Why is "Desmosome" trending?

Search Interest Perspective

• Actomyosin forces trigger a conformational change in desmoplakin within desmosomes - nature.com
• The desmosomal cadherin Desmoglein-2 controls extracellular matrix expression and remodeling via NF-κB signaling in keratinocytes - Frontiers
• A Stretchy Protein Senses Forces in Cells - UC Davis
• Reduced Filaggrin Expression Reduces ERK Signaling And Disrupts Desmosomes In Atopic Eczema [c028ee] - fathomjournal.org
• Hirudin suppresses hematogenous metastasis by targeting desmosome junction transition in circulating tumor cell clusters via HIF-1α–DSG2 signaling - nature.com
• The desmosome comes into focus - Rockefeller University Press
• The Cardiac Desmosome and Arrhythmogenic Cardiomyopathies: - ahajournals.org
• The desmosome comes into focus - Rockefeller University Press
• Desmoglein-driven dynamic signaling in pemphigus vulgaris: a systematic review of pathogenic pathways - nature.com
• Pemphigus—A Disease of Desmosome Dysfunction Caused by Multiple Mechanisms - Frontiers
• Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade - ahajournals.org
• Desmosome mutations impact the tumor microenvironment to promote melanoma proliferation - nature.com
• Plakophilin 1 in cancer: context-dependent dualism, subcellular dynamics, and therapeutic targeting - Frontiers
• Genotype-Specific Outcomes of Desmosomal Cardiomyopathies | Circulation - ahajournals.org
• Desmosome mutations in keratinocytes fuel melanoma development - nature.com
• Desmosomes as Signaling Hubs in the Regulation of Cell Behavior - Frontiers
• The Desmosome-Keratin Scaffold Integrates ErbB Family and Mechanical Signaling to Polarize Epidermal Structure and Function - Frontiers
• Architecture and dynamics of a desmosome–endoplasmic reticulum complex - nature.com
• Mechanical loading of desmosomes depends on the magnitude and orientation of external stress - nature.com
• Adhesion of pancreatic tumor cell clusters by desmosomal molecules enhances early liver metastases formation - nature.com
• DPM1 modulates desmosomal adhesion and epidermal differentiation through SERPINB5 - Rockefeller University Press
• A novel Nrf2-miR-29-desmocollin-2 axis regulates desmosome function in keratinocytes - nature.com
• The molecular architecture of the desmosomal outer dense plaque by integrative structural modeling - Wiley Online Library
• Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy - Science | AAAS
• Cardiac desmosomal adhesion relies on ideal-, slip- and catch bonds - nature.com
• Protein exchange is reduced in calcium-independent epithelial junctions - Rockefeller University Press
• Cortical tension regulates desmosomal morphogenesis - Frontiers
• Advanced imaging gives researchers front row view of cellular junctions - The Pennsylvania State University
• DPM1 modulates desmosomal adhesion and epidermal differentiation through SERPINB5 | Journal of Cell Biology - Rockefeller University Press
• Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype - Science | AAAS
• Untangling Desmosomal Knots with Electron Tomography - Science | AAAS
• Increased degradation of desmosomal proteins in ACM - nature.com
• Structural basis of adhesive binding by desmocollins and desmogleins - PNAS
• Endoplasmic reticulum tethering by desmosomes - nature.com
• Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination - nature.com
• Desmosomes: new perpetrators in tumour suppression - nature.com
• Desmosomes: a role in cancer? - nature.com
• Modulation of pulmonary desmosomes by inhaler therapy in preterm-born children with bronchopulmonary dysplasia - nature.com
• From mutation to arrhythmia: Desmosomal protein breakdown as an underlying mechanism of cardiac disease - Medical Xpress
• Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris -like localisation of desmoglein-3 in human keratinocytes - nature.com
• Endocytosis of IgG, Desmoglein 1, and Plakoglobin in Pemphigus Foliaceus Patient Skin - Frontiers
• Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell–cell adhesion | Scientific Reports - nature.com
• Connexin 43 and plakophilin-2 as a protein complex that regulates blood–testis barrier dynamics - PNAS
• Overexpression of adhesion molecules and barrier molecules is associated with differential infiltration of immune cells in non-small cell lung cancer - nature.com
• Microscopic Visualization of Cell-Cell Adhesion Complexes at Micro and Nanoscale - Frontiers
• Arrhythmogenic cardiomyopathy related DSG2 mutations affect desmosomal cadherin binding kinetics - nature.com
• Unbiased screening identifies regulators of cell-cell adhesion and treatment options in pemphigus - nature.com
• Polarity signaling balances epithelial contractility and mechanical resistance - nature.com
• The molecular architecture of cadherins in native epidermal desmosomes - nature.com
• A role for caveolin-1 in desmoglein binding and desmosome dynamics - Oncogene - nature.com
• Loss of the desmosomal cadherin desmoglein-2 suppresses colon cancer cell proliferation through EGFR signaling - nature.com
• Are desmosomes more than tethers for intermediate filaments? - nature.com
• Decoding Signaling Pathways that Lead to Scar Tissue - Northwestern University
• FAM83H and casein kinase I regulate the organization of the keratin cytoskeleton and formation of desmosomes - nature.com
• Genotype-phenotype relationship in patients with arrhythmogenic right ventricular cardiomyopathy caused by desmosomal gene mutations: A systematic review and meta-analysis - nature.com
• Cells on the Move - Furman University
• PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus - nature.com
• Targeting desmosomal adhesion and signalling for intestinal barrier stabilization in inflammatory bowel diseases—Lessons from experimental models and patients - Wiley Online Library
• Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype - Science | AAAS
• Advanced imaging gives researchers front row view of cellular junctions - Penn State Health News
• Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus - Frontiers
• Intermediate cells of in vitro cellular reprogramming and in vivo tissue regeneration require desmoplakin - Science | AAAS
• GSK3- and PRMT-1–dependent modifications of desmoplakin control desmoplakin–cytoskeleton dynamics - Rockefeller University Press
• Desmoglein-2 as a cancer modulator: friend or foe? - Frontiers
• Desmoglein 2 regulates cardiogenesis by restricting hematopoiesis in the developing murine heart - nature.com
• Intracellular Desmoglein-2 cleavage sensitizes epithelial cells to apoptosis in response to pro-inflammatory cytokines - nature.com
• Working out the strength and flexibility of desmosomes - nature.com
• Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase - nature.com
• A novel DSP zebrafish model reveals training- and drug-induced modulation of arrhythmogenic cardiomyopathy phenotypes - nature.com
• Desmosomal adhesion regulates epithelial morphogenesis and cell positioning - nature.com
• Overview of junctional complexes during mammalian early embryonic development - Frontiers
• Evaluation of autoantibodies to desmoglein-2 in dogs with and without cardiac disease - nature.com
• Desmoplakin CSM models unravel mechanisms regulating the binding to intermediate filaments and putative therapeutics for cardiocutaneous diseases - nature.com
• Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy - nature.com
• New mutation in the desmoplakin gene leads to arrhythmogenic cardiomyopathy - Medical Xpress
• Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis - nature.com
• Apremilast prevents blistering in human epidermis and stabilizes keratinocyte adhesion in pemphigus - nature.com
• The p.A897KfsX4 frameshift variation in desmocollin-2 is not a causative mutation in arrhythmogenic right ventricular cardiomyopathy - nature.com
• Uncovering cellular mechanisms driving epidermal form and function - Phys.org
• Desmosomes: Structure and Function in Normal and Diseased Epidermis - Wiley Online Library
• Predicted Risk of Ventricular Arrhythmias in a Genome-First Population With Genetic Risk for Arrhythmogenic Right Ventricular Cardiomyopathy - ahajournals.org
• Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases - Frontiers
• Desmocollin switching in colorectal cancer - nature.com
• Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy - nature.com
• Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy - debuglies.com
• A new fold on an old story: attachment of intermediate filaments to desmosomes - nature.com
• Damaged Keratin Filament Network Caused by KRT5 Mutations in Localized Recessive Epidermolysis Bullosa Simplex - Frontiers
• Cadherins: cellular adhesive molecules serving as signalling mediators - Wiley
• Desmosome and hemidesmosome - doccheck.com
• Titin and desmosomal genes in the natural history of arrhythmogenic right ventricular cardiomyopathy (Contributed by Drs. Francesca Brun and Luisa Mestroni for the authors) - BMJ Blogs
• Desmosomes and gap junctions (nexus) - doccheck.com
• How skin cells protect themselves against stress - Universität Münster