Why is "Chemogenomics" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-25 00:34:48
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
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Wikipedia Overview
Chemogenomics, or chemical genomics, is the systematic screening of targeted chemical libraries of small molecules against individual drug target families with the ultimate goal of identification of novel drugs and drug targets. Typically some members of a target library have been well characterized where both the function has been determined and compounds that modulate the function of those targets have been identified. Other members of the target family may have unknown function with no known ligands and hence are classified as orphan receptors. By identifying screening hits that modulate the activity of the less well characterized members of the target family, the function of these novel targets can be elucidated. Furthermore, the hits for these targets can be used as a starting point for drug discovery. The completion of the human genome project has provided an abundance of potential targets for therapeutic intervention. Chemogenomics strives to study the intersection of all possible drugs on all of these potential targets.
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Trending Topic Today
Search Interest Perspective
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Chemogenomics for NR1 nuclear hormone receptors - Nature
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Editorial: Computational chemogenomics: In silico tools in pharmacological research and drug discovery - Frontiers
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Chemogenomic profiling: Identifying the functional interactions of small molecules in yeast - pnas.org
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Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics - Science | AAAS
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A review on computer-aided chemogenomics and drug repositioning for rational COVID-19 drug discovery - Wiley Online Library
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Chemogenomics for steroid hormone receptors (NR3) - Nature
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An open source plant kinase chemogenomics set - Ercoli - 2022 - Plant Direct - Wiley Online Library
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Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures - Science | AAAS
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Chemogenomics: an emerging strategy for rapid target and drug discovery - Nature
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Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention - Wiley
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Curation of chemogenomics data - Nature
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Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery | Scientific Reports - Nature
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Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics - Nature
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Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets - Nature
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Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells - Nature
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Cardiovascular Disease Chemogenomics Knowledgebase-guided Target Identification and Drug Synergy Mechanism Study of an Herbal Formula - Nature
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Chemogenomic screening identifies the Hsp70 co-chaperone DNAJA1 as a hub for anticancer drug resistance - Nature
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Multivariate chemogenomic screening prioritizes new macrofilaricidal leads - Nature
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Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks - Nature
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A comparative chemogenic analysis for predicting Drug-Target Pair via Machine Learning Approaches - Nature
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A Chemogenomic Toolkit to Evaluate the “Ins and Outs” of Yeast Plasma Membrane Transporters - ASM Journals
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Chemogenomic approach identified yeast YLR143W as diphthamide synthetase - pnas.org
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Utilizing yeast chemogenomic profiles for the prediction of pharmacogenomic associations in humans - Nature
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Shifting from the single to the multitarget paradigm in drug discovery - ScienceDirect.com
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A change of tactic - Nature
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A chemogenomic approach is required for effective treatment of amyotrophic lateral sclerosis - Wiley Online Library
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A Chemogenomic Screen in Saccharomyces cerevisiae Uncovers a Primary Role for the Mitochondria in Farnesol Toxicity and Its Regulation by the Pkc1 Pathway - ScienceDirect.com
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Molecular interaction fingerprint approaches for GPCR drug discovery - ScienceDirect.com
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Traditional Indigenous knowledge offers hope in global fight against a superbug - EurekAlert!
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Drug discovery in reverse - Nature
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Predicting Off-Target Binding Profiles With Confidence Using Conformal Prediction - Frontiers
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Artificial intelligence uses biggest disease database to fight cancer - theconversation.com
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Innovative Medicines Initiative - NHS Confederation
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.