Why is "Gamma-glutamyltransferase" trending?
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- Date: 2026-03-30 16:47:15
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Wikipedia Overview
Gamma-glutamyltransferase is a transferase that catalyzes the transfer of gamma-glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water. GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione as well as drug and xenobiotic detoxification. Other lines of evidence indicate that GGT can also exert a pro-oxidant role, with regulatory effects at various levels in cellular signal transduction and cellular pathophysiology. This transferase is found in many tissues, the most notable one being the liver, and has significance in medicine as a diagnostic marker.
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Modulation of peroxisome proliferator activated receptor genes and gamma glutamyl transferase in rats by high intensity interval training and livergol - Nature
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Isolated Gamma-Glutamyl Transferase Elevation in an Asymptomatic Adolescent: An Unusual Presentation of Focal Nodular Hyperplasia - Cureus
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Clinical and Genetic Spectra of Progressive Familial Intrahepatic Cholestasis With Normal GGT: 31 Pediatric Patients and 16 Novel Variants - Wiley Online Library
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A cross sectional study of the diabetes mediated GGT to HDL ratio and cognitive function in older adults - Nature
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Prognostic Value of Gamma-Glutamyltransferase in Male Patients With Idiopathic Pulmonary Arterial Hypertension - Frontiers
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Serum levels of gamma-glutamyltransferase predict outcome in heart failure with preserved ejection fraction - Nature
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Gamma glutamyltransferase and risk of dementia in prediabetes and diabetes - Nature
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Association between the accumulation of elevated serum γ-glutamyltransferase level and risk of atrial fibrillation: a nationwide cohort study - Nature
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Serum gamma-glutamyltransferase activity and Parkinson’s disease risk in men and women - Nature
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Gamma-glutamyl transferase and risk of all-cause and disease-specific mortality: a nationwide cohort study - Nature
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Association of gamma-glutamyl transferase variability with risk of venous thrombosis - Nature
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Association between plasma gamma-glutamyltransferase fractions and metabolic syndrome among hypertensive patients | Scientific Reports - Nature
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Pretherapeutic gamma-glutamyltransferase is an independent prognostic factor for patients with renal cell carcinoma - Nature
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Higher gamma-glutamyl transferase levels are associated with an increased risk of incident systemic sclerosis: a nationwide population-based study | Scientific Reports - Nature
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The different associations of serum gamma-glutamyl transferase and alanine aminotransferase with insulin secretion, β-cell function, and insulin resistance in non-obese Japanese - Nature
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Considering serum alanine aminotransferase and gamma-glutamyltransferase levels together strengthen the prediction of impaired fasting glucose risk: a cross-sectional and longitudinal study - Nature
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Gamma-glutamyl transferase and calculus of kidney incidence: a Mendelian randomization study - Nature
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Gamma-glutamyltransferase as novel biomarker in patients with uterine leiomyosarcoma - Nature
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Association of gamma-glutamyl transferase with subclinical coronary atherosclerosis and cardiac outcomes in non-alcoholics - Nature
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Association between Serum Gamma-glutamyl transferase and Intracranial Arterial Calcification in Acute Ischemic Stroke Subjects - Nature
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Gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio has a non-linear association with non-alcoholic fatty liver disease: A secondary prospective cohort study in non-obese Chinese adults - Frontiers
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Prognostic value of long-term gamma-glutamyl transferase variability in individuals with diabetes: a nationwide population-based study - Nature
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Gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio is a more powerful marker than TyG index for predicting metabolic syndrome in patients with type 2 diabetes mellitus - Frontiers
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Increased risk of ischemic stroke associated with elevated gamma-glutamyl transferase level in adult cancer survivors: a population-based cohort study - Nature
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γ-Glutamyltransferase enzyme activity of cancer cells modulates L-γ-glutamyl-p-nitroanilide (GPNA) cytotoxicity - Nature
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Gamma-glutamyl transferase variability can predict the development of end-stage of renal disease: a nationwide population-based study - Nature
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Elevated gamma-glutamyl transpeptidase level is associated with an increased risk of hip fracture in postmenopausal women - Nature
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Study of Serum Gamma-Glutamyl Transferase Levels in Patients With Acute Ischemic Stroke - Cureus
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Association between serum γ-glutamyl transferase and advanced colorectal adenoma among inpatients: a case-control study - Frontiers
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Serum Gamma-Glutamyltransferase Levels are Associated with Cardiovascular Risk Factors in China: A Nationwide Population-Based Study - Nature
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The Association Between Serum Gamma-Glutamyl Transferase and Gastrointestinal Cancer Risk: A Systematic Review and Meta-Analysis - Wiley Online Library
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Prognostic significance of preoperative gamma-glutamyltransferase to lymphocyte ratio index in nonfunctional pancreatic neuroendocrine tumors after curative resection - Nature
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Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure–Function Relationship and Its Biotechnological Applications - Frontiers
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Elevated GGT to HDL ratio as a marker for the risk of NAFLD and liver fibrosis - Nature
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Serum gamma-glutamyl transferase, a marker of alcohol intake, is associated with telomere length and cardiometabolic risk in young adulthood - Nature
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Gamma-glutamyltransferase 7 suppresses gastric cancer by cooperating with RAB7 to induce mitophagy - Nature
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Association Between Sex-Specific Serum Gamma-Glutamyltransferase and Incidence of Hypertension in a Chinese Population Without Metabolic Syndrome: A Prospective Observational Study - Frontiers
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γ‐Glutamyl Transferase and Long‐Term Survival in the SYNTAXES Trial: Is It Just the Liver? - American Heart Association Journals
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Association of hyperuricemia and gamma glutamyl transferase as a marker of metabolic risk in alcohol use disorder - Nature
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Redox Mechanisms in Cisplatin Resistance of Cancer Cells: The Twofold Role of Gamma-Glutamyltransferase 1 (GGT1) - Frontiers
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Expression Status and Prognostic Significance of Gamma-Glutamyl Transpeptidase Family Genes in Hepatocellular Carcinoma - Frontiers
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Rapid detection of metastatic lymph nodes of colorectal cancer with a gamma-glutamyl transpeptidase-activatable fluorescence probe - Nature
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Prognostic Value of Gamma-Glutamyl Transpeptidase to Lymphocyte Count Ratio in Patients With Single Tumor Size ≤ 5 cm Hepatocellular Carcinoma After Radical Resection - Frontiers
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Evaluation of Homocysteine and Gamma-Glutamyl Transferase Concentrations As Markers of Chronic Kidney Disease: An Indian Perspective - Cureus
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Elevated Preoperative Serum Gamma-glutamyltranspeptidase Predicts Poor Prognosis for Hepatocellular Carcinoma after Liver Transplantation - Nature
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A Case of Cholestatic Liver Involvement Secondary to Amyloid Light Chain Amyloidosis With New-Onset Hypercholesterolemia and Elevated Gamma-Glutamyltransferase Level - Cureus
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Gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio: A valuable predictor of type 2 diabetes mellitus incidence - Frontiers
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Association of gamma-glutamyltransferase with severity of disease at diagnosis and prognosis of ovarian cancer - Nature
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Liver Enzymes in Early to Mid-pregnancy, Insulin Resistance, and Gestational Diabetes Risk: A Longitudinal Analysis - Frontiers
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Higher gamma-glutamyl transferase levels predict greater systemic sclerosis risk - Healio
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Sex difference in the associations among liver function parameters with incident diabetes mellitus in a large Taiwanese population follow-up study - Frontiers
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γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis - Nature
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Improved prediction of 10-year risk of severe liver disease in the general population using commonly available biomarkers - Wiley Online Library
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Gamma-Glutamyl Transferase Combined With Conventional Ultrasound Features in Diagnosing Biliary Atresia - Wiley Online Library
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Glutathione levels modulation as a strategy in host-parasite interactions—insights for biology of cancer - Frontiers
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Relationship between traditional risk factors for hypertension and systolic blood pressure in the Tohoku Medical Megabank Community-based Cohort Study - Nature
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Intraoperative imaging of hepatic cancers using γ-glutamyltranspeptidase-specific fluorophore enabling real-time identification and estimation of recurrence - Nature
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Gamma-glutamyl cycle in plants: a bridge connecting the environment to the plant cell? - Frontiers
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Prognostic potential of standard laboratory parameters in patients with metastatic renal cell cancer receiving first-line immunotherapy - Nature
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New pediatric percentiles of liver enzyme serum levels (alanine aminotransferase, aspartate aminotransferase, γ-glutamyltransferase): Effects of age, sex, body mass index, and pubertal stage - Wiley Online Library
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γ -Glutamyl transpeptidase-activable nanoprobe crosses the blood-brain barrier for immuno-sonodynamic therapy of glioma - Nature
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Gut microbiome is associated with metabolic syndrome accompanied by elevated gamma-glutamyl transpeptidase in men - Frontiers
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The association of liver enzymes with diabetes mellitus risk in different obesity subgroups: A population-based study - Frontiers
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The Mystery of Episodic Recurrent Jaundice in a Young Male: Cholestasis With a Normal Gamma-Glutamyl Transferase - Cureus
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Association between liver function and metabolic syndrome in Chinese men and women - Nature
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Von-Meyenburg Complex: A Case of Elevated Gamma-GT - Cureus
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Hepatobiliary phenotype of individuals with chronic intestinal disorders - Scientific Reports - Nature
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Diagnostic value of the γ-glutamyltransferase and alanine transaminase ratio, alpha-fetoprotein, and protein induced by vitamin K absence or antagonist II in hepatitis B virus-related hepatocellular carcinoma - Nature
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The longitudinal effect of the aldehyde dehydrogenase 2*2 allele on the risk for nonalcoholic fatty liver disease - Nature
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Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes - Nature
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Helicobacter pylori γ-glutamyl transferase contributes to colonization and differential recruitment of T cells during persistence - Nature
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GGT level proves a strong risk factor for cardiovascular disease - healthcare-in-europe.com
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The effect of liver enzymes on adiposity: a Mendelian randomization study - Nature
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Immune Checkpoint Inhibitor-Induced Hepatitis: A Case Report of Challenging Management - Cureus
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MicroRNA-142-3p promotes renal cell carcinoma progression by targeting RhoBTB3 to regulate HIF-1 signaling and GGT/GSH pathways - Nature
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Association between Elevated Liver Enzymes and Microvascular Complications in Patients with Type 2 Diabetes: The PERSIAN Guilan Cohort Study - Via Medica Journals
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A novel method for rapid detection of a Helicobacter pylori infection using a γ-glutamyltranspeptidase-activatable fluorescent probe - Nature
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Genome-wide association and Mendelian randomization study of blood copper levels and 213 deep phenotypes in humans - Nature
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Elevated serum transaminase activities were associated with increased serum levels of iron regulatory hormone hepcidin and hyperferritinemia risk - Nature
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Predictors for incomplete response to ursodeoxycholic acid in primary biliary cholangitis. Data from a national registry of liver disease - Wiley Online Library
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Lupus Hepatitis: A Rare Manifestation Revealing Systemic Lupus Erythematosus - Cureus
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Circulating Epstein-Barr virus DNA associated with hepatic impairment and its diagnostic and prognostic role in patients with gastric cancer - Frontiers
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Effects of Ginkgo biloba Intake on Markers of Liver Function in a Large Representative Sample of the U.S. Population - Wiley
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Assessment of the relationship between serum uric acid levels and liver enzymes activity in Bangladeshi adults - Nature
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Gamma-glutamyltransferase: an effect modifier in the association between age and hypertension in a 4-year follow-up study - Nature
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γ‐Glutamyltransferase and cancer risk: The Korean cancer prevention study - Wiley Online Library
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Low serum 25-hydroxyvitamin D levels are associated with liver injury markers in the US adult population - Cambridge University Press & Assessment
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The Beneficial Effects of Oral Cotrimoxazole upon Likely Biomarkers of Oxidative Stress in Advanced Fibrotic Lung Disease - SCIRP Open Access
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The effect of anthocyanins supplementation on liver enzymes: A systematic review and meta-analysis of randomized clinical trials - Wiley Online Library
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Antioxidants For GGT Syndrome In Training Racehorses - Paulick Report
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Oncology Letters - Spandidos Publications
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Prepregnancy GGT levels predict risk of gestational diabetes mellitus - Nature
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The diagnostic approach to asymptomatic dogs with elevated liver enzyme activities - DVM360
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Liver Enzymes in Children and Adolescents - Endocrine Society
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Helicobacter pylori γ-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance - PNAS
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High GGT levels seen as scleroderma risk factor in Korean study - Scleroderma News
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Rapid imaging of thymoma and thymic carcinoma with a fluorogenic probe targeting γ-glutamyltranspeptidase - Nature
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Association between pregravid liver enzyme levels and gestational diabetes in twin pregnancies: a secondary analysis of national cohort study - Nature
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SCYL1 variants cause a syndrome with low γ-glutamyl-transferase cholestasis, acute liver failure, and neurodegeneration (CALFAN) - Nature
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Glutathione S -conjugates as prodrugs to target drug-resistant tumors - Frontiers
Why This Topic Is Trending
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