Why is "Germinal center" trending?

Search Interest Perspective

• BLIMP1 tunes germinal center B cell responses to limit clonal dominance - Nature
• PRELID1 and VDAC3 Coordinate a Senescence-Like State in Germinal Center B Cells to Promote IL-7–Driven Antitumor Immunity in Colorectal Cancer - Wiley
• BLIMP1 shapes germinal center B cell clonal diversity by gating chromatin accessibility during light-to-dark zone transition - Nature
• Epigenetic plasticity in germinal center B cells may help explain lymphoma origins - News-Medical
• Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses - Medical Xpress
• BCL6 inhibition: a promising approach to prevent germinal center-driven allo-immune responses - Frontiers
• Vaccines combining slow release and follicle targeting of antigens increase germinal center B cell diversity and clonal expansion - Science | AAAS
• Lymphocyte-derived cholinergic circuits modulate germinal center output and B cell activation - Nature
• Germinal center–dependent and –independent memory B cells produced throughout the immune response - Rockefeller University Press
• Immunology & Cell Biology | ASI Journal - Wiley Online Library
• Cold-blooded vertebrates evolved organized germinal center–like structures - Science | AAAS
• Foot-and-mouth disease virus-derived dendrimer peptides induce germinal center-dependent antibody responses and IgG1 plasma cell differentiation in mice - Nature
• Extrafollicular B Cell Responses—Is One Tent Big Enough? - Baumgarth - 2025 - Immunological Reviews - Wiley Online Library
• CFP1 promotes germinal center affinity maturation and restrains memory B cell differentiation through H3K4me3 modulation - Nature
• Prefusion-stabilized Hantaan virus glycoprotein nucleic acid vaccine elicits potent neutralizing antibody responses via germinal center activation - Nature
• The transcription complex p52–ETS1 is essential for germinal center formation - Nature
• A unique p52 NF-κB–ETS1 interaction ushers in a new paradigm of germinal center responses - Nature
• Novel specialized cell state and spatial compartments within the germinal center - Nature
• Metabolic determinants of germinal center B cell formation and responses - Nature
• Asymmetric B Cell Division in the Germinal Center Reaction - Science | AAAS
• Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift - Nature
• Immunology & Cell Biology | ASI Journal - Wiley Online Library
• Sustained antigen delivery improves germinal center reaction and increases antibody responses in neonatal mice - Nature
• Germinal Center–Derived Antibodies Promote Atherosclerosis Plaque Size and Stability - American Heart Association Journals
• Control of germinal center B cell survival and IgE production by an adaptor molecule containing PH and SH2 domains, Aps/Sh2b2 - Nature
• Germinal center-dependent and -independent immune responses of tumor-infiltrating B cells in human cancers - Nature
• Germinal center output is sustained by HELLS-dependent DNA-methylation-maintenance in B cells - Nature
• Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells - Rockefeller University Press
• Asparagine availability controls germinal center B cell homeostasis - Science | AAAS
• A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates - Nature
• Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis - Nature
• Recreation of an antigen-driven germinal center in vitro by providing B cells with phagocytic antigen - Nature
• Defects in Germinal Center Selection in SLE - Frontiers
• Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome - Rockefeller University Press
• Germinal center derived B cell memory without T cells - Rockefeller University Press
• Maf expression in B cells restricts reactive plasmablast and germinal center B cell expansion - Nature
• Dietary glutamine supports mucosal germinal center B cell lymphomas - Nature
• The lipid globotriaosylceramide promotes germinal center B cell responses and antiviral immunity - Science | AAAS
• Maturation of germinal center B cells after influenza virus vaccination in humans - Rockefeller University Press
• Defective germinal center selection results in persistence of self-reactive B cells from the primary to the secondary repertoire in Primary Antiphospholipid Syndrome - Nature
• Complement-in’ the germinal center response - Nature
• Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization - Nature
• Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density - Nature
• PRMT5 is essential for B cell development and germinal center dynamics - Nature
• Spatiotemporal resolution of germinal center Tfh cell differentiation and divergence from central memory CD4 - Nature
• Dynamic regulation of B cell complement signaling is integral to germinal center responses - Nature
• Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma - Haematologica
• SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques - Nature
• Investigating the Mechanism of Germinal Center Shutdown - Frontiers
• Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b - Nature
• Tingible body macrophages: Gargantuan chameleons of the germinal center - Rockefeller University Press
• Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis - Nature
• Distinct metabolic requirements regulate B cell activation and germinal center responses - Nature
• Subgrouping germinal center-derived B-cell lymphomas based on machine learning-deduced DNA methylation modules | Leukemia - Nature
• TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions - Nature
• The germinal center in the pathogenesis of B cell lymphomas - Pasqualucci - 2023 - Hematological Oncology - Wiley Online Library
• The microanatomic segregation of selection by apoptosis in the germinal center - Science | AAAS
• Genetic manipulation and immortalized culture of ex vivo primary human germinal center B cells - Nature
• Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma - Rockefeller University Press
• B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice - Rockefeller University Press
• Germinal center TFH cells: T(w)o be or not t(w)o be, IL-6 is the answer - Science | AAAS
• Directing traffic in the germinal center roundabout - Nature
• Compartments and Connections Within the Germinal Center - Frontiers
• A new perspective is needed for positive selection of germinal center B cells with higher-affinity B cell receptors - Nature
• BCL-6 Protein Is Expressed in Germinal-Center B Cells - ScienceDirect.com
• Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment - Nature
• STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells - Rockefeller University Press
• Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules - Nature
• Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses - Nature
• UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease - Nature
• Ephrin B1–mediated repulsion and signaling control germinal center T cell territoriality and function - Science | AAAS
• A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells - Nature
• SUMO-specific protease 1 regulates germinal center B cell response through deSUMOylation of PAX5 - PNAS
• 13 cells are stabilized by JunB to mediate allergen germinal center responses - Nature
• Human germinal center transcriptional programs are de-synchronized in B cell lymphoma - Nature
• Germinal-center development of memory B cells driven by IL-9 from follicular helper T cells - Nature
• AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis - Nature
• Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus - ASM Journals
• Role of affinity in plasma cell development in the germinal center light zone - Rockefeller University Press
• Regulated selection of germinal-center cells into the memory B cell compartment - Nature
• Arid1a-dependent canonical BAF complex suppresses inflammatory programs to drive efficient germinal center B cell responses - Nature
• cells progressively differentiate to regulate the germinal center response - Nature
• Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing - Rockefeller University Press
• Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory - Science | AAAS
• Germinal center B cells recognize antigen through a specialized immune synapse architecture - Nature
• Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis - Nature
• Belatacept inhibit human B cell germinal center development in immunodeficient mice - Nature
• New perspectives on the regulation of germinal center reaction via αvβ8- mediated activation of TGFβ - Frontiers
• cells to fortify the germinal center - Nature
• Integrated single-cell transcriptomics and epigenomics reveals strong germinal center–associated etiology of autoimmune risk loci - Science | AAAS
• When the body's B cell training grounds stay open after hours - The Rockefeller University
• The RNA-binding protein hnRNP F is required for the germinal center B cell response - Nature
• Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses - Rockefeller University Press
• Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation - PNAS
• Subcapsular sinus macrophages maximize germinal center development in non-draining lymph nodes during blood-borne viral infection - Science | AAAS
• Germinal Center Activity Shows Potential As Target of Rituximab in NMOSD - Neurology Live
• Activation and maturation of antigen-specific B cells in nonectopic lung infiltrates are independent of germinal center reactions in the draining lymph node - Nature
• Gastrointestinal germinal center B cell depletion and reduction in IgA+ plasma cells in HIV-1 infection - Science | AAAS
• Brg1 Supports B Cell Proliferation and Germinal Center Formation Through Enhancer Activation - Frontiers
• FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human - Nature