Why is "Eicosanoid" trending?
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Trend Analysis
- Ranking position: #
- Date: 2026-03-25 13:47:11
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
Eicosanoids are signaling molecules made by the enzymatic or non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids (PUFAs) that are, similar to arachidonic acid, around 20 carbon units in length. Eicosanoids are a sub-category of oxylipins, i.e. oxidized fatty acids of diverse carbon units in length, and are distinguished from other oxylipins by their overwhelming importance as cell signaling molecules. Eicosanoids function in diverse physiological systems and pathological processes such as: mounting or inhibiting inflammation, allergy, fever and other immune responses; regulating the abortion of pregnancy and normal childbirth; contributing to the perception of pain; regulating cell growth; controlling blood pressure; and modulating the regional flow of blood to tissues. In performing these roles, eicosanoids most often act as autocrine signaling agents to impact their cells of origin or as paracrine signaling agents to impact cells in the proximity of their cells of origin. Some eicosanoids, such as prostaglandins, may also have endocrine roles as hormones to influence the function of distant cells.
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Search Interest Perspective
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Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho-Epithelial Cells by Modulating Eicosanoid Lipid Signaling - Wiley
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Eicosanoid and eicosanoid-related inflammatory mediators and exercise intolerance in heart failure with preserved ejection fraction - Nature
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Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart | Circulation Research - American Heart Association Journals
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Eicosanoids in Cancer: New Roles in Immunoregulation - Frontiers
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Dupilumab Initiation for Surgically Refractory Chronic Rhinosinusitis With Nasal Polyps Is Associated With Differential Expression of CLC and Activation of Eicosanoid Pathways - Wiley Online Library
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Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression - PNAS
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A genome-wide association study identifies 41 loci associated with eicosanoid levels | Communications Biology - Nature
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“A Time to Tear Down and a Time to Mend”: The Role of Eicosanoids in Atherosclerosis - American Heart Association Journals
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Eicosanoid Control Over Antigen Presenting Cells in Asthma - Frontiers
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Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19 - Nature
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Eicosanoid Biosynthesis in Male Reproductive Development: Effects of Perinatal Exposure to NSAIDs and Analgesic Drugs - Frontiers
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CYP eicosanoid pathway mediates colon cancer‐promoting effects of dietary linoleic acid - Wiley
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Eicosanoid storm in infection and inflammation - Nature
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Eicosanoids in inflammation in the blood and the vessel - Frontiers
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Comprehensive high-resolution multiple-reaction monitoring mass spectrometry for targeted eicosanoid assays - Nature
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The Role(s) of Eicosanoids and Exosomes in Human Parturition - Frontiers
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Integrated plasma metabolomics and lipidomics profiling highlight distinctive signatures with hashimoto’s thyroiditis - Nature
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Prediction and associations of preterm birth and its subtypes with eicosanoid enzymatic pathways and inflammatory markers - Nature
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Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages - Nature
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MicroRNA Involved in Inflammation: Control of Eicosanoid Pathway - Frontiers
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Editorial: Eicosanoids and cytokines: Resolution of inflammation - Frontiers
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The association between eicosanoids and incident atrial fibrillation in the Framingham Heart Study - Nature
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Oates lands lifetime achievement award from Eicosanoid foundation - VUMC News
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Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer - Nature
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Nasal Polyp Severity and Eicosanoid Levels in Chronic Rhinosinusitis - Pulmonology Advisor
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Pleiotropic Functions of Cytochrome P450 Monooxygenase-Derived Eicosanoids in Cancer - Frontiers
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Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury - ScienceDirect.com
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ASM Career Development Grant for Postdoctoral Women Recipient Plans to Learn Eicosanoid Mass Spectrometry - American Society for Microbiology
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Editorial: Eicosanoids in Cancer - Frontiers
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Eicosanoid Metabolomic Profile of Remdesivir Treatment in Rat Plasma by High-Performance Liquid Chromatography Mass Spectrometry - Frontiers
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Omega-3 fatty acids cause dramatic changes in TLR4 and purinergic eicosanoid signaling - PNAS
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Eicosanoid-Regulated Myeloid ENaC and Isolevuglandin Formation in Human Salt-Sensitive Hypertension - American Heart Association Journals
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Tear eicosanoids in healthy people and ocular surface disease - Nature
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Phospholipase Cγ2 regulates endocannabinoid and eicosanoid networks in innate immune cells - PNAS
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The Role of Eicosanoids in Gynecological Malignancies - Frontiers
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Monitoring urinary eicosanoids a noninvasive approach for molecular phenotyping of asthma - Healio
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The role of eicosanoids in experimental Lyme arthritis - Frontiers
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Lipids in Liver Failure Syndromes: A Focus on Eicosanoids, Specialized Pro-Resolving Lipid Mediators and Lysophospholipids - Frontiers
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Inflammatory Eicosanoids Increase Amyloid Precursor Protein Expression via Activation of Multiple Neuronal Receptors - Nature
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Serum Eicosanoids Metabolomics Profile in a Mouse Model of Renal Cell Carcinoma: Predicting the Antitumor Efficacy of Anlotinib - Frontiers
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Prostaglandins and Other Eicosanoids in Insects: Biosynthesis and Biological Actions - Frontiers
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Elevated Levels of Anti-Inflammatory Eicosanoids and Monocyte Heterogeneity in Mycobacterium tuberculosis Infection and Disease - Frontiers
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Prostaglandins and Their Receptors in Insect Biology - Frontiers
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Novel eicosanoids from the COX-2 reaction: 5-hydroxy-prostaglandins - American Society for Biochemistry and Molecular Biology
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Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids - Nature
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Candida albicans and Pseudomonas aeruginosa Interaction, with Focus on the Role of Eicosanoids - Frontiers
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Spinal Reflex Control of Arterial Blood Pressure: The Role of TRP Channels and Their Endogenous Eicosanoid Modulators - Frontiers
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Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid - Nature
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Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions - Wiley
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Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways - PNAS
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The Effects of Omega-3 Fatty Acid Supplementation in Pregnancy on Maternal Eicosanoid, Cytokine, and Chemokine Secretion - Nature
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Clinical and Experimental Hepatology - Termedia
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Dorsal switch protein 1 as a damage signal in insect gut immunity to activate dual oxidase via an eicosanoid, PGE2 - Frontiers
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Epoxyeicosanoids promote organ and tissue regeneration - PNAS
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Inflammasome activity regulation by PUFA metabolites - Frontiers
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Roundworm Study May Lead to New Therapies for Allergies and Asthma - Genetic Engineering and Biotechnology News
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The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis - Nature
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Unsaturated lipid bodies as a hallmark of inflammation studied by Raman 2D and 3D microscopy - Nature
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Quantitation of Omega Fatty Acids by HPLC and Charged Aerosol Detection - Chromatography Online
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Breast Milk Fatty Acids, Eicosanoids, and Cytokines in Mothers with and without Allergic Disease - Nature
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UCD Professor Awarded for Research Development of Aspirin, Advil, Ibuprofin and Motrin - Patch
Why This Topic Is Trending
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Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.