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Cassava brown streak virus disease (CBSD) is a damaging disease of cassava plants, and is especially troublesome in East Africa. It was first identified in 1936 in Tanzania, and has spread to other coastal areas of East Africa, from Kenya to Mozambique. Recently, it was found that two distinct viruses are responsible for the disease: Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV). Both have (+)ss RNA genomes, belong to the genus Ipomovirus in the family Potyviridae, and produce generally similar symptoms in infected plants. Root rot renders the cassava tuber inedible, resulting in severe loss of economic value; therefore, current research focuses on achieving cultivars that do not develop the necrotic rot. This disease is considered to be the biggest threat to food security in coastal East Africa and around the eastern lakes.
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