Why is "Granulocyte-macrophage colony-stimulating factor" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-05-09 04:51:08
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Granulocyte-macrophage_colony-stimulating_factor entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-05-09 and was most recently seen on 2026-05-09.
Wikipedia Overview
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim.
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Trending Topic Today
Search Interest Perspective
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Proinflammatory monocyte-derived granulocyte-macrophage colony-stimulating factor fuels airway inflammation in bronchopulmonary dysplasia - Nature
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Immune-modulating therapy with granulocyte-macrophage colony-stimulating factor (GM-CSF) in refractory rhino-orbital-cerebral mucormycosis – a case report - Frontiers
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mGem: When immunity turns against itself—GM-CSF autoantibodies drive opportunistic infection risk - ASM Journals
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Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities - The Lancet
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Granulocyte-Macrophage Colony Stimulating Factor As an Indirect Mediator of Nociceptor Activation and Pain - Journal of Neuroscience
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Synthesis of granulocyte–macrophage colony-stimulating factor as homogeneous glycoforms and early comparisons with yeast cell-derived material - PNAS
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Recombinant Granulocyte-Macrophage Colony-Stimulating Factor after Autologous Bone Marrow Transplantation for Lymphoid Cancer - The New England Journal of Medicine
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Production of interleukin-6 and granulocyte-macrophage colony-stimulating factor by murine iris and ciliary body explants. | IOVS | ARVO Journals - ARVO Journals
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Granulocyte-macrophage colony-stimulating factor: an immunotarget for sepsis and COVID-19 - Nature
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Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities - The Lancet
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Human Granulocyte Macrophage Colony-Stimulating Factor Enhances Antibiotic Susceptibility of Pseudomonas aeruginosa Persister Cells - Nature
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Granulocyte-macrophage colony stimulating factor (GM-CSF) is fully expressed in the genital tract, seminal plasma and spermatozoa of male pigs - Nature
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Sintilimab in combination with stereotactic body radiotherapy and granulocyte-macrophage colony-stimulating factor in metastatic non-small cell lung cancer: The multicenter SWORD phase 2 trial - Nature
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Association of granulocyte macrophage colony-stimulating factor and interleukin-17 levels with obsessive–compulsive disorder: a case–control study findings - Nature
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Tumour-derived CSF2/granulocyte macrophage colony stimulating factor controls myeloid cell accumulation and progression of gliomas - Nature
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Granulocyte macrophage colony-stimulating factor is required for aortic dissection/intramural haematoma - Nature
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The role of granulocyte macrophage-colony-stimulating factor in acute intestinal inflammation - Nature
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Accelerating infectious wound healing through bacterial cellulose/ag composite film enriched with GM-CSF - Nature
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Intraperitoneal administration of fosfomycin, metronidazole, and granulocyte-macrophage colony-stimulating factor in patients undergoing appendectomy is safe: a phase II clinical trial - Nature
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The laminin receptor modulates granulocyte–macrophage colony-stimulating factor receptor complex formation and modulates its signaling - PNAS
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An epithelial-to-mesenchymal transition-inducing potential of granulocyte macrophage colony-stimulating factor in colon cancer - Nature
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An oncolytic adenovirus expressing granulocyte macrophage colony-stimulating factor shows improved specificity and efficacy for treating human solid tumors - Nature
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Effects of Recombinant Human Granulocyte–Macrophage Colony-Stimulating Factor in Patients with Myelodysplastic Syndromes - The New England Journal of Medicine
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Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma - PNAS
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The Distribution of Granulocyte-Macrophage Colony-Stimulating Factor and Its Receptor in the Developing Human Fetus - Nature
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Effect of Priming with Granulocyte Colony-Stimulating Factor on the Outcome of Chemotherapy for Acute Myeloid Leukemia - The New England Journal of Medicine
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Effect of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor on Chemotherapy-Induced Myelosuppression - The New England Journal of Medicine
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Inhaled GM-CSF for Pulmonary Alveolar Proteinosis - The New England Journal of Medicine
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Granulocyte–Macrophage Colony-Stimulating Factor after Initial Chemotherapy for Elderly Patients with Primary Acute Myelogenous Leukemia - The New England Journal of Medicine
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Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor - The New England Journal of Medicine
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Rhinovirus 16 3C Protease Induces Interleukin-8 and Granulocyte-Macrophage Colony-Stimulating Factor Expression in Human Bronchial Epithelial Cells - Nature
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Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor - The New England Journal of Medicine
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Tumor-specific oncolytic adenoviruses expressing granulocyte macrophage colony-stimulating factor or anti-CTLA4 antibody for the treatment of cancers - Nature
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GM-CSF: A Double-Edged Sword in Cancer Immunotherapy - Frontiers
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Effect of priming with granulocyte–macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group - Nature
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Cryptococcus deuterogattii VGIIa Infection Associated with Travel to the Pacific Northwest Outbreak Region in an Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibody-Positive Patient in the United States - ASM Journals
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A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy - Nature
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The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils - Nature
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Effect of Recombinant Human Granulocyte–Macrophage Colony-Stimulating Factor on Myelopoiesis in the Acquired Immunodeficiency Syndrome - The New England Journal of Medicine
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Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis - The New England Journal of Medicine
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Is There a Role for Hematopoietic Growth Factors During Sepsis? - Frontiers
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GM-CSF Autoantibodies and Neutrophil Dysfunction in Pulmonary Alveolar Proteinosis - The New England Journal of Medicine
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Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update - Frontiers
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Granulocyte macrophage-colony stimulating factor and interleukin-3 increase expression of type II tumour necrosis factor receptor, increasing susceptibility to tumour necrosis factor-induced apoptosis. Control of leukaemia cell life/death switching - Nature
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CD4+ T cells require Ikaros to inhibit their differentiation toward a pathogenic cell fate - PNAS
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Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes - Nature
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GM-CSF-based treatments in COVID-19: reconciling opposing therapeutic approaches - Nature
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Stimulatory versus suppressive effects of GM-CSF on tumor progression in multiple cancer types - Nature
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The anti-GD2 monoclonal antibody naxitamab plus GM-CSF for relapsed or refractory high-risk neuroblastoma: a phase 2 clinical trial - Nature
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Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma - The New England Journal of Medicine
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Effects of formoterol and budesonide on GM-CSF and IL-8 secretion by triggered human bronchial epithelial cells - ERS - European Respiratory Society
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Erythropoietin Plus Granulocyte Macrophage Factor for Myelodysplastic Syndrome - news.cancerconnect.com
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Inhaled recombinant GM-CSF reduces the need for whole lung lavage and improves gas exchange in autoimmune pulmonary alveolar proteinosis patients - ERS - European Respiratory Society
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Statins Effective in Treating Pulmonary Alveolar Proteinosis - Research Horizons
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Sargramostim for Active Crohn's Disease - The New England Journal of Medicine
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Growth Factors as Immunotherapeutic Targets in Cardiovascular Disease - American Heart Association Journals
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Differential regulation of microglial states by colony stimulating factors - Frontiers
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GM-CSF Monocyte-Derived Cells and Langerhans Cells As Part of the Dendritic Cell Family - Frontiers
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Granulocyte Colony-Stimulating Factor in Severe Chemotherapy-Induced Afebrile Neutropenia - The New England Journal of Medicine
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Changes of CD14 and CD1a Expression in Response to IL-4 and Granulocyte-Macrophage Colony-Stimulating Factor Are Different in Cord Blood and Adult Blood Monocytes - Nature
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MASH-COVID Trial Hints at Role for Targeting GM-CSF in Hyperinflammatory COVID-19 - Cleveland Clinic
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Natural Drug Approved for White Blood Cell Recovery Can Be Repurposed To Improve Cognition in Alzheimer’s Patients - Genetic Engineering and Biotechnology News
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Induction of apoptosis in human hematopoietic U937 cells by granulocyte–macrophage colony-stimulating factor: possible existence of caspase 3-like pathway - Nature
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Granulocyte-macrophage colony stimulating factor administered as prophylaxis for reduction of sepsis in extremely preterm, small for gestational age neonates (the PROGRAMS trial): a single-blind, multicentre, randomised controlled trial - The Lancet
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GM-CSF, G-CSF or no cytokine therapy with anti-GD2 immunotherapy for high-risk neuroblastoma - Wiley Online Library
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Stimulating severe COVID-19: the potential role of GM-CSF antagonism - The Lancet
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GM-CSF-Dependent Inflammatory Pathways - Frontiers
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Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis - Science | AAAS
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Functional Analysis of Anti-cytokine Autoantibodies Using Flow Cytometry - Frontiers
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TH Cells and Cytokines in Encephalitogenic Disorders - Frontiers
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Which AML subsets benefit from leukemic cell priming during chemotherapy? Long-term analysis of the ALFA-9802 GM-CSF study - Wiley
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Unilineage monocytopoiesis in hematopoietic progenitor culture: switching cytokine treatment at all Mo developmental stages induces differentiation into dendritic cells - Nature
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Bovine Derived in vitro Cultures Generate Heterogeneous Populations of Antigen Presenting Cells - Frontiers
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Sargramostim (rhu GM-CSF) and immune checkpoint inhibitors - Oncology Central
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A novel subset of helper T cells promotes immune responses by secreting GM-CSF - Nature
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Defects in Macrophage Reprogramming in Cancer Therapy: The Negative Impact of PD-L1/PD-1 - Frontiers
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Partner Therapeutics' Leukine® (sargramostim) Receives Approval in Japan to Treat Autoimmune Pulmonary Alveolar Proteinosis (aPAP) - PR Newswire
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Overview of culture surfaces tested. - PLOS
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BARDA and Partner Therapeutics continue partnership around development of LEUKINE® (sargramostim, rhu GM-CSF) to potentially improve patient care for sepsis - PR Newswire
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Modeling the Hematopoietic Landscape - Frontiers
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.