Why is "Chronic granulomatous disease" trending?
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Trend Analysis
- Ranking position: #
- Date: 2026-03-29 08:03:11
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
Chronic granulomatous disease (CGD), also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome, is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds used to kill certain ingested pathogens. This leads to the formation of granulomas in many organs. CGD affects about 1 in 200,000 people in the United States, with about 20 new cases diagnosed each year.
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Search Interest Perspective
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Prime Editing for p47phox-Deficient Chronic Granulomatous Disease - NEJM
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Research Progress on Chronic Granulomatous Disease in Children - Cureus
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Beyond survival: Multisystem long-term outcomes following HSCT in chronic granulomatous disease - Rockefeller University Press
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First review of chronic granulomatous disease in Palestine: clinical and genetic characteristics - Frontiers
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Targeted gene editing and near-universal cDNA insertion of CYBA and CYBB as a treatment for chronic granulomatous disease - Nature
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Recognising Aspergillus udagawae in a child with chronic granulomatous disease - The Lancet
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First patient dosed in trial of EN-374 to treat X-linked chronic granulomatous disease - Contemporary Pediatrics
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Great Ormond Street Hospital Tackling Chronic Granulomatous Disease With Gene Therapy in Phase 1/2 Trial - CGTLive®
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Prime Editing for p47phox-Deficient Chronic Granulomatous Disease - NEJM
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World's first gene therapy for p47 Chronic Granulomatous Disease developed by UCL and GOSH - openaccessgovernment.org
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Prime to test FDA flexibility with 2-patient gene editing submission - BioPharma Dive
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First-Ever Prime-Editing Therapy Shows Safety and Efficacy in Patient With Chronic Granulomatous Disease - CRISPR Medicine News
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Prime Medicine Announces The New England Journal of Medicine Publication of PM359 Clinical Data for the Treatment of Chronic Granulomatous Disease - Yahoo Finance
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Asked and Answered: Prime Medicine CEO on First Prime Editing Patient Data - Inside Precision Medicine
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Atopy and immune dysregulation among patients with chronic granulomatous disease - Frontiers
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World’s first possible ‘cure’ of chronic granulomatous disease at Montreal’s CHU Sainte-Justine - CityNews Montreal
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Description of invasive aspergillosis in Mexican patients with chronic granulomatous disease - Rockefeller University Press
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Prime Editing Clinical Results Published for the First Time Ever - Inside Precision Medicine
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FDA clears EN-374 therapy application for X-linked chronic granulomatous disease - Contemporary Pediatrics
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Ensoma Announces $53 Million Financing to Support Key Clinical Milestones for EN-374 and Continued Development of In Vivo Hematopoietic Stem Cell Engineering Pipeline - BioSpace
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Clinical presentation, diagnosis, and treatment of chronic granulomatous disease - Frontiers
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Imaging of Chronic Granulomatous Disease in ChildrenRadioGraphics - RSNA Journals
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Liver Abscess: Think Outside the Box - Cureus
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A Fatal Case of Chronic Granulomatous Disease in a Young Man - Cureus
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Case Report: Symptomatic Chronic Granulomatous Disease in the Newborn - Frontiers
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Lentiviral gene therapy for X-linked chronic granulomatous disease - Nature
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Chronic Granulomatous Disease - NEJM
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Genetically confirmed chronic granulomatous disease in a Kenyan child: case report - Frontiers
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New gene therapy is life changing for teenage patient | UCL News - UCL - University College London
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Imaging findings of pulmonary manifestations of chronic granulomatous disease in a large single center from Shanghai, China (1999–2018) - Nature
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Gene therapy for CGD shows promising early results - Boston Children's Answers
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-deficient cell line for Chronic Granulomatous Disease gene therapy vector development - Nature
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Case report: Chronic granulomatous disease presenting with early-onset inflammatory bowel disease and normal oxidative burst testing - Frontiers
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News: The Latest Clinical Trial Updates from CRISPR Medicine News - CRISPR Medicine News
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B.C. man cured of rare disease in world-first for new gene-editing technology - Squamish Chief
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Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease - NEJM
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Updated information on chronic granulomatous disease - Contemporary Pediatrics
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Mulch pneumonitis in chronic granulomatous disease: More than just a fungal infection - Wiley Online Library
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Outcomes in hematopoetic cell transplantation in the setting of mold infections in patients with chronic granulomatous disease | Bone Marrow Transplantation - Nature
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Itraconazole to Prevent Fungal Infections in Chronic Granulomatous Disease - NEJM
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Chronic granulomatous disease and McLeod syndrome: Stem cell transplant and transfusion support in a 2-year-old patient—a case report - Frontiers
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Cytomegalovirus and Epstein-Barr Virus Co-infection in a Patient With Chronic Granulomatous Disease Co-existing With Familial Mediterranean Fever and Early-Onset Inflammatory Bowel Disease: A Case Report - Cureus
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A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease - Nature
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Prime Medicine Announces Breakthrough Clinical Data Showing - globenewswire.com
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Papulopustular Dermatitis in X-Linked Chronic Granulomatous Disease - Frontiers
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Prime Editing Shows Promise in Chronic Disease Treatment - The Clinical Trial Vanguard
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Revealing Chronic Granulomatous Disease in a Patient With Williams-Beuren Syndrome Using Whole Exome Sequencing - Frontiers
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A Case of Chronic Granulomatous Disease Masquerading As Tubercular Lymphadenitis in an Infant - Cureus
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Imaging characteristics of pulmonary BCG/TB infection in patients with chronic granulomatous disease - Nature
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A Brush with Hope: How art helped a Georgia child heal at Children’s Healthcare of Atlanta - 11Alive.com
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Bone Marrow Transplant: Evian's and Jerrick's Story - Johns Hopkins Medicine
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Successful HLA haploidentical hematopoietic SCT in chronic granulomatous disease | Bone Marrow Transplantation - Nature
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Jennifer Gori, PhD, on the Potential of a Prime Editing Approach in Treating Chronic Granulomatous Disease - CGTLive®
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Treatment of Chronic Granulomatous Disease with Nonmyeloablative Conditioning and a T-Cell–Depleted Hematopoietic Allograft - NEJM
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Defective Polymorphonuclear-Leukocyte Function and Chronic Granulomatous Disease in Two Female Children - NEJM
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A C126R de novo Mutation in CYBB Leads to X-linked Chronic Granulomatous Disease With Recurrent Pneumonia and BCGitis - Frontiers
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Iodination Defect in the Leukocytes of a Patient with Chronic Granulomatous Disease of Childhood - NEJM
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Spontaneous cystoid macula oedema in chronic granulomatous disease: a new posterior segment sign - Nature
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A Novel Mutation in Chronic Granulomatous Disease: Treating the Family, Not Just the Patient - Frontiers
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Lineage- and stage-restricted lentiviral vectors for the gene therapy of chronic granulomatous disease - Nature
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Colitis in chronic granulomatous disease - Archives of Disease in Childhood
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The first successful bone marrow transplantation in Vietnam for a young Vietnamese boy with chronic granulomatous disease: a case report - Frontiers
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Bone Marrow Transplant: Riley's Story - Johns Hopkins Medicine
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Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease - Nature
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Genetic and mutational heterogeneity of autosomal recessive chronic granulomatous disease in Tunisia - Nature
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A rare presentation of visceral leishmaniasis and epididymo-orchitis in a patient with chronic granulomatous disease - Wiley Online Library
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Chromobacterium violaceum: A rare opportunistic pathogen and clue for pediatric chronic granulomatous disease - Wiley Online Library
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Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1 PRDM16 or SETBP1 - Nature
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A Controlled Trial of Interferon Gamma to Prevent Infection in Chronic Granulomatous Disease - NEJM
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Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director - News-Medical
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PAMless Base Editors Correct X-CGD Mutation Efficiently and Precisely - Genetic Engineering and Biotechnology News
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Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous Disease - Wiley Online Library
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Candida Glabrata Lymphadenitis Following Infliximab Therapy for Inflammatory Bowel Disease in a Patient With Chronic Granulomatous Disease: Case Report and Literature Review - Frontiers
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A Novel Mutation in the NCF2 Gene in a CGD Patient With Chronic Recurrent Pneumopathy - Frontiers
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Imipenem-Resistant Nocardia cyriacigeorgica Infection in a Child with Chronic Granulomatous Disease - ASM Journals
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Association Between Discoid Lupus Erythematosus and Chronic Granulomatous Disease—Report of Two Cases and Review of the Literature - Wiley Online Library
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A world first: "prime editing" reverses effects of rare illness - nouvelles.umontreal.ca
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Genetic Variants of Chronic Granulomatous Disease: Prevalence of Deficiencies of Two Cytosolic Components of the NADPH Oxidase System - NEJM
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Mulch pneumonitis in a patient with chronic granulomatous disease - CMAJ
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Successful umbilical cord blood stem cell transplantation for chronic granulomatous disease - Nature
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Urinary Tract Disorders in Patients with Chronic Granulomatous Disease - NEJM
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Genetic Analysis of 13 Families with X-Linked Chronic Granulomatous Disease Reveals a Low Proportion of Sporadic Patients and a High Proportion of Sporadic Carriers | Pediatric Research - Nature
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The FDA Has Cleared the First Clinical Trial Application for a Prime Editor - CRISPR Medicine News
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In-utero pericardiocentesis to treat fetal hydrops caused by X-linked chronic granulomatous disease - Wiley
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Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease - Nature
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Functional and genetic characterization of two extremely rare cases of Williams–Beuren Syndrome associated with chronic granulomatous disease - Nature
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hematopoietic cells for correction of X-linked chronic granulomatous disease - Nature
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Genetic and Clinical Profiles of Disseminated Bacillus Calmette-Guérin Disease and Chronic Granulomatous Disease in China - Frontiers
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Prime gets FDA green light to begin first trial test of ‘prime editing’ - BioPharma Dive
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Absence of Cytochrome b-245 in Chronic Granulomatous Disease | NEJM - NEJM
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A Variant of Chronic Granulomatous Disease: Deficient Oxidative Metabolism Due to a Low-Affinity NADPH Oxidase - NEJM
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Reactive oxygen species–independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease - PNAS
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Phagocytosis in Chronic Granulomatous Disease and the Chediak–Higashi Syndrome - NEJM
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A novel mutation in NCF1 in an adult CGD patient with a liver abscess as first presentation | Journal of Human Genetics - Nature
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Acetaminophen use tied to false-positive test in chronic granulomatous disease: study - Medical Dialogues
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Chronic Granulomatous Disease in Females — A Deficiency of Leukocyte Glutathione Peroxidase - NEJM
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Chronic Granulomatous Disease In Children: Parents Had To Choose Which Twin Would Live - theAsianparent community
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Transplant, chemo: Family of six in last roll of dice for brave Kyran - The Mercury
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.