Why is "Centrosome" trending?

Search Interest Perspective

• Scientists reveal how dividing cells precisely trigger spindle formation - EurekAlert!
• PCM1 coordinates centrosome asymmetry with polarized endosome dynamics to regulate daughter cell fate - Nature
• Cell Cycle-Specific Regulation of Centrosome Clustering Dynamics in Cancer Cells by the Multifunctional Kinesin HSET - Wiley
• CEP76 impairment at the centrosome-cilium interface contributes to a spectrum of ciliopathies - Science | AAAS
• Perinuclear non-centrosomal microtubules direct nuclei dispersion during epithelial morphogenesis - Rockefeller University Press
• Kinetochore-centrosome feedback linking CENP-E and Aurora kinases controls chromosome congression - Nature
• Cell cycle-specific regulation of centrosome clustering dynamics in cancer cells by the multifunctional kinesin HSET - sinica.edu.tw
• NuSAP: The “centriole bodyguard” of the cell - EurekAlert!
• Scientists Uncover Mechanism Behind Precise Spindle Formation in Dividing Cells - Bioengineer.org
• Centrosome protein TAX1BP2 mediates STING-dependent immune response and potentiates anti-PD-1 efficacy in hepatocellular carcinoma - ScienceDirect.com
• What keeps centrioles together: NuSAP's newly mapped role in centrosome integrity - Phys.org
• Impaired Reorganization of Centrosome Structure Underlies Human Infantile Dilated Cardiomyopathy | Circulation - American Heart Association Journals
• A GPER-PKA-Centrin axis regulates centrosome numbers and centriole integrity in colon cancer cells - Nature
• Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity - Science | AAAS
• Polo-Like Kinase 1 Phosphorylation Tunes the Functional Viscoelastic Properties of the Centrosome Scaffold - Wiley
• The DNA replication machinery transmits dual signals to prevent unscheduled licensing and execution of centrosome duplication - Nature
• LIMK2 promotes centrosome clustering and cancer progression by activating MST4-mediated phosphorylation of NPM1 - Nature
• Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction - Nature
• Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis - Nature
• Centrin-POC5 inner scaffold provides distal centriole integrity for sperm flagellar assembly - Science | AAAS
• Protecting centrosomes from fracturing enables efficient cell navigation - Science | AAAS
• Molecular landscape and functional characterization of centrosome amplification in ovarian cancer - Nature
• Uncoordinated centrosome cycle underlies the instability of non-diploid somatic cells in mammals - Rockefeller University Press
• Yeast centrosomes act as organizing centers to promote Polo kinase–mediated adaptation to persistent DNA damage - PNAS
• The Unkempt RNA-binding protein reveals a local translation program in centriole overduplication - Rockefeller University Press
• Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 - Nature
• Aggresome assembly at the centrosome is driven by CP110–CEP97–CEP290 and centriolar satellites - Nature
• Centrosome biogenesis and function: centrosomics brings new understanding - Nature
• Structural mechanisms for centrosomal recruitment and organization of the microtubule nucleator γ-TuRC - Nature
• Centrosomes and cilia: always at the center of the action - Nature
• Microtubule nucleation and γTuRC centrosome localization in interphase cells require ch-TOG - Nature
• Nuclear polarization to the immune synapse facilitates an early transcriptional burst - Science | AAAS
• Piezo mechanosensory channels regulate centrosome integrity and mitotic entry - PNAS
• PCMD-1 stabilizes the PCM scaffold and facilitates centriole separation - Rockefeller University Press
• A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport - Nature
• 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration - Rockefeller University Press
• Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites - Nature
• SH2D4A promotes centrosome maturation to support spindle microtubule formation and mitotic progression - Nature
• Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells - Rockefeller University Press
• Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis - Nature
• Cell Division: Centrosomes Have Separation Anxiety - ScienceDirect.com
• Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes - Science | AAAS
• Centrosomes: Central no more? - ScienceDirect.com
• Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12 - Nature
• The centrosome protein AKNA regulates neurogenesis via microtubule organization - Nature
• Centrosome anchoring regulates progenitor properties and cortical formation - Nature
• Cell cycle–dependent centrosome clustering precedes proplatelet formation - Science | AAAS
• A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4 - Nature
• Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome - Rockefeller University Press
• Centrosome function and assembly in animal cells - Nature
• The conserved Spd-2/CEP192 domain adopts a unique protein fold to promote centrosome scaffold assembly - Science | AAAS
• Epigenetic alterations impede epithelial-mesenchymal transition by modulating centrosome amplification and Myc/RAS axis in triple negative breast cancer cells - Nature
• A CEP215–HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer - Nature
• The ATM and ATR kinases regulate centrosome clustering and tumor recurrence by targeting KIFC1 phosphorylation - Nature
• A USP28–53BP1–p53–p21 signaling axis arrests growth after centrosome loss or prolonged mitosis - Rockefeller University Press
• Centrosome amplification drives chromosomal instability in breast tumor development - PNAS
• A non-canonical function for Centromere-associated protein-E controls centrosome integrity and orientation of cell division - Nature
• Sufu negatively regulates both initiations of centrosome duplication and DNA replication - PNAS
• Centrosome clustering control in osteoclasts through CCR5-mediated signaling - Nature
• DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6 - Nature
• p53 mitotic centrosome localization preserves centrosome integrity and works as sensor for the mitotic surveillance pathway - Nature
• Centrosomes: Hooked on the Nucleus - ScienceDirect.com
• Laser ablation and fluid flows reveal the mechanism behind spindle and centrosome positioning - Nature
• Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay - Nature
• Asymmetry in centrosome maturation revealed through AIR-1 dynamics in the early Caenorhabditis elegans embryo - Nature
• Cell cycle: Driving the centrosome cycle - ScienceDirect.com
• VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis - Nature
• Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses - Nature
• Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification | Cancer Gene Therapy - Nature
• Structure and assembly of the A-C linker connecting microtubule triplets in centrioles - Science | AAAS
• A mechanism for the elimination of the female gamete centrosome in Drosophila melanogaster - Science | AAAS
• Study sheds light on proteins linked to congenital developmental disorders - YaleNews
• Liver kinase B1 regulates the centrosome via PLK1 - Nature
• Oncosuppressive functions of PIDD1 in response to centrosome amplification - Nature
• A conserved role for centriolar satellites in translation of centrosomal and ciliary proteins - Rockefeller University Press
• Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion - Nature
• The phosphorylation of PHF5A by TrkA-ERK1/2-ABL1 cascade regulates centrosome separation - Nature
• Drosophila neuroblasts retain the daughter centrosome - Nature
• DDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression - Nature
• RAB12-LRRK2 complex suppresses primary ciliogenesis and regulates centrosome homeostasis in astrocytes - Nature
• Analysis of the “centrosome-ome” identifies MCPH1 deletion as a cause of centrosome amplification in human cancer - Nature
• Regulated assembly of a supramolecular centrosome scaffold in vitro - Science | AAAS
• Soluble tubulin is significantly enriched at mitotic centrosomes - Rockefeller University Press
• Actin nucleation at the centrosome controls lymphocyte polarity - Nature
• Focus on Centrosome Biology - Royal Society
• The centrosome is an actin-organizing centre - Nature
• Oncogene-like induction of cellular invasion from centrosome amplification - Nature
• Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68 - Nature
• Centrosome-declustering drugs mediate a two-pronged attack on interphase and mitosis in supercentrosomal cancer cells - Nature
• A new face of the centrosome - Nature
• APC/C is an essential regulator of centrosome clustering - Nature
• Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells - PNAS
• JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli - Science | AAAS
• Multiple centrosomes enhance migration and immune cell effector functions of mature dendritic cells - Rockefeller University Press
• Primary cilium-dependent cAMP/PKA signaling at the centrosome regulates neuronal migration - Science | AAAS
• Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1 - Nature
• Emerging roles of the centrosome in neuronal development - Meka - 2020 - Cytoskeleton - Wiley Online Library
• Autophagy controls centrosome number by degrading Cep63 - Nature
• Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold - Nature
• NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability - PNAS