Why is "FGF1" trending?
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Trend Analysis
- Ranking position: #
- Date: 2026-04-01 15:10:11
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene. It is synthesized as a 155 amino acid polypeptide, whose mature form is a non-glycosylated 17-18 kDa protein. Fibroblast growth factor protein was first purified in 1975, but soon afterwards others using different conditions isolated acidic FGF, Heparin-binding growth factor-1, and Endothelial cell growth factor-1. Gene sequencing revealed that this group was actually the same growth factor and that FGF1 was a member of a family of FGF proteins.
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Trending Topic Today
Search Interest Perspective
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FGF1-FGFR2 axis regulated by nuclear receptor RORγ represents an effective strategy in intrahepatic cholangiocarcinoma - Nature
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UC & University Hospital Are First in the U.S. to Use New Growth Factor Protein - University of Cincinnati
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Sodium new houttuyfonate affects tumor angiogenesis by suppressing FGF1 expression and the p38/MAPK signaling pathway in pancreatic cancer - Nature
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Autocrine FGF1 signaling promotes glucose uptake in adipocytes - PNAS
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FGF-1 improves blood flow, motor function in Parkinson’s patient - Parkinson's News Today
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Prefrontal FGF1 Signaling is Required for Accumbal Deep Brain Stimulation Treatment of Addiction - Wiley
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Salk researchers find a new route for regulating blood sugar levels independent of insulin - Salk Institute for Biological Studies
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Synthesis of Novel Suramin Analogs With Anti-Proliferative Activity via FGF1 and FGFRD2 Blockade - Frontiers
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CircZBTB46 alleviates metabolic dysfunction–associated steatotic liver disease by targeting miRNA-326/FGF1 axis - Nature
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Colonic epithelial-derived FGF1 drives intestinal stem cell commitment toward goblet cells to suppress inflammatory bowel disease - Nature
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FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis - Nature
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Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice - Nature
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FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization - Nature
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The EGFR-STYK1-FGF1 axis sustains functional drug tolerance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer - Nature
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FGF1 stops diabetes in its tracks - Nature
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Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer - Nature
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FGF1 C-terminal domain and phosphorylation regulate intracrine FGF1 signaling for its neurotrophic and anti-apoptotic activities - Nature
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Characterization of FN1–FGFR1 and novel FN1–FGF1 fusion genes in a large series of phosphaturic mesenchymal tumors - Nature
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A PPARγ–FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis - Nature
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Catheter-based Intramyocardial Injection of FGF1 or NRG1-loaded MPs Improves Cardiac Function in a Preclinical Model of Ischemia-Reperfusion - Nature
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ameliorates chronic kidney disease via PI3K/AKT mediated suppression of oxidative stress and inflammation - Nature
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LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis - Nature
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FGF1 goes long to tackle diabetes - Nature
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FGF1 signalling cascade suppresses lipolysis - Nature
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FGF1 ameliorates obesity-associated hepatic steatosis by reversing IGFBP2 hypermethylation - Wiley
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Fibroblast Growth Factor-1 Activates Neurons in the Arcuate Nucleus and Dorsal Vagal Complex - Frontiers
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Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission - Nature
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Compassionate Use Clinical Trial of FGF-1 Initiated for Amyotrophic Lateral Sclerosis - NeurologyLive
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FGF-1 Safely Easing Parkinson’s Symptoms in Early Trial, Zhittya Reports - Parkinson's News Today
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Fibroblast Growth Factor-1 Improves Insulin Resistance via Repression of JNK-Mediated Inflammation - Frontiers
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Author Correction: Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice - Nature
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FGF1 restores blood glucose levels and insulin sensitivity in diabetic mice - Nature
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Roles of FGFs as Adipokines in Adipose Tissue Development, Remodeling, and Metabolism - Frontiers
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Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects - Nature
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BRAF inhibition causes resilience of melanoma cell lines by inducing the secretion of FGF1 - Nature
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One injection stops diabetes in its tracks - Salk Institute for Biological Studies
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FGF1 protects neuroblastoma SH-SY5Y cells from p53-dependent apoptosis through an intracrine pathway regulated by FGF1 phosphorylation - Nature
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Fibroblast Growth Factor 1 Regulates Blood Glucose by Inhibiting Fat Breakdown - Inside Precision Medicine
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Cell surface localization of importin α1/KPNA2 affects cancer cell proliferation by regulating FGF1 signalling - Nature
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Pilot Trial of FGF-1 to Promote Blood Vessel Growth in Brain Planned - Parkinson's News Today
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Structural interactions of fibroblast growth factor receptor with its ligands - PNAS
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Fibroblast Growth Factor 1 Promotes Rat Stem Leydig Cell Development - Frontiers
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Antibody-induced dimerization of FGFR1 promotes receptor endocytosis independently of its kinase activity - Nature
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TAK1 interacts with FGFR3. - PLOS
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From feast to famine: A metabolic switch that may help diabetes treatment - Salk Institute for Biological Studies
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FGF1 protects FGFR1-overexpressing cancer cells against drugs targeting tubulin polymerization by activating AKT via two independent mechanisms - Frontiers
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Salk Professor Ronald Evans awarded $1.2 million by Larry L. Hillblom Foundation to study a new druggable pathway that could help treat diabetes - Salk Institute for Biological Studies
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Mechanism of FGF receptor dimerization and activation - Nature
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Persistence of Fear Memory Depends on a Delayed Elevation of BAF53b and FGF1 Expression in the Lateral Amygdala - Journal of Neuroscience
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Fibroblast Growth Factors 1, 2, 17, and 19 Are the Predominant FGF Ligands Expressed in Human Fetal Growth Plate Cartilage - Nature
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Stimulating Blood Vessel Growth Using FGF1 May Hold Promise for PD, Company Says - Parkinson's News Today
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Association of positional and functional candidate genes FGF1 FBN2 , and LOX on 5q31 with intracranial aneurysm - Nature
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FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels - PNAS
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BPS Publications - British Pharmacological Society | Journals
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Genetic factors influencing ALS survival identified in Japanese study - ALS News Today
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Zhittya Genesis Medicine Announces: Landmark fMRI Study - GlobeNewswire
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Fibroblast Growth Factor Signaling in Metabolic Regulation - Frontiers
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Trefoil Therapeutics' drug boosts post-cataract surgery recovery - drugdiscoverytrends.com
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Regulation of proliferation-survival decisions is controlled by FGF1 secretion in retinal pigmented epithelial cells - Nature
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A Single Injection Can Eliminate Type 2 Diabetes in Mice For Months - ScienceAlert
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Zhittya Genesis Medicine Announces: Landmark fMRI Study Reveals 21.2% Boost in Brain Blood Flow in Parkinson’s Patient Following Six Months of Intranasal FGF-1 Therapy - Yahoo Finance
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The optimized priming effect of FGF-1 and FGF-2 enhances preadipocyte lineage commitment in human adipose-derived mesenchymal stem cells - Wiley Online Library
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.