Why is "Carboxyl" trending?
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Trend Analysis
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- Date: 2026-03-13 21:47:02
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
In organic chemistry, a carboxylic acid is an organic acid that contains a carboxyl group attached to an R-group. The general formula of a carboxylic acid is often written as R−COOH or R−CO2H, sometimes as R−C(O)OH with R referring to an organyl group, or hydrogen, or other groups. Carboxylic acids occur widely. Important examples include the amino acids and fatty acids. Deprotonation of a carboxylic acid gives a carboxylate anion.
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Search Interest Perspective
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Carboxyl-switch mediated interface enhancement toward green manufacturing of CF/PEEK composites - ScienceDirect.com
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Near-care assay of plasma glial fibrillary acid protein and ubiquitin carboxyl-terminal hydrolase isozyme L1 with shorter and prolonged duration exercise | Scientific Reports - Nature
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Carboxyl-Guided Ultrafine Zinc-Acetate Templating Enables Closed-Pore Engineering in Coal-Derived Hard Carbon Anodes for High-Performance Sodium-Ion Batteries - Wiley
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nanoparticles for synergistic selective adsorption of lead and cadmium ions from aqueous solutionss - Nature
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Hydrogen atom transfer method selectively transforms carboxylic acids using an inexpensive photocatalyst - Phys.org
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Acetic acid dominates the Carboxylic Acid Market with a 38.9% share. - Market.us
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Jasmonic acid carboxyl methyltransferase: A key enzyme for jasmonate-regulated plant responses - PNAS
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Merging photoredox with nickel catalysis: Coupling of α-carboxyl sp3-carbons with aryl halides - Science | AAAS
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Pd-Catalyzed Intramolecular Vinyl C–H Acylation with Carboxyl Group: A Facile Access to 1-Indenones - Wiley Online Library
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Synthesis of N-acyl sarcosine from vegetable fatty acid as a novel collector and its low-temperature flotation performance and mechanism for apatite - ScienceDirect.com
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Deletion of PTHrP nuclear localization sequence and carboxyl terminus leads to lung dysplasia - Nature
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Carboxyl-functionalized perovskite enables ALD growth of a compact and uniform ion migration barrier - ScienceDirect.com
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Carboxyl Methyltransferase Catalysed Formation of Mono- and Dimethyl Esters under Aqueous Conditions: Application in Cascade Biocatalysis - Wiley Online Library
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Stimuli responsive carboxyl rich carbon photonic ball ink via template assisted light thermal dehydration of monosaccharides | Scientific Reports - Nature
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Carboxyl-richness controls organic carbon preservation during coprecipitation with iron (oxyhydr)oxides in the natural environment - Nature
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Cycling of labile and recalcitrant carboxyl-rich alicyclic molecules and carbohydrates in Baffin Bay - Nature
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Carboxyl ester lipase hybrid 1 ( CEL-HYB1 ) haplotypes confer varying risk for chronic pancreatitis - Nature
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Catalyst-controlled functionalization of carboxylic acids by electrooxidation of self-assembled carboxyl monolayers - Nature
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Covalently modified carboxyl side chains on cell surface leads to a novel method toward topology analysis of transmembrane proteins - Nature
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Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer - Nature
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In situ topographical chemical and electrical imaging of carboxyl graphene oxide at the nanoscale - Nature
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Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor - Nature
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Carboxyl intermediate formation via an in situ-generated metastable active site during water-gas shift catalysis - Nature
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The phosphorylation of carboxyl-terminal eIF2α by SPA kinases contributes to enhanced translation efficiency during photomorphogenesis - Nature
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Constructing chemical stable 4-carboxyl-quinoline linked covalent organic frameworks via Doebner reaction for nanofiltration - Nature
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Chemoselective Caging of Carboxyl Groups for On-Demand Protein Activation with Small Molecules - Wiley Online Library
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Rapid and Scalable Preparation of High-Crystalline Carboxyl-Functionalized Covalent Triazine Frameworks via Friedel-Crafts Reaction - Wiley Online Library
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A small molecule inhibitor of leucine carboxyl methyltransferase-1 inhibits cancer cell survival - Frontiers
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Overview of carboxyl‑terminal modulator protein 1 and its importance in various metabolic regulations (Review) - spandidos-publications.com
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Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling - Science | AAAS
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A novel carboxyl-rich chitosan-based polymer and its application for clay flocculation and cationic dye removal - ScienceDirect.com
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Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice - PNAS
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Carboxyl functionalized double-walled carbon nanotubes for oxygen evolution reaction - ScienceDirect.com
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Response to Comment on “Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling” - Science | AAAS
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Cx43 carboxyl terminal domain determines AQP4 and Cx30 endfoot organization and blood brain barrier permeability - Nature
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Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloids - Frontiers
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Impact of Carboxyl Groups in Graphene Oxide on Chemoselective Alcohol Oxidation with Ultra-Low Carbocatalyst Loading - Nature
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Synthesis of Carboxyl-Functionalized COFs with Alternate Stable β-Ketoenamine and Benzimidazole Linkages: Unraveling Exceptional Solvent Effects for Efficient Uranium Separation - Wiley Online Library
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The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region - PNAS
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Highly sensitive carboxyl-graphene oxide-based surface plasmon resonance immunosensor for the detection of lung cancer for cytokeratin 19 biomarker in human plasma - ScienceDirect.com
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Methylation of reverse osmosis membrane for superior anti-fouling performance via blocking carboxyl groups in polyamide - Nature
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Identification and biophysical characterization of potential phytochemical inhibitors of carboxyl/choline esterase from Helicoverpa armigera for advancing integrated pest management strategies - Nature
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Regulation of PP2A, PP4, and PP6 holoenzyme assembly by carboxyl-terminal methylation - Nature
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Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage - PNAS
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Blue photoluminescence from active carboxyl adatoms on nanoporous anodic alumina films - Nature
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Bacterial Carboxyl-Terminal Processing Proteases Play Critical Roles in the Cell Envelope and Beyond - ASM Journals
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Carboxyl functional group-assisted defects passivation strategy for efficient air-processed perovskite solar cells with excellent ambient stability - ScienceDirect.com
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Ubiquitin carboxyl-terminal hydrolases are required for period maintenance of the circadian clock at high temperature in Arabidopsis - Nature
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In-situ upgrading of Egyptian heavy crude oil using matrix polymer carboxyl methyl cellulose/silicate graphene oxide nanocomposites - Nature
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-Carbon Conjugated Covalent Organic Frameworks for Overall Photocatalytic Hydrogen Peroxide Production - Wiley Online Library
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Abiotic Formation of an Amide Bond via Surface-Supported Direct Carboxyl–Amine Coupling - Wiley Online Library
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with carboxyl-functionalised task-specific ionic liquids - Nature
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Carboxyl- and amino-functionalized molecules modified multi-site MIL-101 for efficient adsorption of rare earth metal ions - ScienceDirect.com
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Technical Comment on “Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling” - Science | AAAS
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On-site detection of fish furunculosis by combining DNAzyme and carboxyl-functionalized graphene - Frontiers
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Effects of Carboxyl or Amino Group Modified InP/ZnS Nanoparticles Toward Simulated Lung Surfactant Membrane - Frontiers
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Enabling Carbonized Polymer Dots with Color-tunable Time-dependent Room Temperature Phosphorescence through Confining Carboxyl Dimer Association - Wiley Online Library
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How to free trapped radicals from carboxyl - Phys.org
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Rechargeable K‐CO2 Batteries with a KSn Anode and a Carboxyl‐Containing Carbon Nanotube Cathode Catalyst - Wiley Online Library
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Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS - Nature
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One-Pot Construction of NHS-Activated Magnetic Particles for Chemoselective Capture of Carboxyl Metabolites - Wiley
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Carboxyl-modified single-walled carbon nanotubes negatively affect bacterial growth and denitrification activity - Nature
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Overexpression of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) delays Alzheimer's progression in vivo - Nature
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A Solid Transformation into Carboxyl Dimers Based on a Robust Hydrogen-Bonded Organic Framework for Propyne/Propylene Separation - Wiley Online Library
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The Arabidopsis RNA Polymerase II Carboxyl Terminal Domain (CTD) Phosphatase-Like1 (CPL1) is a biotic stress susceptibility gene - Nature
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How to free the trapped radicals from the carboxyl? - EurekAlert!
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HECT (Homologous to the E6-AP Carboxyl Terminus)-Type Ubiquitin E3 Ligase ITCH Attenuates Cardiac Hypertrophy by Suppressing the Wnt/β-Catenin Signaling Pathway - American Heart Association Journals
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Magnetic carboxyl functional nanoporous polymer: synthesis, characterization and its application for methylene blue adsorption | Scientific Reports - Nature
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Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins - Nature
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Rechargeable K‐CO2 Batteries with a KSn Anode and a Carboxyl‐Containing Carbon Nanotube Cathode Catalyst - Wiley Online Library
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Coordination via Coplanar Carboxyl and Hydroxyl Groups Toward High Purity TiO - Wiley
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Carboxyl-Terminal Modulator Protein (CTMP), a Negative Regulator of PKB/Akt and v-Akt at the Plasma Membrane - Science | AAAS
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Carboxyl proteinase from Pseudomonas defines a novel family of subtilisin-like enzymes - Nature
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Ubiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosis - Nature
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Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus - Nature
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Carboxyl-CNTs Act as “Defensive Shield” to Boost Proton Insertion for Stable and Fast-Charging Aqueous Zn-Mn Batteries - Wiley Online Library
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Synergistic Effect of Hydroxyl and Carboxyl Groups on Promoting Nanoparticle Occlusion within Calcite - Wiley Online Library
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Single-layer ionic conduction on carboxyl-terminated silane monolayers patterned by constructive lithography - Nature
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Functionalized carboxyl nanoparticles enhance mucus dispersion and hydration - Nature
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Carboxyl-Dominant Oxygen Rich Carbon for Improved Sodium Ion Storage: Synergistic Enhancement of Adsorption and Intercalation Mechanisms - Wiley
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Amino- and carboxyl-terminal domains of Filamin-A interact with CRMP1 to mediate Sema3A signalling - Nature
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Carboxylic Acid-Functionalized Conducting-Polymer Nanotubes as Highly Sensitive Nerve-Agent Chemiresistors - Nature
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Reversible Phase Transition Triggered by Order–Disorder Transformation of Carboxyl Oxygen Atoms Coupled with Distinct Reorientations in [HN(C4H9)3](fumrate)0.5·(fumaric acid)0.5 - ACS Publications
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Chloroflexus aurantiacus acetyl-CoA carboxylase evolves fused biotin carboxylase and biotin carboxyl carrier protein to complete carboxylation activity - ASM Journals
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Carboxyl-terminus of Hsc70 interacting protein mediates 2,5-hexanedione-induced neurofilament medium chain degradation - ScienceDirect.com
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γ-Secretase: Successive Tripeptide and Tetrapeptide Release from the Transmembrane Domain of β-Carboxyl Terminal Fragment - Journal of Neuroscience
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Amidation, Esterification, and Thioesterification of a Carboxyl-Functionalized Covalent Organic Framework - Wiley Online Library
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Syndromic disorder of sex development due to a novel hemizygous mutation in the carboxyl-terminal domain of ATRX - Nature
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Pancreatic lipase–related protein 2 digests fats in human milk and formula in concert with gastric lipase and carboxyl ester lipase - Nature
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Amino acid ester prodrugs conjugated to the α-carboxylic acid group do not display affinity for the L-type amino acid transporter 1 (LAT1) - ScienceDirect.com
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Synthesis and antibacterial activity of tripropeptin C derivatives modified at the carboxyl groups - Nature
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Ubiquitin carboxyl-terminal esterase L1 is not elevated in the serum of concussed rugby players: an observational cross-sectional study - Nature
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Molecular mechanism of the intramembrane cleavage of the β-carboxyl terminal fragment of amyloid precursor protein by γ-secretase - Frontiers
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Antibacterial Activity and Mechanism of Oxidized Bacterial Nanocellulose with Different Carboxyl Content - Wiley Online Library
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Evidence of Carboxyl Modification of Hydrogen-Free Diamond-Like Carbon Films Assisted by Radio Frequency Plasma in Vacuum - Wiley Online Library
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The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators - PNAS
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Grb2 carboxyl-terminal SH3 domain can bivalently associate with two ligands, in an SH3 dependent manner - Nature
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The C=O Bond, Part III: Carboxylic Acids - Spectroscopy Online
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Carboxyl-terminal fusion of E7 into Flagellin shifts TLR5 activation to NLRC4/NAIP5 activation and induces TLR5-independent anti-tumor immunity - Nature
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Protection against doxorubicin-induced myocardial dysfunction in mice by cardiac-specific expression of carboxyl terminus of hsp70-interacting protein - Nature
Why This Topic Is Trending
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Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.