Why is "Enteric nervous system" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-22 13:28:33
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
The enteric nervous system (ENS) is one of the three divisions of the autonomic nervous system (ANS), the others being the sympathetic nervous system (SNS) and parasympathetic nervous system (PSNS). The ENS is formed from the myenteric plexus, and the submucosal plexus, and consists of a mesh-like system of neurons that governs the functions of the gastrointestinal tract, including motility and secretion, and is known as the "second brain". It is derived from neural crest cells.
Read more on Wikipedia →Related Topics
- Myenteric plexus
- Submucosal plexus
- Peristalsis
- Segmentation contractions
- APUD cell
- Abdominopelvic cavity
- Accessory digestive gland
- Acetylcholine
- Affective neuroscience
- Afferent nerve fiber
Trending Topic Today
Search Interest Perspective
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UMass Chan researchers shed light on how inflammation in GI tract rewires enteric nervous system - UMass Chan Medical School
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enGLOW 3D microscopy of the enteric nervous system in cleared human and mouse gut | Communications Biology - Nature
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Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation - Science | AAAS
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Interoception: The enteric nervous system enters the chat - ScienceDirect.com
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Enteric nervous system in microbiota-associated gut inflammation - Frontiers
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Into the belly of the brainstem: The neurons of the “extended” enteric nervous system - PNAS
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The Enteric Nervous System as a Mediator of Microbiota-Gut-Brain Interactions in Parkinson's Disease - Wiley Online Library
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stem cells toward the secretory lineage impeding type 2 immune programs - Nature
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Editorial: Exploring gut neuroimmunology: focus on the enteric nervous system in health and disease - Frontiers
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Long-chain unsaturated free fatty acids control gut motility via nitrergic ganglia of the enteric nervous system - PNAS
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Stereoscopic Quantitative Analysis of Enteric Nervous System in Patients With Slow Transit Constipation - Wiley Online Library
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Disease-specific alterations of the enteric nervous system in precancerous colonic mucosa and their implications for mucin regulation - Nature
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Microbiota and enteric nervous system crosstalk in diabetic gastroenteropathy: bridging mechanistic insights to microbiome-based therapies - Frontiers
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Immune cell profiling reveals diverse niches of immune residents of the enteric nervous system and potential neuroimmune interactions - PNAS
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The role of the enteric nervous system in the pathogenesis of Clostridioides difficile infection - Nature
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Sox11 genes affect neuronal differentiation in the developing zebrafish enteric nervous system - PNAS
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An exploratory in vitro co-culture of enteric neurons and smooth muscle cells demonstrates neuronal contribution to muscle layer formation | Scientific Reports - Nature
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Nutrients activate distinct patterns of small-intestinal enteric neurons - Nature
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Research Spotlight: Mapping How Gut Neurons Respond to Bacteria, Parasites and Food Allergy - Mass General Brigham
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Gut neurons help body fight inflammation with immune-regulating molecule - Medical Xpress
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Imaging the enteric nervous system - Frontiers
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Anatomical and functional maturation of the mid-gestation human enteric nervous system - Nature
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Gut and mind – how they are connected - Karolinska Institutet
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Dedicated macrophages organize and maintain the enteric nervous system - Nature
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Disorders of the enteric nervous system — a holistic view - Nature
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Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility - Nature
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Aqueous extract of Solanum americanum Mill. relieves functional constipation by modulating the enteric nervous system and gut micro-ecosystems - Frontiers
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Advances in Enteric Neurobiology: The “Brain” in the Gut in Health and Disease - Journal of Neuroscience
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Neonatal antibiotics have long term sex‐dependent effects on the enteric nervous system - Wiley
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Lineage-dependent spatial and functional organization of the mammalian enteric nervous system - Science | AAAS
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Gut Neurons Found To Regulate Immune Response in IBD - Technology Networks
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Enteric nervous system development: what could possibly go wrong? - Nature
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Gut macrophages shape and sustain the enteric nervous system - Nature
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Visualizing enteric nervous system activity through dye-free dynamic full-field optical coherence tomography - Nature
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Region-specific remodeling of the enteric nervous system and enteroendocrine cells in the colon of spinal cord injury patients - Nature
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Enteric nervous system regeneration and functional cure of experimental digestive Chagas disease with trypanocidal chemotherapy - Nature
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Preconception maternal gut dysbiosis affects enteric nervous system development and disease susceptibility in offspring via the GPR41–GDNF/RET/SOX10 signaling pathway - Wiley Online Library
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Early life interaction between the microbiota and the enteric nervous system - American Physiological Society Journal
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Enteric Nervous System: The Bridge Between the Gut Microbiota and Neurological Disorders - Frontiers
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Regulation of enteric nervous system via sacral nerve stimulation in opioid-induced constipated rats - Frontiers
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Automated computational analysis reveals structural changes in the enteric nervous system of nNOS deficient mice - Nature
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Guardians of the gut: influence of the enteric nervous system on the intestinal epithelial barrier - Frontiers
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Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice - Nature
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Intestinal distension orchestrates neuronal activity in the enteric nervous system of adult mice - Wiley
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Gut Neurons Direct Immune Healing After Inflammation - Neuroscience News
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Zebrafish: A Model Organism for Studying Enteric Nervous System Development and Disease - Frontiers
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Identification of a Rhythmic Firing Pattern in the Enteric Nervous System That Generates Rhythmic Electrical Activity in Smooth Muscle - Journal of Neuroscience
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Not just a gut feeling: nervous system in the gut recognises sugars, fats and proteins - KU Leuven
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The enteric nervous system deficits in autism spectrum disorder - Frontiers
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Understanding the ‘second brain’ in your gut - The World Economic Forum
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Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks - PNAS
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Enteric nervous system α-synuclein immunoreactivity in idiopathic REM sleep behavior disorder - Neurology® Journals
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Analysis of enteric nervous system and intestinal epithelial barrier to predict complications in Hirschsprung’s disease - Nature
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Simultaneous optical and electrical in vivo analysis of the enteric nervous system - Nature
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ELP1, the Gene Mutated in Familial Dysautonomia, Is Required for Normal Enteric Nervous System Development and Maintenance and for Gut Epithelium Homeostasis - Journal of Neuroscience
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Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system - Nature
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A Bird's Eye View of Enteric Nervous System Development: Lessons From the Avian Embryo - Nature
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Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies - Nature
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Role of 5-HT in the enteric nervous system and enteroendocrine cells - British Pharmacological Society | Journals
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Immunohistochemical and ultrastructural analysis of the maturing larval zebrafish enteric nervous system reveals the formation of a neuropil pattern - Nature
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Systemic gene delivery transduces the enteric nervous system of guinea pigs and cynomolgus macaques - Nature
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Enteric Nervous System Regulation of Intestinal Stem Cell Differentiation and Epithelial Monolayer Function - Nature
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3D Synthetic Peptide-based Architectures for the Engineering of the Enteric Nervous System - Nature
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Vasculature in the mouse colon and spatial relationships with the enteric nervous system, glia, and immune cells - Frontiers
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Role of 5-HT in the enteric nervous system and enteroendocrine cells - British Pharmacological Society | Journals
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Is the enteric nervous system a lost piece of the gut-kidney axis puzzle linked to chronic kidney disease? - ScienceDirect.com
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Label-free, fast, 2-photon volume imaging of the organization of neurons and glia in the enteric nervous system - Frontiers
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Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon - Nature
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Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System - Journal of Neuroscience
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ELP1, the Gene Mutated in Familial Dysautonomia, Is Required for Normal Enteric Nervous System Development and Maintenance and for Gut Epithelium Homeostasis - Journal of Neuroscience
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Plp1 in the enteric nervous system is preferentially expressed during early postnatal development in mouse as DM20, whose expression appears reliant on an intronic enhancer - Frontiers
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Comparative transcriptomics reveals highly conserved regional programs between porcine and human colonic enteric nervous system - Nature
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Ret deficiency decreases neural crest progenitor proliferation and restricts fate potential during enteric nervous system development - PNAS
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Crosstalk between omega-6 oxylipins and the enteric nervous system: Implications for gut disorders? - Frontiers
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Improving 3D imaging of the enteric nervous system - Nature
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In the Gut’s ‘Second Brain,’ Key Agents of Health Emerge - Quanta Magazine
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HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system - Nature
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Genetic background-dependent abnormalities of the enteric nervous system and intestinal function in Kif26a-deficient mice - Nature
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The Gut and the Brain - Harvard Medical School
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Impact of Intestinal Peptides on the Enteric Nervous System: Novel Approaches to Control Glucose Metabolism and Food Intake - Frontiers
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Endothelin-3 stimulates cell adhesion and cooperates with β1-integrins during enteric nervous system ontogenesis - Nature
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Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System - Journal of Neuroscience
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A new study characterizes the cellular topology and diversity of the enteric nervous system in mice and humans using novel methodologies - Gut Microbiota for Health
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Cellular prion protein is expressed in the human enteric nervous system - Nature
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Hepatocyte Growth Factor and MET Support Mouse Enteric Nervous System Development, the Peristaltic Response, and Intestinal Epithelial Proliferation in Response to Injury - Journal of Neuroscience
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Two independent networks of interstitial cells of Cajal work cooperatively with the enteric nervous system to create colonic motor patterns - Frontiers
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Mapping the “brain in the gut” may provide clues to gastrointestinal disorders - Karolinska Institutet
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Enteric neuroimmune interactions coordinate intestinal responses in health and disease - Nature
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Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility - Nature
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How big is the little brain in the gut? Neuronal numbers in the enteric nervous system of mice, Guinea pig, and human - Wiley Online Library
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Gut microbiota modulates function and anatomy of the enteric nervous system through serotonin signaling in adult mice - Gut Microbiota for Health
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Researchers Discover Death and Rebirth of the Gut Brain - Johns Hopkins Medicine
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Hepatocyte Growth Factor and MET Support Mouse Enteric Nervous System Development, the Peristaltic Response, and Intestinal Epithelial Proliferation in Response to Injury - Journal of Neuroscience
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Think Twice: How the Gut's "Second Brain" Influences Mood and Well-Being - Scientific American
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The Gut and Parkinson's Disease—A Bidirectional Pathway - Frontiers
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New way for gut neurons to communicate with the brain - Medical News Today
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Aggregation of alpha-synuclein in enteric neurons does not impact function in vitro - Nature
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Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction - JCI.org
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A functional network of highly pure enteric neurons in a dish - Frontiers
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Opioid receptors may guide formation of gut nervous system in zebrafish - The Transmitter
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.