs, Inc. Introduces VELOXATM: Very Low Oxalate Teas for a Healthier Lifestyle - newswire.com
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In Situ Liquid-Cell TEM Observation of Multiphase Classical and Nonclassical Nucleation of Calcium Oxalate - Wiley Online Library
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Morphological Conversion of Calcium Oxalate Crystals Into Stones Is Regulated by Osteopontin in Mouse Kidney - Wiley Online Library
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Effects of calcium oxalate monohydrate crystals on expression and function of tight junction of renal tubular epithelial cells | Laboratory Investigation - Nature
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Flagellum Is Responsible for Promoting Effects of Viable Escherichia coli on Calcium Oxalate Crystallization, Crystal Growth, and Crystal Aggregation - Frontiers
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Role of ROS-Induced NLRP3 Inflammasome Activation in the Formation of Calcium Oxalate Nephrolithiasis - Frontiers
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Study of risk factor of urinary calculi according to the association between stone composition with urine component - Nature
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Probiotics and dietary manipulations in calcium oxalate nephrolithiasis: two sides of the same coin? - ScienceDirect.com
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Cell cycle shift from G0/G1 to S and G2/M phases is responsible for increased adhesion of calcium oxalate crystals on repairing renal tubular cells at injured site - Nature
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High Urinary Calcium and Oxalate Levels Linked to Kidney Stones - European Medical Journal
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Induction of retinopathy by fibrillar oxalate assemblies - Nature
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Hydroxyproline increases inflammation and Uropathogenic E. coli (UPEC) infection in female rats - Nature
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A New Route for Indirect Mineralization of Carbon Dioxide–Sodium Oxalate as a Detergent Builder - Nature
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"Success Files", Hosted By Famed Actor Rob Lowe Highlights Kidney C.O.P.® Calcium Oxalate Protector As Pioneer in Health and New Product Discovery - BioSpace
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Kidney Stone Type Shown to Differ by CKD Stage - Renal and Urology News
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Chinese herb Aspidopterys obcordata shows potential in treating kidney stones - Medical Xpress
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Calcium oxalate urolithiasis in mice lacking anion transporter Slc26a6 - Nature
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Researchers propose new treatment to prevent kidney stones - Medical Xpress
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Caffeine prevents kidney stone formation by translocation of apical surface annexin A1 crystal-binding protein into cytoplasm: In vitro evidence | Scientific Reports - Nature
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Intestinal flora may prevent kidney stones - UChicago Medicine
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The spongy fuel that's made from trees - New Scientist
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Influence of a mineral water rich in calcium, magnesium and bicarbonate on urine composition and the risk of calcium oxalate crystallization - Nature
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Potentialities of mass spectrometry on activation energy and secondary reactions determination of calcium oxalate thermal decomposition - Wiley Online Library
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Study overturns what we know about kidney stones - Medical News Today
Why This Topic Is Trending
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